Author details

Full Name

Thomas Pertel

Affiliation

ORCID

Career Start Year

2003

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36518079	Detection of chromosomal alteration after infusion of gene-edited allogeneic CAR TÂ cells.		2023
37938768	Latent human herpesvirus 6 is reactivated in CAR T cells.	Nature	2023
34145373	Gene-edited healthy donor CAR T cells show superior anti-tumour activity compared to CAR T cells derived from patients with lymphoma in an in vivo model of high-grade lymphoma.	Leukemia	2021
31005597	Preclinical Evaluation of Allogeneic CAR T Cells Targeting BCMA for the Treatment of Multiple Myeloma.	Mol Ther	2019
29308307	Blockade of Tim-3 binding to phosphatidylserine and CEACAM1 is a shared feature of anti-Tim-3 antibodies that have functional efficacy.	OncoImmunology	2018
29895885	A Versatile Safeguard for Chimeric Antigen Receptor T-Cell Immunotherapies.	Scientific Reports	2018
26982724	Corrigendum: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.	Nature	2016
27197182	ICOS Promotes the Function of CD4+ Effector T Cells during Anti-OX40-Mediated Tumor Rejection.	Cancer Research	2016
27455421	Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1.	Nat Immunol	2016
26575988	Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa.	PLoS Med	2015
25363763	CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.	Nature	2015
25914168	A pharmacogenetic study implicates SLC9a9 in multiple sclerosis disease activity.	Ann Neurol	2015
25614966	An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction.	Nature Communications	2015
26714756	Identification of a novel mechanism of action of fingolimod (FTY720) on human effector T cell function through TCF-1 upregulation.	J Neuroinflammation	2015
26181333	Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to Integration.	PLoS Pathogens	2015
26153760	Corrigendum: An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction.	Nature Communications	2015
25526311	Dysfunctional HIV-specific CD8+ T cell proliferation is associated with increased caspase-8 activity and mediated by necroptosis.	Immunity	2014
25373910	Comprehensive identification of host modulators of HIV-1 replication using multiple orthologous RNAi reagents.	Cell Rep	2014
23658454	The CD225 domain of IFITM3 is required for both IFITM protein association and inhibition of influenza A virus and dengue virus replication.	J Virol	2013
23077300	TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity.	Journal of Virology	2013
23041316	Reactivation of latent HIV-1 by inhibition of BRD4.	Cell Rep	2012
22378925	HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome.	Sci Transl Med	2012
22446628	IFITM3 restricts the morbidity and mortality associated with influenza.	Nature	2012
21696578	Vpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon.	Retrovirology	2011
21345949	TRIM22 inhibits HIV-1 transcription independently of its E3 ubiquitin ligase activity, Tat, and NF-kappaB-responsive long terminal repeat elements.	Journal of Virology	2011
21512573	TRIM5 is an innate immune sensor for the retrovirus capsid lattice.	Nature	2011
22046135	IFITM3 inhibits influenza A virus infection by preventing cytosolic entry.	PLoS Pathog	2011
20419163	Polarization of migrating monocytic cells is independent of PI 3-kinase activity.	PLoS ONE	2010
21085665	Cyclophilin B interacts with sodium-potassium ATPase and is required for pump activity in proximal tubule cells of the kidney.	PLoS ONE	2010
20927389	Cyclosporine A-sensitive, cyclophilin B-dependent endoplasmic reticulum-associated degradation.	PLoS ONE	2010
20357094	p62/sequestosome-1 associates with and sustains the expression of retroviral restriction factor TRIM5alpha.	Journal of Virology	2010
19805154	Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1.	Proc Natl Acad Sci U S A	2009
19741300	Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components.	Journal of Clinical Investigation	2009
19153241	An invariant surface patch on the TRIM5alpha PRYSPRY domain is required for retroviral restriction but dispensable for capsid binding.	Journal of Virology	2009
18417469	A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal.	Journal of Biological Chemistry	2008
18829761	Characterization of simian immunodeficiency virus SIVSM/human immunodeficiency virus type 2 Vpx function in human myeloid cells.	Journal of Virology	2008
17522232	Vif counteracts a cyclophilin A-imposed inhibition of simian immunodeficiency viruses in human cells.	Journal of Virology	2007
16227319	Expression and muscarinic receptor coupling of Lyn kinase in cultured human airway smooth muscle cells.	American Journal of Physiology - Lung Cellular and Molecular Physiology	2006
15821021	Isoproterenol induces actin depolymerization in human airway smooth muscle cells via activation of an Src kinase and GS.	American Journal of Physiology - Lung Cellular and Molecular Physiology	2005
14758092	Growth inhibitory activity of extracts and purified components of black cohosh on human breast cancer cells.	Breast Cancer Research and Treatment	2004
12530974	Impairment of NK cell function by NKG2D modulation in NOD mice.	Immunity	2003