Author details

Full Name

Vahram Haroutunian

Affiliation

ORCID

Career Start Year

1977

Papers

371

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
34165562	Erratum to: Comprehensive Gene Expression Analysis Detects Global Reduction of Proteasome Subunits in Schizophrenia.	Schizophrenia Bulletin	2023
37886514	The neuronal chromatin landscape in adult schizophrenia brains is linked to early fetal development.	Res Sq	2023
38076956	Long-read RNA-seq atlas of novel microglia isoforms elucidates disease-associated genetic regulation of splicing.	medRxiv	2023
37873320	The neuronal chromatin landscape in adult schizophrenia brains is linked to early fetal development.	medRxiv	2023
37684260	Multi-omic atlas of the parahippocampal gyrus in Alzheimer's disease.	Sci Data	2023
37090548	Genetic regulation of cell-type specific chromatin accessibility shapes the etiology of brain diseases.	bioRxiv	2023
37340466	Sex specific molecular networks and key drivers of Alzheimer's disease.	Mol Neurodegener	2023
37205331	Efficient differential expression analysis of large-scale single cell transcriptomics data using dreamlet.	Res Sq	2023
37079947	Lower levels of cortical [H]pirenzepine binding to postmortem tissue defines a sub-group of older people with schizophrenia with less severe cognitive deficits.		2023
36811307	Genome-wide methylomic regulation of multiscale gene networks in Alzheimer's disease.	Alzheimers Dement	2023
37005977	Up-Regulation of S100 Gene Family in Brain Samples of a Subgroup of Individuals with Schizophrenia: Meta-analysis.		2023
36798327	ApoE Alzheimer's Disease AÎ²-amyloid plaque morphology varies according to APOE isotype.	Res Sq	2023
36993704	Efficient differential expression analysis of large-scale single cell transcriptomics data using dreamlet.	bioRxiv	2023
34758195	Engagement of vascular early response genes typifies mild cognitive impairment.	Alzheimer's and Dementia	2022
35396580	Mapping genomic loci implicates genes and synaptic biology in schizophrenia.	Nature	2022
36171428	The three-dimensional landscape of cortical chromatin accessibility in Alzheimer's disease.	Nat Neurosci	2022
35501530	Differential genetic associations and expression of PAPST1/SLC35B2 in bipolar disorder and schizophrenia.	Journal of Neural Transmission	2022
35931864	Genetics of the human microglia regulome refines Alzheimer's disease risk loci.	Nat Genet	2022
35332326	Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains.	Nat Neurosci	2022
34918867	Whole genome sequencing-based copy number variations reveal novel pathways and targets in Alzheimer's disease.	Alzheimers Dement	2022
35041991	Human apolipoprotein E isoforms are differentially sialylated and the sialic acid moiety in ApoE2 attenuates ApoE2-AÎ² interaction and AÎ² fibrillation.	Neurobiology of Disease	2022
35236988	FSH blockade improves cognition in mice with Alzheimer's disease.	Nature	2022
35115731	Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level.	Nat Neurosci	2022
35013160	Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease.	Nat Commun	2022
34757788	A brain proteomic signature of incipient Alzheimer's disease in young <i>APOE</i> Îµ4 carriers identifies novel drug targets.	Sci Adv	2021
33905124	The human brain acetylome reveals that decreased acetylation of mitochondrial proteins associates with Alzheimer's disease.	Journal of Neurochemistry	2021
33683887	Global Profiling of Lysine Accessibility to Evaluate Protein Structure Changes in Alzheimer's Disease.	J Am Soc Mass Spectrom	2021
34112773	A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex.	Nat Commun	2021
34272489	Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity.	Molecular Psychiatry	2021
33523961	Molecular subtyping of Alzheimer's disease using RNA sequencing data reveals novel mechanisms and targets.	Sci Adv	2021
33724354	Progressive Multifocal Leukoencephalopathy in a Patient With Progressive Multiple Sclerosis Treated With Ocrelizumab Monotherapy.	JAMA Neurology	2021
33827706	Streamlined alpha-synuclein RT-QuIC assay for various biospecimens in Parkinson's disease and dementia with Lewy bodies.	Acta Neuropathol Commun	2021
34353357	Predictors of cognitive impairment in primary age-related tauopathy: an autopsy study.	Acta Neuropathol Commun	2021
33141894	Comprehensive Gene Expression Analysis Detects Global Reduction of Proteasome Subunits in Schizophrenia.	Schizophrenia Bulletin	2021
33238137	Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease.	Neuron	2021
32632205	MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer's disease pathogenesis.	Mol Psychiatry	2021
33070392	Molecular signature of extracellular matrix pathology in schizophrenia.	European Journal of Neuroscience	2021
34924992	Transcriptomic Changes Highly Similar to Alzheimer's Disease Are Observed in a Subpopulation of Individuals During Normal Brain Aging.	Front Aging Neurosci	2021
32770063	Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease.	Nat Commun	2020
32376074	Gene expression meta-analysis reveals the down-regulation of three GABA receptor subunits in the superior temporal gyrus of patients with schizophrenia.	Schizophrenia Research	2020
32024511	Comparison of brain connectomes by MRI and genomics and its implication in Alzheimer's disease.	BMC Med	2020
31677937	C99 selectively accumulates in vulnerable neurons in Alzheimer's disease.	Alzheimer's and Dementia	2020
32396777	Human Brain and Serum Advanced Glycation End Products are Highly Correlated: Preliminary Results of Their Role in Alzheimer Disease and Type 2 Diabetes.	Endocrine Practice	2020
32284590	Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation.	Nat Med	2020
31926610	Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression.	Neuron	2020
32437656	Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression.	Neuron	2020
32711556	Integrated analysis of ultra-deep proteomes in cortex, cerebrospinal fluid and serum reveals a mitochondrial signature in Alzheimer's disease.	Mol Neurodegener	2020
32948549	Role of cumulative biological risk in mediating socioeconomic disparities in cognitive function in the elderly: a mediation analysis.	BMJ Open	2020
30770886	Artificial intelligence in neuropathology: deep learning-based assessment of tauopathy.	Laboratory Investigation	2019
31607776	Is Alzheimer disease a failure of mobilizing immune defense? Lessons from cognitively fit oldest-old.	Dialogues in Clinical Neuroscience	2019