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Author Details

Elizabeth M Jaffee
Convergence Institute, Johns Hopkins University
1985
312
91
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35941803Profiling of syngeneic mouse HCC tumor models as a framework to understand anti-PD-1 sensitive tumor microenvironments.Hepatology2023
37904980Immune landscape of tertiary lymphoid structures in hepatocellular carcinoma (HCC) treated with neoadjuvant immune checkpoint blockade.bioRxiv2023
37745323Digitize your Biology! Modeling multicellular systems through interpretable cell behavior.bioRxiv2023
37645761Informing virtual clinical trials of hepatocellular carcinoma with spatial multi-omics analysis of a human neoadjuvant immunotherapy clinical trial.bioRxiv2023
37723590Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence.Genome Med2023
37350948Colorectal cancer in patients of advanced age is associated with increased incidence of <i>BRAF</i> p.V600E mutation and mismatch repair deficiency.Front Oncol2023
36947820Multiomics Empowers Predictive Pancreatic Cancer Immunotherapy.J Immunol2023
37080163Uncovering the spatial landscape of molecular interactions within the tumor microenvironment through latent spaces.Cell Syst2023
37339979A platform trial of neoadjuvant and adjuvant antitumor vaccination alone or in combination with PD-1 antagonist and CD137 agonist antibodies in patients with resectable pancreatic adenocarcinoma.Nat Commun2023
37363104Updates on radiotherapy-immunotherapy combinations: Proceedings of 6<sup>th</sup> annual ImmunoRad conference.Oncoimmunology2023
37067233Achieving the Goals of the Cancer Moonshot Requires Progress against All Cancers.Cancer Discov2023
37067199Converging on a Cure: The Roads to Predictive Immunotherapy.Cancer Discov2023
36919699HMGA1 induces FGF19 to drive pancreatic carcinogenesis and stroma formation.J Clin Invest2023
36712023Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence.bioRxiv2023
35201318Entinostat Decreases Immune Suppression to Promote Antitumor Responses in a HER2+ Breast Tumor Microenvironment.Cancer Immunol Res2022
35841152Engineered bispecific antibodies targeting the interleukin-6 and -8 receptors potently inhibit cancer cell migration and tumor metastasis.Mol Ther2022
35650435Stromal changes in the aged lung induce an emergence from melanoma dormancy.Nature2022
35398344Pancreatic Cancer: Pathogenesis, Screening, Diagnosis, and Treatment.Gastroenterology2022
35363262Precision Medicine in Pancreatic Cancer: Patient-Derived Organoid Pharmacotyping Is a Predictive Biomarker of Clinical Treatment Response.Clin Cancer Res2022
35487571Translational Cancer Research Priorities and the Role of Molecular Imaging: A Conversation Between Chi Van Dang, Elizabeth Jaffee, and David Mankoff.J Nucl Med2022
36439024A Random Forest Genomic Classifier for Tumor Agnostic Prediction of Response to Anti-PD1 Immunotherapy.Cancer Inform2022
36661655Solid Organ Transplantation Is Associated with an Increased Rate of Mismatch Repair Deficiency and PIK3CA Mutations in Colorectal Cancer.Curr Oncol2022
36214223Integrated T cell cytometry metrics for immune-monitoring applications in immunotherapy clinical trials.JCI Insight2022
36306792Multi-omic analyses of changes in the tumor microenvironment of pancreatic adenocarcinoma following neoadjuvant treatment with anti-PD-1 therapy.Cancer Cell2022
36112643Quantitative Spatial Profiling of Immune Populations in Pancreatic Ductal Adenocarcinoma Reveals Tumor Microenvironment Heterogeneity and Prognostic Biomarkers.Cancer Res2022
35289317Messenger RNA vaccines for cancer immunotherapy: progress promotes promise.J Clin Invest2022
35190728A framework for fibrolamellar carcinoma research and clinical trials.Nat Rev Gastroenterol Hepatol2022
35144882Shared genetic and epigenetic changes link aging and cancer.Trends Cell Biol2022
35174086Pancreatic Ductal Adenocarcinoma Cortical Mechanics and Clinical Implications.Front Oncol2022
33482124Cancer Moonshot 2.0.Lancet Oncol2021
33542081How Did We Get a COVID-19 Vaccine in Less Than 1 Year?Clin Cancer Res2021
33504579An Empirical Antigen Selection Method Identifies Neoantigens That Either Elicit Broad Antitumor T-cell Responses or Drive Tumor Growth.Cancer Discov2021
33727309Leukocyte Heterogeneity in Pancreatic Ductal Adenocarcinoma: Phenotypic and Spatial Features Associated with Clinical Outcome.Cancer Discov2021
