Author details

Full Name

Orit Rozenblatt-Rosen

Affiliation

ORCID

Career Start Year

1998

Papers

115

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37425718	A cellular and spatial atlas of <i>TP53</i> -associated tissue remodeling in lung adenocarcinoma.	bioRxiv	2024
36797494	TACCO unifies annotation transfer and decomposition of cell identities for single-cell and spatial omics.	Nat Biotechnol	2023
36109685	Mostly natural sequencing-by-synthesis for scRNA-seq using Ultima sequencing.	Nat Biotechnol	2023
38076853	A deep lung cell atlas reveals cytokine-mediated lineage switching of a rare cell progenitor of the human airway epithelium.	bioRxiv	2023
37961084	Multi-modal skin atlas identifies a multicellular immune-stromal community associated with altered cornification and specific T cell expansion in atopic dermatitis.	bioRxiv	2023
37344597	B-cell-specific checkpoint molecules that regulate anti-tumour immunity.	Nature	2023
37336975	Multicellular communities are perturbed in the aging human brain and Alzheimer's disease.	Nat Neurosci	2023
36747789	Systematically characterizing the roles of E3-ligase family members in inflammatory responses with massively parallel Perturb-seq.	bioRxiv	2023
36993643	Inference of single cell profiles from histology stains with the Single-Cell omics from Histology Analysis Framework (SCHAF).	bioRxiv	2023
35058622	Massively parallel phenotyping of coding variants in cancer with Perturb-seq.	Nat Biotechnol	2022
35906236	Mouse fetal growth restriction through parental and fetal immune gene variation and intercellular communications cascade.	Nat Commun	2022
35902743	Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment.	Nat Genet	2022
35389781	Single-cell RNA-seq reveals cell type-specific molecular and genetic associations to lupus.	Science	2022
35803260	Tissue-resident memory and circulating T cells are early responders to pre-surgical cancer immunotherapy.	Cell	2022
35549429	Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function.	Science	2022
35482859	Stepwise-edited, human melanoma models reveal mutations' effect on tumor and microenvironment.	Science	2022
36324805	A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients.	bioRxiv	2022
36258042	Author Correction: Massively parallel phenotyping of coding variants in cancer with Perturb-seq.	Nat Biotechnol	2022
35313592	Functional analyses and single cell immunoprofiling uncover sex-specific differences in SARS-CoV2 immune memory development.	Res Sq	2022
34982959	Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function.	Immunity	2022
35275752	Tim-3 adapter protein Bat3 acts as an endogenous regulator of tolerogenic dendritic cell function.	Sci Immunol	2022
34792289	Single-Cell, Single-Nucleus, and Spatial RNA Sequencing of the Human Liver Identifies Cholangiocyte and Mesenchymal Heterogeneity.	Hepatol Commun	2022
35145087	SM-Omics is an automated platform for high-throughput spatial multi-omics.	Nat Commun	2022
34588693	Blood and immune development in human fetal bone marrow and Down syndrome.	Nature	2021
33592174	Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis.	Cell	2021
34015271	B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV.	Cell	2021
34108686	TIM-3 restrains anti-tumour immunity by regulating inflammasome activation.	Nature	2021
33509999	Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems.	Science	2021
33932339	A cellular and spatial map of the choroid plexus across brain ventricles and ages.	Cell	2021
33655247	A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2.	bioRxiv	2021
34087162	Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma.	Cancer Cell	2021
33649592	Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion.	Nat Genet	2021
33915569	COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets.	Nature	2021
33711272	Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma.	Cancer Cell	2021
33495604	Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma.	Nat Med	2021
34910928	Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps.	Cell	2021
34450029	Spatially organized multicellular immune hubs in human colorectal cancer.	Cell	2021
34594037	Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states.	Nat Genet	2021
34535664	A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery.	Nat Commun	2021
34534439	Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1<sup>+</sup> CD8<sup>+</sup> TÂ cells in tumor-draining lymph nodes.	Immunity	2021
34875227	Stem-like intestinal Th17 cells give rise to pathogenic effector TÂ cells during autoimmunity.	Cell	2021
32888429	The Human and Mouse Enteric Nervous System at Single-Cell Resolution.	Cell	2020
32304633	Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes.	Immunity	2020
32341567	Author Correction: Systematic comparison of single-cell and single-nucleus RNA-sequencing methods.	Nat Biotechnol	2020
32341560	Systematic comparison of single-cell and single-nucleus RNA-sequencing methods.	Nat Biotechnol	2020
32163288	National Cancer Institute Think-Tank Meeting Report on Proteomic Cartography and Biomarkers at the Single-Cell Level: Interrogation of Premalignant Lesions.	J Proteome Res	2020
32755564	A Distinct Transcriptional Program in Human CAR T Cells Bearing the 4-1BB Signaling Domain Revealed by scRNA-Seq.	Mol Ther	2020
33139715	Author Correction: Nuclei multiplexing with barcoded antibodies for single-nucleus genomics.	Nat Commun	2020
33238123	An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets.	Cell Rep	2020
33128048	Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity.	Nat Genet	2020