Author details

Full Name

Todd M Allen

Affiliation

ORCID

Career Start Year

1996

Papers

196

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37461565	Validation of Dried Blood Spots for Capturing Hepatitis C Virus Diversity for Genomic Surveillance.		2023
34935145	Poly I:C and STING agonist-primed DC increase lymphoid tissue polyfunctional HIV-1-specific CD8 T cells and limit CD4 T-cell loss in BLT mice.	European Journal of Immunology	2022
34448809	Identification of Genetically Related HCV Infections Among Self-Described Injecting Partnerships.	Clinical Infectious Diseases	2022
34496223	Functional impairment of HIV-specific CD8<sup>+</sup> TÂ cells precedes aborted spontaneous control of viremia.	Immunity	2021
34122425	Innate Immune Reconstitution in Humanized Bone Marrow-Liver-Thymus (HuBLT) Mice Governs Adaptive Cellular Immune Function and Responses to HIV-1 Infection.	Front Immunol	2021
34312547	Epigenetic scars of CD8<sup>+</sup> T cell exhaustion persist after cure of chronic infection in humans.	Nat Immunol	2021
34312544	Differentiation of exhausted CD8<sup>+</sup> T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory.	Nat Immunol	2021
33496239	Hepatitis C Virus Transmission Clusters in Public Health and Correctional Settings, Wisconsin, USA, 2016-2017.	Emerging Infectious Diseases	2021
33326789	HIV Antibody Fc N-Linked Glycosylation Is Associated with Viral Rebound.	Cell Rep	2020
32392227	Gp41-targeted antibodies restore infectivity of a fusion-deficient HIV-1 envelope glycoprotein.	PLoS Pathog	2020
32868878	Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo.	Nature Medicine	2020
31375576	Immunization of BLT Humanized Mice Redirects T Cell Responses to Gag and Reduces Acute HIV-1 Viremia.	Journal of Virology	2019
30381486	Metagenomic Sequencing of HIV-1 in the Blood and Female Genital Tract Reveals Little Quasispecies Diversity during Acute Infection.	J Virol	2019
30629922	HIV-1 Balances the Fitness Costs and Benefits of Disrupting the Host Cell Actin Cytoskeleton Early after Mucosal Transmission.		2019
31041340	Role of HCV Viremia in Corroborated HCV Transmission Events Within Young Adult Injecting Partnerships.	Open Forum Infectious Diseases	2019
31027215	Lower Broadly Neutralizing Antibody Responses in Female Versus Male HIV-1 Infected Injecting Drug Users.	Viruses	2019
31160798	Humanized immune system mouse models: progress, challenges and opportunities.	Nat Immunol	2019
30718881	Capturing sequence diversity in metagenomes with comprehensive and scalable probe design.	Nat Biotechnol	2019
31048489	Structural topology defines protective CD8<sup>+</sup> T cell epitopes in the HIV proteome.	Science	2019
29338738	Rapid HIV disease progression following superinfection in an HLA-B27:05/B57:01-positive transmission recipient.	Retrovirology	2018
29875239	<i>Mamu-B*17</i><sup>+</sup> Rhesus Macaques Vaccinated with <i>env</i>, <i>vif</i>, and <i>nef</i> Manifest Early Control of SIVmac239 Replication.	J Virol	2018
27936416	Antigen recognition-triggered drug delivery mediated by nanocapsule-functionalized cytotoxic T-cells.	Biomaterials	2017
28768869	Protective Efficacy of Broadly Neutralizing Antibodies with Incomplete Neutralization Activity against Simian-Human Immunodeficiency Virus in Rhesus Monkeys.	Journal of Virology	2017
28503929	Rare Control of SIVmac239 Infection in a Vaccinated Rhesus Macaque.	AIDS Res Hum Retroviruses	2017
28750738	Dengue Virus Evades AAV-Mediated Neutralizing Antibody Prophylaxis in Rhesus Monkeys.	Molecular Therapy	2017
29045899	Early Transcriptional Divergence Marks Virus-Specific Primary Human CD8<sup>+</sup> T Cells in Chronic versus Acute Infection.	Immunity	2017
28285909	Interferon-I: The PiÃ¨ce de RÃ©sistance of HIV-1 Transmission?	Trends in Microbiology	2017
27531641	High resolution sequencing of hepatitis C virus reveals limited intra-hepatic compartmentalization in end-stage liver disease.	Journal of Hepatology	2017
28253319	Early type I Interferon response induces upregulation of human Î²-defensin 1 during acute HIV-1 infection.	PLoS One	2017
27819061	Use of Dried Blood Spots to Elucidate Full-Length Transmitted/Founder HIV-1 Genomes.	Pathogens and Immunity	2016
27183217	Impact of pre-adapted HIV transmission.	Nat Med	2016
27045383	Deep sequencing of hepatitis C virus reveals genetic compartmentalization in cerebrospinal fluid from cognitively impaired patients.	Liver International	2016
27357340	Protection of Humanized Mice From Repeated Intravaginal HIV Challenge by Passive Immunization: A Model for Studying the Efficacy of Neutralizing Antibodies In Vivo.	Journal of Infectious Diseases	2016
27163788	Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus.	PLoS Pathog	2016
27158667	Innate immune reconstitution with suppression of HIV-1.	JCI Insight	2016
26437376	Effect of scavenger receptor class B type I antagonist ITX5061 in patients with hepatitis C virus infection undergoing liver transplantation.	Liver Transplantation	2016
26643479	Naturally Occurring Subclinical Endotoxemia in Humans Alters Adaptive and Innate Immune Functions through Reduced MAPK and Increased STAT1 Phosphorylation.	Journal of Immunology	2016
26446603	Distinct Escape Pathway by Hepatitis C Virus Genotype 1a from a Dominant CD8+ T Cell Response by Selection of Altered Epitope Processing.	Journal of Virology	2016
27760342	Antiviral CD8<sup>+</sup> T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion.	Immunity	2016
27789799	The epigenetic landscape of T cell exhaustion.	Science	2016
26292326	Vaccine-Induced Simian Immunodeficiency Virus-Specific CD8+ T-Cell Responses Focused on a Single Nef Epitope Select for Escape Variants Shortly after Infection.	J Virol	2015
25883387	Hepatitis C Virus Reinfection and Spontaneous Clearance of Reinfection--the InC3 Study.	Journal of Infectious Diseases	2015
26123575	Disease progression despite protective HLA expression in an HIV-infected transmission pair.	Retrovirology	2015
26083316	BLT humanized mice as a small animal model of HIV infection.	Current Opinion in Virology	2015
25043727	Increased frequency and function of KIR2DL1-3âº NK cells in primary HIV-1 infection are determined by HLA-C group haplotypes.	European Journal of Immunology	2014
25517468	Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9.	Cell Stem Cell	2014
23978718	HLA-B*27 subtype specificity determines targeting and viral evolution of a hepatitis C virus-specific CD8+ T cell epitope.	J Hepatol	2014
25212686	Early immune adaptation in HIV-1 revealed by population-level approaches.	Retrovirology	2014
24521131	How a single patient influenced HIV research--15-year follow-up.	New England Journal of Medicine	2014
25013080	HIV transmission. Selection bias at the heterosexual HIV-1 transmission bottleneck.	Science	2014