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Author Details

Giorgio Inghirami
Meyer Cancer Center, Weill Cornell Medicine and New York Presbyterian Hospital
1984
304
84
PMIDPaper TitleJournal TitlePublished Year
35981563Endothelial cell-leukemia interactions remodel drug responses, uncovering T-ALL vulnerabilities.Blood2023
37584198ETS1 phosphorylation at threonine 38 is associated with the cell of origin of diffuse large B cell lymphoma and sustains the growth of tumour cells.Br J Haematol2023
37563685Lysin (K)-specific demethylase 1 inhibition enhances proteasome inhibitor response and overcomes drug resistance in multiple myeloma.Exp Hematol Oncol2023
37381763Long non-coding RNA mitophagy and ALK-negative anaplastic lymphoma-associated transcript: a novel regulator of mitophagy in T-cell lymphoma.Haematologica2023
37379367Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma.Sci Transl Med2023
36996787Primary Effusion Lymphoma in an HIV-Negative Patient with Chronic Myeloid Leukemia Treated with Dasatinib.Pathobiology2023
36845713Tyrosine kinases in nodal peripheral T-cell lymphomas.Front Oncol2023
36468984In Vivo Modeling of CLL Transformation to Richter Syndrome Reveals Convergent Evolutionary Paths and Therapeutic Vulnerabilities.Blood Cancer Discov2023
36796016Multicenter phase 2 study of oral azacitidine (CC-486) plus CHOP as initial treatment for PTCL.Blood2023
36525970Hyaluronan driven by epithelial aPKC deficiency remodels the microenvironment and creates a vulnerability in mesenchymal colorectal cancer.Cancer Cell2023
36928381Combinatorial treatment rescues tumour-microenvironment-mediated attenuation of MALT1 inhibitors in B-cell lymphomas.Nat Mater2023
34162177Characterization of GECPAR, a noncoding RNA that regulates the transcriptional program of diffuse large B-cell lymphoma.Haematologica2022
35839444Gene Expression Signatures for the Accurate Diagnosis of Peripheral T-Cell Lymphoma Entities in the Routine Clinical Practice.J Clin Oncol2022
35364013Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction.Cell Stem Cell2022
36001803Genomic profiling for clinical decision making in lymphoid neoplasms.Blood2022
36083035Characteristics and clinical outcomes of patients with ALK-positive anaplastic large cell lymphoma: Report from the prospective international T-cell lymphoma project.Hematol Oncol2022
36282572A FOXO1-dependent transcription network is a targetable vulnerability of mantle cell lymphomas.J Clin Invest2022
35095900Metabolic and Immune Markers for Precise Monitoring of COVID-19 Severity and Treatment.Front Immunol2022
34551074Successful treatment and integrated genomic analysis of an infant with FIP1L1-RARA fusion-associated myeloid neoplasm.Blood Adv2022
32327503Whole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target.Haematologica2021
33541860Clinical and Biological Subtypes of B-cell Lymphoma Revealed by Microenvironmental Signatures.Cancer Discov2021
33928261<i>FYN-TRAF3IP2</i> induces NF-κB signaling-driven peripheral T cell lymphoma.Nat Cancer2021
33928032Cytoskeleton Dynamics in Peripheral T Cell Lymphomas: An Intricate Network Sustaining Lymphomagenesis.Front Oncol2021
33504766The DNA-helicase HELLS drives ALK<sup>-</sup> ALCL proliferation by the transcriptional control of a cytokinesis-related program.Cell Death Dis2021
33861502In Vivo and Ex Vivo Patient-Derived Tumor Xenograft Models of Lymphoma for Drug Discovery.Curr Protoc2021
34527579Comparison of Multiple Clinical Testing Modalities for Assessment of NPM1-Mutant AML.Front Oncol2021
34581268Mutation analysis links angioimmunoblastic T-cell lymphoma to clonal hematopoiesis and smoking.Elife2021
34479963Oncogenic HSP90 Facilitates Metabolic Alterations in Aggressive B-cell Lymphomas.Cancer Res2021
34653242A phase 2 biomarker-driven study of ruxolitinib demonstrates effectiveness of JAK/STAT targeting in T-cell lymphomas.Blood2021
34560002PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis.Mol Cell2021
34292324Outcomes and prognostic factors in angioimmunoblastic T-cell lymphoma: final report from the international T-cell Project.Blood2021
34050029Genetic mechanisms of HLA-I loss and immune escape in diffuse large B cell lymphoma.Proc Natl Acad Sci U S A2021
