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Author Details

Tianyuan Wang
National Institute of Environmental Health Sciences, National Institutes of Health
2005
53
21
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36328762Multiple tissue-specific epigenetic alterations regulate persistent gene expression changes following developmental DES exposure in mouse reproductive tissues.Epigenetics2023
37528140TRIM28 modulates nuclear receptor signaling to regulate uterine function.Nat Commun2023
37664846The NR2F2-HAND2 signaling axis regulates progesterone actions in the uterus at early pregnancy.Front Endocrinol (Lausanne)2023
36120506Myometrial progesterone receptor determines a transcription program for uterine remodeling and contractions during pregnancy.PNAS Nexus2022
35536696Pulmonary Function and Blood DNA Methylation: A Multiancestry Epigenome-Wide Association Meta-analysis.Am J Respir Crit Care Med2022
35681455Progesterone Signaling in Endometrial Epithelial Organoids.Cells2022
35895287The Estrogen Receptor α Cistrome in Human Endometrium and Epithelial Organoids.Endocrinology2022
33159991CASK, APBA1, and STXBP1 collaborate during insulin secretion.Mol Cell Endocrinol2021
35423963Single point mutations can potentially enhance infectivity of SARS-CoV-2 revealed by <i>in silico</i> affinity maturation and SPR assay.RSC Adv2021
33707208Progesterone receptor isoform B regulates the <i>Oxtr</i>-<i>Plcl2</i>-<i>Trpc3</i> pathway to suppress uterine contractility.Proc Natl Acad Sci U S A2021
34934913The role of epithelial progesterone receptor isoforms in embryo implantation.iScience2021
34899830Structural Equation Modeling of In silico Perturbations.Front Genet2021
34819359Correction: A brain-specific PGC1a fusion transcript affects gene expression and behavioral outcomes in mice.Life Sci Alliance2021
34516295Epigenome-Wide DNA Methylation and Pesticide Use in the Agricultural Lung Health Study.Environ Health Perspect2021
34649938A brain-specific <i>pgc1</i>α fusion transcript affects gene expression and behavioural outcomes in mice.Life Sci Alliance2021
34058008Poor Endometrial Proliferation After Clomiphene is Associated With Altered Estrogen Action.J Clin Endocrinol Metab2021
32235736Heme, A Metabolic Sensor, Directly Regulates the Activity of the KDM4 Histone Demethylase Family and Their Interactions with Partner Proteins.Cells2020
31908010Dynamic transcriptome, accessible genome, and PGR cistrome profiles in the human myometrium.FASEB J2020
31665330Human Endometrial Transcriptome and Progesterone Receptor Cistrome Reveal Important Pathways and Epithelial Regulators.J Clin Endocrinol Metab2020
33188567Cask methylation involved in the injury of insulin secretion function caused by interleukin1-β.J Cell Mol Med2020
33048843WNK1 regulates uterine homeostasis and its ability to support pregnancy.JCI Insight2020
32937126Single Nucleotide Resolution Analysis Reveals Pervasive, Long-Lasting DNA Methylation Changes by Developmental Exposure to a Mitochondrial Toxicant.Cell Rep2020
33023986Constitutive expression of progesterone receptor isoforms promotes the development of hormone-dependent ovarian neoplasms.Sci Signal2020
32360420Cytokine storm intervention in the early stages of COVID-19 pneumonia.Cytokine Growth Factor Rev2020
32242619ESR1 Mutations Associated With Estrogen Insensitivity Syndrome Change Conformation of Ligand-Receptor Complex and Altered Transcriptome Profile.Endocrinology2020
32381493Epigenome-wide association study of DNA methylation and adult asthma in the Agricultural Lung Health Study.Eur Respir J2020
31089135JNK<sup>1/2</sup> represses Lkb<sup>1</sup>-deficiency-induced lung squamous cell carcinoma progression.Nat Commun2019
31248101ERBB2 Regulates MED24 during Cancer Progression in Mice with <i>Pten</i> and <i>Smad4</i> Deletion in the Pulmonary Epithelium.Cells2019
30737248Mitochondrial acetyl-CoA reversibly regulates locus-specific histone acetylation and gene expression.Life Sci Alliance2019
29126261Heme promotes transcriptional and demethylase activities of Gis1, a member of the histone demethylase JMJD2/KDM4 family.Nucleic Acids Res2018
30061609Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.Nat Commun2018
30452456FOXO1 regulates uterine epithelial integrity and progesterone receptor expression critical for embryo implantation.PLoS Genet2018
30356064SOX17 regulates uterine epithelial-stromal cross-talk acting via a distal enhancer upstream of Ihh.Nat Commun2018
29648668Widespread enhancer activation via ERα mediates estrogen response in vivo during uterine development.Nucleic Acids Res2018
29668680Mitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation.PLoS Biol2018
29666266DNA methylation and transcriptome aberrations mediated by ERα in mouse seminal vesicles following developmental DES exposure.Proc Natl Acad Sci U S A2018
28203817Decreased epithelial progesterone receptor A at the window of receptivity is required for preparation of the endometrium for embryo attachment.Biol Reprod2017
26725009TCA Cycle and Mitochondrial Membrane Potential Are Necessary for Diverse Biological Functions.Mol Cell2016
27783953A Gata2-Dependent Transcription Network Regulates Uterine Progesterone Responsiveness and Endometrial Function.Cell Rep2016
27415830A Novel Analytical Strategy to Identify Fusion Transcripts between Repetitive Elements and Protein Coding-Exons Using RNA-Seq.PLoS One2016
26861414Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns.Nat Commun2016
27040690DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis.Am J Hum Genet2016
23912340Epigenetic regulation of COL15A1 in smooth muscle cell replicative aging and atherosclerosis.Hum Mol Genet2013
24069155A minimal set of tissue-specific hypomethylated CpGs constitute epigenetic signatures of developmental programming.PLoS One2013
21298289Polymorphic variants in tenascin-C (TNC) are associated with atherosclerosis and coronary artery disease.Hum Genet2011
21602498Expanded methyl-sensitive cut counting reveals hypomethylation as an epigenetic state that highlights functional sequences of the genome.Proc Natl Acad Sci U S A2011
21750106Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity.Genome Res2011
20421368Aging-related atherosclerosis is exacerbated by arterial expression of tumor necrosis factor receptor-1: evidence from mouse models and human association studies.Hum Mol Genet2010
19403457A general integrative genomic feature transcription factor binding site prediction method applied to analysis of USF1 binding in cardiovascular disease.Hum Genomics2009
20031585Analysis of complex disease association and linkage studies using the University of California Santa Cruz Genome Browser.Circ Cardiovasc Genet2009
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Collaborators

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National Institute of Environmental Health Sciences
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Duke University School of Medicine
Co-authored papers 5
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Duke Molecular Physiology Institute, Duke University School of Medicine
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Duke Molecular Physiology Institute Durham NC.
Co-authored papers 3
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University of North Carolina at Chapel Hill
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University of Washington Medical Center
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Harvard T.H. Chan School of Public Health
Co-authored papers 2
School of Public Health, Imperial College London
Co-authored papers 2
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Mailman School of Public Health, Columbia University
Co-authored papers 2
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and Blood Institute, National Institutes of Health
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University of California san francisco
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