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Author Details

Emanuela Ricciotti
Perelman School of Medicine, University of Pennsylvania
2001
57
28
PMIDPaper TitleJournal TitlePublished Year
36574346Nonsteroidal anti-inflammatory drugs as a targeted therapy for bone marrow failure in Ghosal hematodiaphyseal dysplasia.Blood2023
37948331Deep phenotyping of the lipidomic response in COVID-19 and non-COVID-19 sepsis.Clin Transl Med2023
37388454Editorial: Eicosanoids in cancer, Volume II.Front Pharmacol2023
37398323Deep Phenotyping of the Lipidomic Response in COVID and non-COVID Sepsis.bioRxiv2023
36049621Cigarette smoke is associated with up-regulation of inducible NOS and COX-2 protein expression and activity in granulosa cells of women undergoing in vitro fertilization.Reprod Toxicol2022
34101620Sex-dependent compensatory mechanisms preserve blood pressure homeostasis in prostacyclin receptor-deficient mice.J Clin Invest2021
33893087Aspirin in Hepatocellular Carcinoma.Cancer Res2021
33502899Aspirin in the Prevention of Cardiovascular Disease and Cancer.Annu Rev Med2021
34976917Considerations for the Safe Operation of Schools During the Coronavirus Pandemic.Front Public Health2021
34566667Editorial: Eicosanoids in Cancer.Front Pharmacol2021
34303107Nonsteroidal anti-inflammatory drugs and glucocorticoids in COVID-19.Adv Biol Regul2021
32317963Pharmacological Characterization of the Microsomal Prostaglandin E<sub>2</sub> Synthase-1 Inhibitor AF3485 <i>In Vitro</i> and <i>In Vivo</i>.Front Pharmacol2020
34094421LDL-mimetic lipid nanoparticles prepared by surface KAT ligation for <i>in vivo</i> MRI of atherosclerosis.Chem Sci2020
32848762NSAID-Gut Microbiota Interactions.Front Pharmacol2020
32894506Druggable Prostanoid Pathway.Adv Exp Med Biol2020
32492880Anti-Migratory Effects of 4'-Geranyloxyferulic Acid on LPS-Stimulated U937 and HCT116 Cells via MMP-9 Down-Regulation: Involvement of ROS/ERK Signaling Pathway.Antioxidants (Basel)2020
30996346Fatty acid transport protein 2 reprograms neutrophils in cancer.Nature2019
31530843Comparative evaluation of RNA-Seq library preparation methods for strand-specificity and low input.Sci Rep2019
31553935Prostaglandin regulation of T cell biology.Pharmacol Res2019
31430883Modulation of Apoptotic Cell Death and Neuroprotective Effects of Glutathione-L-Dopa Codrug Against H<sub>2</sub>O<sub>2</sub>-Induced Cellular Toxicity.Antioxidants (Basel)2019
31248980Platelet-Specific Deletion of Cyclooxygenase-1 Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice.J Pharmacol Exp Ther2019
29765153COX-2 mediates pro-tumorigenic effects of PKCε in prostate cancer.Oncogene2018
29930022Cyclooxygenase-2, Asymmetric Dimethylarginine, and the Cardiovascular Hazard From Nonsteroidal Anti-Inflammatory Drugs.Circulation2018
30305427Lipocalin-Like Prostaglandin D Synthase but Not Hemopoietic Prostaglandin D Synthase Deletion Causes Hypertension and Accelerates Thrombogenesis in Mice.J Pharmacol Exp Ther2018
28797240A comparison of Illumina and Ion Torrent sequencing platforms in the context of differential gene expression.BMC Genomics2017
28481222Hepatic metal ion transporter ZIP8 regulates manganese homeostasis and manganese-dependent enzyme activity.J Clin Invest2017
28651847The Cardiovascular Pharmacology of Nonsteroidal Anti-Inflammatory Drugs.Trends Pharmacol Sci2017
27074574Aspirin prevents colorectal cancer metastasis in mice by splitting the crosstalk between platelets and tumor cells.Oncotarget2016
27547824A broad-spectrum lipidomics screen of antiinflammatory drug combinations in human blood.JCI Insight2016
25915600Understanding multicellular function and disease with human tissue-specific networks.Nat Genet2015
23292931COX-2, the dominant source of prostacyclin.Proc Natl Acad Sci U S A2013
23250985Myeloid cell 5-lipoxygenase activating protein modulates the response to vascular injury.Circ Res2013
22406532Niacin and biosynthesis of PGDâ¿¿by platelet COX-1 in mice and humans.J Clin Invest2012
24281340Mechanistic and pharmacological issues of aspirin as an anticancer agent.Pharmaceuticals (Basel)2012
22951221Novel aminobenzyl-acetamidine derivative modulate the differential regulation of NOSs in LPS induced inflammatory response: role of PI3K/Akt pathway.Biochim Biophys Acta2012
