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Author Details

Laura Riva
Sanford Burnham Prebys Medical Discovery Institute
2003
48
22
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
34210369Prenatal maternal stress during the COVID-19 pandemic and infant regulatory capacity at 3 months: A longitudinal study.Dev Psychopathol2023
36388765Uncovering novel mutational signatures by <i>de novo</i> extraction with SigProfilerExtractor.Cell Genom2022
35809572Recognition of HIV-1 capsid by PQBP1 licenses an innate immune sensing of nascent HIV-1 DNA.Mol Cell2022
35502318Synthetic lethality-based prediction of anti-SARS-CoV-2 targets.iScience2022
33440148MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells.Cell Rep2021
33784499Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication.Cell Rep2021
33532779Genome-scale metabolic modeling reveals SARS-CoV-2-induced metabolic changes and antiviral targets.bioRxiv2021
34709707Genome-scale metabolic modeling reveals SARS-CoV-2-induced metabolic changes and antiviral targets.Mol Syst Biol2021
34556855Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy.Nat Microbiol2021
34468177The Compound SBI-0090799 Inhibits Zika Virus Infection by Blocking <i>De Novo</i> Formation of the Membranous Replication Compartment.J Virol2021
34545363Synthetic lethality-based prediction of anti-SARS-CoV-2 targets.bioRxiv2021
34155350The clinicopathologic spectrum and genomic landscape of de-/trans-differentiated melanoma.Mod Pathol2021
34083527Drug repurposing screens identify chemical entities for the development of COVID-19 interventions.Nat Commun2021
32511357A Large-scale Drug Repositioning Survey for SARS-CoV-2 Antivirals.bioRxiv2020
31959748Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice.Nat Commun2020
31776276Viral Determinants in H5N1 Influenza A Virus Enable Productive Infection of HeLa Cells.J Virol2020
33052331Clofazimine is a broad-spectrum coronavirus inhibitor that antagonizes SARS-CoV-2 replication in primary human cell culture and hamsters.Res Sq2020
32855398Multi-site clonality analysis uncovers pervasive heterogeneity across melanoma metastases.Nat Commun2020
32707573Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing.Nature2020
32989322The mutational signature profile of known and suspected human carcinogens in mice.Nat Genet2020
31216647Development of Personalized Therapeutic Strategies by Targeting Actionable Vulnerabilities in Metastatic and Chemotherapy-Resistant Breast Cancer PDXs.Cells2019
29985941No unexpected CRISPR-Cas9 off-target activity revealed by trio sequencing of gene-edited mice.PLoS Genet2018
35135136Precision Trial Drawer, a Computational Tool to Assist Planning of Genomics-Driven Trials in Oncology.JCO Precis Oncol2018
28025581PML-RARA-associated cooperating mutations belong to a transcriptional network that is deregulated in myeloid leukemias.Leukemia2017
28569218A knowledge-based framework for the discovery of cancer-predisposing variants using large-scale sequencing breast cancer data.Breast Cancer Res2017
28747664Mutations targeting the coagulation pathway are enriched in brain metastases.Sci Rep2017
26860319LowMACA: exploiting protein family analysis for the identification of rare driver mutations in cancer.BMC Bioinformatics2016
27779108RNAi screens identify CHD4 as an essential gene in breast cancer growth.Oncotarget2016
27320920In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer.Cell Rep2016
27179036In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype.Cancer Discov2016
25499761The hidden genomic landscape of acute myeloid leukemia: subclonal structure revealed by undetected mutations.Blood2015
26511446Peak shape clustering reveals biological insights.BMC Bioinformatics2015
25850996Whole exome sequencing identifies driver mutations in asymptomatic computed tomography-detected lung cancers with normal karyotype.Cancer Genet2015
25957348INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA- and 4sU-seq time course experiments.Bioinformatics2015
24658373Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups.Blood Cancer J2014
25690659DOTS-Finder: a comprehensive tool for assessing driver genes in cancer genomes.Genome Med2014
25311739The genomic and epigenomic landscapes of AML.Semin Hematol2014
24036946Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups.Blood Cancer J2013
22666660Genomics of acute myeloid leukemia: the next generation.Front Oncol2012
23293686Poly-glutamine expanded huntingtin dramatically alters the genome wide binding of HSF1.J Huntingtons Dis2012
19234470Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity.Nat Genet2009
19941827Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis.Mol Cell2009
15728662Skeletal muscle gene expression profiling in mitochondrial disorders.FASEB J2005
15034146Silencer elements as possible inhibitors of pseudoexon splicing.Nucleic Acids Res2004
15325254Over-representation of exonic splicing enhancers in human intronless genes suggests multiple functions in mRNA processing.Biochem Biophys Res Commun2004
15358987Effects of reboxetine on sleep and nocturnal cardiac autonomic activity in patients with dysthymia.J Psychopharmacol2004
14729831A locus on 15q15-15qter influences dyslexia: further support from a transmission/disequilibrium study in an Italian speaking population.J Med Genet2004
12727896Comparative analysis of vertebrate dystrophin loci indicate intron gigantism as a common feature.Genome Res2003
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Collaborators

The Scripps Research Institute
Co-authored papers 12
The Scripps Research Institute
Co-authored papers 10
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 8
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 8
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 6
Icahn School of Medicine at Mount Sinai
Co-authored papers 6
Wellcome Sanger Institute
Co-authored papers 6
National Cancer Institute
Co-authored papers 5
Michigan State University College of Human Medicine
Co-authored papers 4
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 4
University of California San Diego
Co-authored papers 4
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
University of Milan
Co-authored papers 3
Center for Genomic Science of , Istituto Italiano di Tecnologia (IIT)
Co-authored papers 3
University of California los angeles
Co-authored papers 3
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Co-authored papers 3
Northwestern University Feinberg School of Medicine
Co-authored papers 3
Moores Cancer Center, university of california san diego
Co-authored papers 3
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 2
Manchester Cancer Research Centre, University of Manchester
Co-authored papers 2
Wellcome Sanger Institute
Co-authored papers 2
University of Milano
Co-authored papers 2
National Cancer Institute, National Institutes of Health
Co-authored papers 2
The Scripps Research Institute
Co-authored papers 2
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
a division of The Scripps Research Institute La Jolla
Co-authored papers 2
Gladstone Institutes
Co-authored papers 2
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Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2