33531075A feasibility study of combined epigenetic and vaccine therapy in advanced colorectal cancer with pharmacodynamic endpoint.Clin Epigenetics2021
33690223A global live cell barcoding approach for multiplexed mass cytometry profiling of mouse tumors.JCI Insight2021
34911778Macrophage-Targeting by CSF1/1R Blockade in Pancreatic Cancers.Cancer Res2021
35330848Forecasting cancer: from precision to predictive medicine.Med2021
35047458Translational Advances in Cancer Prevention Agent Development (TACPAD) Virtual Workshop on Immunomodulatory Agents: Report.J Cancer Prev2021
34554099Analysis of Population Differences in Digital Conversations About Cancer Clinical Trials: Advanced Data Mining and Extraction Study.JMIR Cancer2021
34788629Evaluating the impact of age on immune checkpoint therapy biomarkers.Cell Rep2021
34433020Evaluating the impact of age on immune checkpoint therapy biomarkers.Cell Rep2021
34376232Transfer learning between preclinical models and human tumors identifies a conserved NK cell activation signature in anti-CTLA-4 responsive tumors.Genome Med2021
34777919Implantation of a neoantigen-targeted hydrogel vaccine prevents recurrence of pancreatic adenocarcinoma after incomplete resection.Oncoimmunology2021
34625505IgE-Based Therapeutic Combination Enhances Antitumor Response in Preclinical Models of Pancreatic Cancer.Mol Cancer Ther2021
34508005Pharmacodynamic measures within tumors expose differential activity of PD(L)-1 antibody therapeutics.Proc Natl Acad Sci U S A2021
34389557Context-Dependent Immunomodulatory Effects of MEK Inhibition Are Enhanced with T-cell Agonist Therapy.Cancer Immunol Res2021
34479924Development of preclinical and clinical models for immune-related adverse events following checkpoint immunotherapy: a perspective from SITC and AACR.J Immunother Cancer2021
34796337Neoadjuvant Cabozantinib and Nivolumab Converts Locally Advanced HCC into Resectable Disease with Enhanced Antitumor Immunity.Nat Cancer2021
34329587From bench to bedside: Single-cell analysis for cancer immunotherapy.Cancer Cell2021
33985562Multi-omic profiling of lung and liver tumor microenvironments of metastatic pancreatic cancer reveals site-specific immune regulatory pathways.Genome Biol2021
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Collaborators

Elana J Fertig
Johns Hopkins University School of Medicine
Co-authored papers 30
Ludmila Danilova
Bloomberg-Kimmel Immunotherapy Institute, Johns Hopkins University School of Medicine
Co-authored papers 16
Anirban Maitra
The University of Texas MD Anderson Cancer Center
Co-authored papers 13
Tim F Greten
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 9
Genevieve L Stein-O'Brien
Johns Hopkins School of Medicine
Co-authored papers 9
Vered Stearns
Co-authored papers 9
Alex B Blair
Johns Hopkins University School of Medicine
Co-authored papers 7
Richard D Schulick
University of Colorado School of Medicine
Co-authored papers 7
Victor E Velculescu
Co-authored papers 5
Nancy E Davidson
Co-authored papers 5
Mary L Disis
University of Washington Medicine Cancer Vaccine Institute, University of Washington
Co-authored papers 5
Siân Jones
Co-authored papers 4
Bert Vogelstein
Co-authored papers 4
Donald W Parsons
Texas Children's Hospital
Co-authored papers 4
Jimmy C Lin
National Human Genome Research Institute, US National Institutes of Health
Co-authored papers 4
Giovanni Parmigiani
Dana Farber Cancer Institute.
Co-authored papers 4
Xiaosong Zhang
Co-authored papers 4
Ashani T Weeraratna
Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine
Co-authored papers 4
Kenneth W Kinzler
Co-authored papers 4
Antonio C Wolff
Co-authored papers 3
Elizabeth Garrett-Mayer
Center for Research and Analytics, American Society of Clinical Oncology
Co-authored papers 3
Rebecca J Leary
Co-authored papers 3
Antoni Ribas
University of California Los Angeles (university of california los angeles)
Co-authored papers 3
Jonathan W Simons
Co-authored papers 3
Sarah J Wheelan
National Human Genome Research Institute, National Institutes of Health
Co-authored papers 3
Chi V Dang
Johns Hopkins University School of Medicine
Co-authored papers 3
Firouzeh Korangy
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 3
Linda M S Resar
Johns Hopkins University School of Medicine
Co-authored papers 3
Byung Park
Oregon Health & Science University
Co-authored papers 2
William J Murphy
Co-authored papers 2
Release 1.2