33316635Kinomic profiling of tumour xenografts derived from patients with non-small cell lung cancer confirms their fidelity and reveals potentially actionable pathways.Eur J Cancer2021
32785655Identification of MALT1 feedback mechanisms enables rational design of potent antilymphoma regimens for ABC-DLBCL.Blood2021
31028364Whole exome sequencing reveals mutations in FAT1 tumor suppressor gene clinically impacting on peripheral T-cell lymphoma not otherwise specified.Mod Pathol2020
31968251Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer.Cell Rep2020
32051557Multiparametric in situ imaging of NPM1-mutated acute myeloid leukemia reveals prognostically-relevant features of the marrow microenvironment.Mod Pathol2020
32105608Survival outcomes of patients with extranodal natural-killer T-cell lymphoma: a prospective cohort study from the international T-cell Project.Lancet Haematol2020
31915197Selective Inhibition of HDAC3 Targets Synthetic Vulnerabilities and Activates Immune Surveillance in Lymphoma.Cancer Discov2020
33361110Profiling of immune dysfunction in COVID-19 patients allows early prediction of disease progression.Life Sci Alliance2020
32665700Correction: Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma.Leukemia2020
33002132T follicular helper phenotype predicts response to histone deacetylase inhibitors in relapsed/refractory peripheral T-cell lymphoma.Blood Adv2020
32935114Longitudinal immune profiling of mild and severe COVID-19 reveals innate and adaptive immune dysfunction and provides an early prediction tool for clinical progression.medRxiv2020
32753663Selective dysregulation of ROCK2 activity promotes aberrant transcriptional networks in ABC diffuse large B-cell lymphoma.Sci Rep2020
32667883Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531.Elife2020
32249838Peripheral T cell lymphomas: from the bench to the clinic.Nat Rev Cancer2020
32123306The novel lncRNA BlackMamba controls the neoplastic phenotype of ALK<sup>-</sup> anaplastic large cell lymphoma by regulating the DNA helicase HELLS.Leukemia2020
32203470Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia.Nat Genet2020
32560455A Novel JAK1 Mutant Breast Implant-Associated Anaplastic Large Cell Lymphoma Patient-Derived Xenograft Fostering Pre-Clinical Discoveries.Cancers (Basel)2020
32483360Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring.Nat Med2020
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Collaborators

Meyer Cancer Center
Co-authored papers 20
Institute for Cancer Genetics, Columbia University
Co-authored papers 19
Co-authored papers 16
Columbia University Vagelos College of Physicians and Surgeons
Co-authored papers 16
Sapienza University.
Co-authored papers 10
Merck & Co.
Co-authored papers 9
Candiolo Cancer Institute, Fondazione del Piemonte per l'Oncologia (FPO) - IRCCS
Co-authored papers 8
Columbia University
Co-authored papers 7
Institute for Biomedical Research August Pi I Sunyer
Co-authored papers 5
University of British Columbia
Co-authored papers 5
Dana-Farber Cancer Institute
Co-authored papers 4
Dana-Farber Cancer Institute
Co-authored papers 4
Brigham and Women's Hospital and Harvard Medical School
Co-authored papers 4
Weill Cornell Medicine and New York Presbyterian Hospital
Co-authored papers 4
NYU Grossman School of Medicine
Co-authored papers 4
Case Western Reserve University
Co-authored papers 4
Dana-Farber Cancer Institute
Co-authored papers 4
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 4
Candiolo Cancer Institute - FPO IRCCS
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
Harvard Medical School
Co-authored papers 3
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Candiolo Cancer Institute - FPO IRCCS
Co-authored papers 3
Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna
Co-authored papers 3
National Cancer Institute, National Institutes of Health
Co-authored papers 3
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NewYork-Presbyterian Hospital
Co-authored papers 3
Columbia University
Co-authored papers 3
VILLUM Center for Bioanalytical Sciences, University of Southern Denmark
Co-authored papers 3