| 36533912 | Tyrosine Kinase Inhibitors Display Potent Activity against Cryptosporidium parvum. | Microbiol Spectr | 2023 |
| 37535741 | <i>Delftia tsuruhatensis</i> TC1 symbiont suppresses malaria transmission by anopheline mosquitoes. | Science | 2023 |
| 37565760 | Novel inhibitors that target bacterial virulence identified via HTS against intra-macrophage survival of <i>Shigella flexneri</i>. | mSphere | 2023 |
| 36602336 | Cyclic AMP-Mediated Inhibition of Cholesterol Catabolism in <i>Mycobacterium tuberculosis</i> by the Novel Drug Candidate GSK2556286. | Antimicrob Agents Chemother | 2023 |
| 35607978 | GSK2556286 Is a Novel Antitubercular Drug Candidate Effective <i>In Vivo</i> with the Potential To Shorten Tuberculosis Treatment. | Antimicrob Agents Chemother | 2022 |
| 35507672 | The small-molecule SMARt751 reverses <i>Mycobacterium tuberculosis</i> resistance to ethionamide in acute and chronic mouse models of tuberculosis. | Sci Transl Med | 2022 |
| 34534310 | Tebipenem as an oral alternative for the treatment of typhoid caused by XDR Salmonella Typhi. | J Antimicrob Chemother | 2021 |
| 33909975 | Fighting <i>Shigella</i> by Blocking Its Disease-Causing Toxin. | J Med Chem | 2021 |
| 33740373 | Repurposing Infectious Disease Hits as Anti-<i>Cryptosporidium</i> Leads. | ACS Infect Dis | 2021 |
| 34471283 | Tres Cantos Open Lab: celebrating a decade of innovation in collaboration to combat endemic infectious diseases. | Nat Rev Drug Discov | 2021 |
| 32342688 | Optimization of Hydantoins as Potent Antimycobacterial Decaprenylphosphoryl-β-d-Ribose Oxidase (DprE1) Inhibitors. | J Med Chem | 2020 |
| 32275415 | MymA Bioactivated Thioalkylbenzoxazole Prodrug Family Active against <i>Mycobacterium tuberculosis</i>. | J Med Chem | 2020 |
| 31620228 | Novel Pyrazole-Containing Compounds Active against <i>Mycobacterium tuberculosis</i>. | ACS Med Chem Lett | 2019 |
| 31850398 | An open toolkit for tracking open science partnership implementation and impact. | Gates Open Res | 2019 |
| 29335214 | In vivo potent BM635 analogue with improved drug-like properties. | Eur J Med Chem | 2018 |
| 30140040 | Identification and characterization of aspartyl-tRNA synthetase inhibitors against Mycobacterium tuberculosis by an integrated whole-cell target-based approach. | Sci Rep | 2018 |
| 30194385 | Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1. | Sci Rep | 2018 |
| 30004092 | Author Correction: Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening. | Nat Commun | 2018 |
| 30500189 | Identification and Profiling of Hydantoins-A Novel Class of Potent Antimycobacterial DprE1 Inhibitors. | J Med Chem | 2018 |
| 29500372 | Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets. | Sci Rep | 2018 |
| 29632076 | The antibiotic cyclomarin blocks arginine-phosphate-induced millisecond dynamics in the N-terminal domain of ClpC1 from <i>Mycobacterium tuberculosis</i>. | J Biol Chem | 2018 |
| 29661879 | Accelerating Early Antituberculosis Drug Discovery by Creating Mycobacterial Indicator Strains That Predict Mode of Action. | Antimicrob Agents Chemother | 2018 |
| 29706526 | Synthesis, antimycobacterial activity and influence on mycobacterial InhA and PknB of 12-membered cyclodepsipeptides. | Bioorg Med Chem | 2018 |
| 29453370 | A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK. | Sci Rep | 2018 |
| 27704782 | Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis. | ACS Infect Dis | 2017 |
| 28475832 | A Phenotypic Based Target Screening Approach Delivers New Antitubercular CTP Synthetase Inhibitors. | ACS Infect Dis | 2017 |
| 28423019 | Design, synthesis and structure-activity relationship study of wollamide B; a new potential anti TB agent. | PLoS One | 2017 |
| 29148755 | Novel Antitubercular 6-Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure-Activity Relationship and Target Identification Studies. | J Med Chem | 2017 |
| 29018348 | Target Identification of <i>Mycobacterium tuberculosis</i> Phenotypic Hits Using a Concerted Chemogenomic, Biophysical, and Structural Approach. | Front Pharmacol | 2017 |
| 28842600 | Inhibiting mycobacterial tryptophan synthase by targeting the inter-subunit interface. | Sci Rep | 2017 |
| 28714473 | Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening. | Nat Commun | 2017 |
| 27939618 | Pharmaceutical salt of BM635 with improved bioavailability. | Eur J Pharm Sci | 2017 |
| 26900657 | New direct inhibitors of InhA with antimycobacterial activity based on a tetrahydropyran scaffold. | Eur J Med Chem | 2016 |
| 27982051 | Novel inhibitors of Mycobacterium tuberculosis GuaB2 identified by a target based high-throughput phenotypic screen. | Sci Rep | 2016 |
| 27581223 | Identification of KasA as the cellular target of an anti-tubercular scaffold. | Nat Commun | 2016 |
| 27678056 | Repurposing clinically approved cephalosporins for tuberculosis therapy. | Sci Rep | 2016 |
| 27428438 | Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor. | EBioMedicine | 2016 |
| 27121350 | A new piperidinol derivative targeting mycolic acid transport in Mycobacterium abscessus. | Mol Microbiol | 2016 |
| 27348630 | Searching for New Leads for Tuberculosis: Design, Synthesis, and Biological Evaluation of Novel 2-Quinolin-4-yloxyacetamides. | J Med Chem | 2016 |
| 27571973 | THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria. | Nat Microbiol | 2016 |
| 27433841 | β-Lactams against Tuberculosis--New Trick for an Old Dog? | N Engl J Med | 2016 |
| 27020099 | Open Lab as a source of hits and leads against tuberculosis, malaria and kinetoplastid diseases. | Nat Rev Drug Discov | 2016 |
| 26934341 | N-Benzyl-4-((heteroaryl)methyl)benzamides: A New Class of Direct NADH-Dependent 2-trans Enoyl-Acyl Carrier Protein Reductase (InhA) Inhibitors with Antitubercular Activity. | ChemMedChem | 2016 |
| 25348525 | High-content screening technology combined with a human granuloma model as a new approach to evaluate the activities of drugs against Mycobacterium tuberculosis. | Antimicrob Agents Chemother | 2015 |
| 26449457 | Non-absorbable mesoporous silica for the development of protein sequestration therapies. | Biochem Biophys Res Commun | 2015 |
| 26642067 | Release of 50 new, drug-like compounds and their computational target predictions for open source anti-tubercular drug discovery. | PLoS One | 2015 |
| 27623058 | Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase. | ACS Infect Dis | 2015 |
| 26771003 | A Focused Screen Identifies Antifolates with Activity on Mycobacterium tuberculosis. | ACS Infect Dis | 2015 |
| 26149997 | Hydrolysis of clavulanate by Mycobacterium tuberculosis β-lactamase BlaC harboring a canonical SDN motif. | Antimicrob Agents Chemother | 2015 |
| 26222445 | Carbamoyl Triazoles, Known Serine Protease Inhibitors, Are a Potent New Class of Antimalarials. | J Med Chem | 2015 |