Author details

Full Name

Nishant K Singh

Affiliation

ORCID

Career Start Year

2011

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
34260940	HLA class-I-peptide stability mediates CD8<sup>+</sup> TÂ cell immunodominance hierarchies and facilitates HLA-associated immune control of HIV.	Cell Rep	2021
34072710	Effect of Different Lubricating Environment on the Tribological Performance of CNT Filled Glass Reinforced Polymer Composite.	Materials	2021
33468649	Structurally silent peptide anchor modifications allosterically modulate T cell recognition in a receptor-dependent manner.	Proceedings of the National Academy of Sciences of the United States of America	2021
34265281	Structure-guided TÂ cell vaccine design for SARS-CoV-2 variants and sarbecoviruses.	Cell	2021
33074657	An Engineered T Cell Receptor Variant Realizes the Limits of Functional Binding Modes.	Biochemistry	2020
31589793	Geometrical characterization of T cell receptor binding modes reveals class-specific binding to maximize access to antigen.	Proteins	2020
32877699	Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19.	Cell	2020
30617019	Improving T Cell Receptor On-Target Specificity via Structure-Guided Design.	Molecular Therapy	2019
29264697	Correction to: Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells.	Cancer Immunol Immunother	2018
29052782	Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells.	Cancer Immunol Immunother	2018
28923982	Emerging Concepts in TCR Specificity: Rationalizing and (Maybe) Predicting Outcomes.	J Immunol	2017
28572406	How an alloreactive T-cell receptor achieves peptide and MHC specificity.	Proceedings of the National Academy of Sciences of the United States of America	2017
27624308	A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces.	Protein Eng Des Sel	2016
26884163	How structural adaptability exists alongside HLA-A2 bias in the human Î±Î² TCR repertoire.	Proc Natl Acad Sci U S A	2016
27238970	An Engineered Switch in T Cell Receptor Specificity Leads to an Unusual but Functional Binding Geometry.	Structure	2016
27094300	Computational Modeling of T Cell Receptor Complexes.	Methods Mol Biol	2016
27094299	Computational Reprogramming of T Cell Antigen Receptor Binding Properties.	Methods Mol Biol	2016
27705812	Ligand-Driven T Cell Receptor Selection in Celiac Disease.	Structure	2016
27681597	Deep Mutational Scans as a Guide to Engineering High Affinity T Cell Receptor Interactions with Peptide-bound Major Histocompatibility Complex.	Journal of Biological Chemistry	2016
24550723	Computational design of the affinity and specificity of a therapeutic T cell receptor.	PLoS Comput Biol	2014
25376839	Changing the peptide specificity of a human T-cell receptor by directed evolution.	Nat Commun	2014
23856028	Recombinant leukemia inhibitory factor suppresses human medullary thyroid carcinoma cell line xenografts in mice.	Cancer Letters	2013
21728649	Transport coefficients for the shear dynamo problem at small Reynolds numbers.		2011