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| 37637936 | Multicellular Complex Tumor Spheroid Response to DNA Repair Inhibitors in Combination with DNA-damaging Drugs. | Cancer Res Commun | 2023 |
| 37550087 | Targeted Investigational Oncology Agents in the NCI-60: A Phenotypic Systems-based Resource. | Mol Cancer Ther | 2023 |
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| 35209819 | Antibody-drug Conjugate Targets, Drugs, and Linkers. | Curr Cancer Drug Targets | 2022 |
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| 33063584 | The development of β-selective glycosylation reactions with benzyl substituted 2-deoxy-1,4-dithio-D-<i>erythro</i>-pentofuranosides: enabling practical multi-gram syntheses of 4'-Thio-2'-deoxycytidine (T-dCyd) and 5-aza-4'-thio-2'-deoxycytidine (aza-T-dCyd) to support clinical development. | Nucleosides Nucleotides Nucleic Acids | 2021 |
| 33811149 | F-aza-T-dCyd (NSC801845), a Novel Cytidine Analog, in Comparative Cell Culture and Xenograft Studies with the Clinical Candidates T-dCyd, F-T-dCyd, and Aza-T-dCyd. | Mol Cancer Ther | 2021 |
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| 33811149 | F-aza-T-dCyd (NSC801845), a Novel Cytidine Analog, in Comparative Cell Culture and Xenograft Studies with the Clinical Candidates T-dCyd, F-T-dCyd, and Aza-T-dCyd. | Mol Cancer Ther | 2021 |
| 28766886 | Small cell lung carcinoma cell line screen of etoposide/carboplatin plus a third agent. | Cancer Med | 2017 |
| 28766886 | Small cell lung carcinoma cell line screen of etoposide/carboplatin plus a third agent. | Cancer Med | 2017 |
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| 27247353 | Small Cell Lung Cancer Screen of Oncology Drugs, Investigational Agents, and Gene and microRNA Expression. | J Natl Cancer Inst | 2016 |
| 26501955 | Comprehensive characterization of the Published Kinase Inhibitor Set. | Nat Biotechnol | 2016 |
| 26683772 | Bromodomain and hedgehog pathway targets in small cell lung cancer. | Cancer Lett | 2016 |
| 26501955 | Comprehensive characterization of the Published Kinase Inhibitor Set. | Nat Biotechnol | 2016 |
| 27247353 | Small Cell Lung Cancer Screen of Oncology Drugs, Investigational Agents, and Gene and microRNA Expression. | J Natl Cancer Inst | 2016 |
| 26351324 | Sarcoma Cell Line Screen of Oncology Drugs and Investigational Agents Identifies Patterns Associated with Gene and microRNA Expression. | Mol Cancer Ther | 2015 |
| 26351324 | Sarcoma Cell Line Screen of Oncology Drugs and Investigational Agents Identifies Patterns Associated with Gene and microRNA Expression. | Mol Cancer Ther | 2015 |
| 24356813 | Stereospecific PARP trapping by BMN 673 and comparison with olaparib and rucaparib. | Mol Cancer Ther | 2014 |
| 25448049 | Characterization of acute biliary hyperplasia in Fisher 344 rats administered the indole-3-carbinol analog, NSC-743380. | Toxicol Appl Pharmacol | 2014 |
| 25269479 | ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase i inhibitors by disabling DNA replication initiation and fork elongation responses. | Cancer Res | 2014 |
| 24356813 | Stereospecific PARP trapping by BMN 673 and comparison with olaparib and rucaparib. | Mol Cancer Ther | 2014 |
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| 24650937 | Rationale for poly(ADP-ribose) polymerase (PARP) inhibitors in combination therapy with camptothecins or temozolomide based on PARP trapping versus catalytic inhibition. | J Pharmacol Exp Ther | 2014 |
| 25448049 | Characterization of acute biliary hyperplasia in Fisher 344 rats administered the indole-3-carbinol analog, NSC-743380. | Toxicol Appl Pharmacol | 2014 |
| 25269479 | ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase i inhibitors by disabling DNA replication initiation and fork elongation responses. | Cancer Res | 2014 |
| 25032700 | NCI-60 whole exome sequencing and pharmacological CellMiner analyses. | PLoS One | 2014 |
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| 23566514 | Discovery and synthesis of novel 4-aminopyrrolopyrimidine Tie-2 kinase inhibitors for the treatment of solid tumors. | Bioorg Med Chem Lett | 2013 |
| 23566514 | Discovery and synthesis of novel 4-aminopyrrolopyrimidine Tie-2 kinase inhibitors for the treatment of solid tumors. | Bioorg Med Chem Lett | 2013 |
| 22802077 | CellMiner: a web-based suite of genomic and pharmacologic tools to explore transcript and drug patterns in the NCI-60 cell line set. | Cancer Res | 2012 |
| 22802077 | CellMiner: a web-based suite of genomic and pharmacologic tools to explore transcript and drug patterns in the NCI-60 cell line set. | Cancer Res | 2012 |
| 20507089 | Discovery tactics to mitigate toxicity risks due to reactive metabolite formation with 2-(2-hydroxyaryl)-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4(3h)-one derivatives, potent calcium-sensing receptor antagonists and clinical candidate(s) for the treatment of osteoporosis. | Chem Res Toxicol | 2010 |
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| 20507089 | Discovery tactics to mitigate toxicity risks due to reactive metabolite formation with 2-(2-hydroxyaryl)-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4(3h)-one derivatives, potent calcium-sensing receptor antagonists and clinical candidate(s) for the treatment of osteoporosis. | Chem Res Toxicol | 2010 |
| 20481595 | Design of selective, ATP-competitive inhibitors of Akt. | J Med Chem | 2010 |
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| 19625189 | Short-acting 5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4(3H)-one derivatives as orally-active calcium-sensing receptor antagonists. | Bioorg Med Chem Lett | 2009 |
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| 18456494 | Synthesis and structure based optimization of novel Akt inhibitors. | Bioorg Med Chem Lett | 2008 |
| 17942920 | Discovery and pharmacologic characterization of CP-724,714, a selective ErbB2 tyrosine kinase inhibitor. | Cancer Res | 2007 |
| 17942920 | Discovery and pharmacologic characterization of CP-724,714, a selective ErbB2 tyrosine kinase inhibitor. | Cancer Res | 2007 |
| 16632359 | Discovery of novel isothiazole inhibitors of the TrkA kinase: structure-activity relationship, computer modeling, optimization, and identification of highly potent antagonists. | Bioorg Med Chem Lett | 2006 |
| 16632359 | Discovery of novel isothiazole inhibitors of the TrkA kinase: structure-activity relationship, computer modeling, optimization, and identification of highly potent antagonists. | Bioorg Med Chem Lett | 2006 |
| 12519066 | Identification of phenylisoxazolines as novel and viable antibacterial agents active against Gram-positive pathogens. | J Med Chem | 2003 |
| 12519066 | Identification of phenylisoxazolines as novel and viable antibacterial agents active against Gram-positive pathogens. | J Med Chem | 2003 |
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| 12859950 | Achieving selectivity between highly homologous tyrosine kinases: a novel selective erbB2 inhibitor. | Biochem Biophys Res Commun | 2003 |