23075169Functionalized low-density lipoprotein nanoparticles for in vivo enhancement of atherosclerosis on magnetic resonance images.Bioconjug Chem2012
22493243Disruption of the 5-lipoxygenase pathway attenuates atherogenesis consequent to COX-2 deletion in mice.Proc Natl Acad Sci U S A2012
22553252Vascular COX-2 modulates blood pressure and thrombosis in mice.Sci Transl Med2012
22262921Effects of celecoxib on prostanoid biosynthesis and circulating angiogenesis proteins in familial adenomatous polyposis.J Pharmacol Exp Ther2012
21508345Prostaglandins and inflammation.Arterioscler Thromb Vasc Biol2011
20065114NCX 4040, a nitric oxide-donating aspirin, exerts anti-inflammatory effects through inhibition of I kappa B-alpha degradation in human monocytes.J Immunol2010
20530000Targeted deletions of cyclooxygenase-2 and atherogenesis in mice.Circulation2010
19925781Effects of AF3442 [N-(9-ethyl-9H-carbazol-3-yl)-2-(trifluoromethyl)benzamide], a novel inhibitor of human microsomal prostaglandin E synthase-1, on prostanoid biosynthesis in human monocytes in vitro.Biochem Pharmacol2010
19376970Cardiomyocyte cyclooxygenase-2 influences cardiac rhythm and function.Proc Natl Acad Sci U S A2009
19630805The translational therapeutics of prostaglandin inhibition in atherothrombosis.J Thromb Haemost2009
17993463Tetranor PGDM, an abundant urinary metabolite reflects biosynthesis of prostaglandin D2 in mice and humans.J Biol Chem2008
18285567Microsomal prostaglandin E synthase-1 deletion suppresses oxidative stress and angiotensin II-induced abdominal aortic aneurysm formation.Circulation2008
16397127Reduced thromboxane biosynthesis in carriers of toll-like receptor 4 polymorphisms in vivo.Blood2006
16973753Deletion of microsomal prostaglandin E synthase-1 augments prostacyclin and retards atherogenesis.Proc Natl Acad Sci U S A2006
16890573Heterogeneity in the suppression of platelet cyclooxygenase-1 activity by aspirin in coronary heart disease.Clin Pharmacol Ther2006
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Collaborators

Garret A FitzGerald
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 30
Tilo Grosser
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 9
Gregory R Grant
Perelman School of Medicine, University of Pennsylvania Philadelphia
Co-authored papers 7
Nicholas F Lahens
University of Pennsylvania.
Co-authored papers 6
Aalim M Weljie
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 4
Stuart C Sealfon
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Daniel J Rader
Co-authored papers 2
Jonathan Schug
University of Pennsylvania Perelman School of Medicine
Co-authored papers 2
Katalin Susztak
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 2
Krzysztof Laudanski
Mayo Clinic
Co-authored papers 2
Elizabeth W Karlson
Brigham and Women's Hospital
Co-authored papers 1
Wen Lin
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 1
Arjun Krishnan
Michigan State University
Co-authored papers 1
Daniel S Himmelstein
University of Pennsylvania
Co-authored papers 1
Valerian E Kagan
Center for Free Radical and Antioxidant Health, University of Pittsburgh
Co-authored papers 1
Julian L Griffin
Cambridge University
Co-authored papers 1
Kyle Bittinger
Children's Hospital of Philadelphia
Co-authored papers 1
Seth D Rhoades
University of Pennsylvania
Co-authored papers 1
Olga G Troyanskaya
Lewis-Sigler Institute for Integrative Genomics, Princeton University
Co-authored papers 1
Andrew V Kossenkov
The Wistar Institute
Co-authored papers 1
Miao He
Children's Hospital of Philadelphia
Co-authored papers 1
Amruta Naik
Children's Hospital of Philadelphia
Co-authored papers 1
Tao Wang
University of Texas Southwestern Medical Center
Co-authored papers 1
Casey S Greene
Co-authored papers 1
Ronan Lordan
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 1
Leslie J Crofford
Vanderbilt University School of Medicine
Co-authored papers 1
Ren?? A Zelaya
Geisel School of Medicine at Dartmouth
Co-authored papers 1
Casey S Greene
Dartmouth College Geisel School of Medicine, Princeton University, University of Colorado Anschutz Medical Campus, University of Pennsylvania Perelman School of Medicine
Co-authored papers 1
Ran Zhang
University of Wisconsin School of Medicine and Public Health
Co-authored papers 1
Allan I Pack
University of Pennsylvania Perelman School of Medicine
Co-authored papers 1
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