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| 36538511 | Discovery of the First Lactate Dehydrogenase Proteolysis Targeting Chimera Degrader for the Treatment of Pancreatic Cancer. | J Med Chem | 2023 |
| 38019706 | Discovery of Potent and Selective WDR5 Proteolysis Targeting Chimeras as Potential Therapeutics for Pancreatic Cancer. | J Med Chem | 2023 |
| 37774414 | Methylated Nucleotide-Based Proteolysis-Targeting Chimera Enables Targeted Degradation of Methyl-CpG-Binding Protein 2. | J Am Chem Soc | 2023 |
| 37858336 | Non-canonical function of histone methyltransferase G9a in the translational regulation of chronic inflammation. | Cell Chem Biol | 2023 |
| 37028406 | Activation of hypothalamic-enhanced adult-born neurons restores cognitive and affective function in Alzheimer's disease. | | 2023 |
| 37141574 | Telomere Targeting Chimera Enables Targeted Destruction of Telomeric Repeat-Binding Factor Proteins. | J Am Chem Soc | 2023 |
| 36448571 | Bridged Proteolysis Targeting Chimera (PROTAC) Enables Degradation of Undruggable Targets. | J Am Chem Soc | 2022 |
| 35969644 | Nonlytic cellular release of hepatitis A virus requires dual capsid recruitment of the ESCRT-associated Bro1 domain proteins HD-PTP and ALIX. | PLoS Pathog | 2022 |
| 35837138 | Targeting Triple-Negative Breast Cancer by a Novel Proteolysis Targeting Chimera Degrader of Enhancer of Zeste Homolog 2. | ACS Pharmacol Transl Sci | 2022 |
| 36286484 | Nonlytic Quasi-Enveloped Hepatovirus Release Is Facilitated by pX Protein Interaction with the E3 Ubiquitin Ligase ITCH. | Journal of Virology | 2022 |
| 36347944 | Histone H3 proline 16 hydroxylation regulates mammalian gene expression. | Nat Genet | 2022 |
| 36197750 | Novel Allosteric Inhibitor-Derived AKT Proteolysis Targeting Chimeras (PROTACs) Enable Potent and Selective AKT Degradation in KRAS/BRAF Mutant Cells. | J Med Chem | 2022 |
| 35786952 | TF-DUBTACs Stabilize Tumor Suppressor Transcription Factors. | J Am Chem Soc | 2022 |
| 34855399 | Design, Synthesis, and Evaluation of Potent, Selective, and Bioavailable AKT Kinase Degraders. | J Med Chem | 2021 |
| 33644773 | Protocol for proteogenomic dissection of intronic splicing enhancer interactome for prediction of individualized cancer prognosis. | STAR Protocols | 2021 |
| 33854241 | Author Correction: AIM2 in regulatory T cells restrains autoimmune diseases. | Nature | 2021 |
| 34100597 | TF-PROTACs Enable Targeted Degradation of Transcription Factors. | J Am Chem Soc | 2021 |
| 33505023 | AIM2 in regulatory T cells restrains autoimmune diseases. | Nature | 2021 |
| 34301793 | AKT Degradation Selectively Inhibits the Growth of PI3K/PTEN Pathway-Mutant Cancers with Wild-Type KRAS and BRAF by Destabilizing Aurora Kinase B. | Cancer Discov | 2021 |
| 34520194 | Harnessing the E3 Ligase KEAP1 for Targeted Protein Degradation. | J Am Chem Soc | 2021 |
| 34795874 | Discovery and Development of Cyclic Peptide Inhibitors of CIB1. | ACS Medicinal Chemistry Letters | 2021 |
| 34568836 | Distinct CDK6 complexes determine tumor cell response to CDK4/6 inhibitors and degraders. | Nat Cancer | 2021 |
| 32787082 | Discovery of First-in-Class Protein Arginine Methyltransferase 5 (PRMT5) Degraders. | J Med Chem | 2020 |
| 31895569 | Discovery of Potent and Selective Epidermal Growth Factor Receptor (EGFR) Bifunctional Small-Molecule Degraders. | J Med Chem | 2020 |
| 31810986 | TBK1 Is a Synthetic Lethal Target in Cancer with Loss. | Cancer Discovery | 2020 |
| 33355139 | CRL4[DCAF1/VprBP] E3 ubiquitin ligase controls ribosome biogenesis, cell proliferation, and development. | Sci Adv | 2020 |
| 33236014 | Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics. | bioRxiv | 2020 |
| 33284613 | Potent and Selective Mitogen-Activated Protein Kinase Kinase 1/2 (MEK1/2) Heterobifunctional Small-molecule Degraders. | J Med Chem | 2020 |
| 31146747 | Novel secretome-to-transcriptome integrated or secreto-transcriptomic approach to reveal liquid biopsy biomarkers for predicting individualized prognosis of breast cancer patients. | BMC Medical Genomics | 2019 |
| 31730343 | Discovery of a First-in-Class Mitogen-Activated Protein Kinase Kinase 1/2 Degrader. | J Med Chem | 2019 |
| 31729379 | Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer. | Nat Commun | 2019 |
| 31336272 | Multi-omic Dissection of Oncogenically Active Epiproteomes Identifies Drivers of Proliferative and Invasive Breast Tumors. | iScience | 2019 |
| 29503206 | Novel RNA-Affinity Proteogenomics Dissects Tumor Heterogeneity for Revealing Personalized Markers in Precision Prognosis of Cancer. | Cell Chemical Biology | 2018 |
| 30026228 | VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma. | Science | 2018 |
| 30446383 | RAS P21 Protein Activator 3 (RASA3) Specifically Promotes Pathogenic T Helper 17 Cell Generation by Repressing T-Helper-2-Cell-Biased Programs. | Immunity | 2018 |
| 28440318 | Corrigendum: Proteogenomic integration reveals therapeutic targets in breast cancer xenografts. | Nat Commun | 2017 |
| 28348404 | Proteogenomic integration reveals therapeutic targets in breast cancer xenografts. | Nat Commun | 2017 |
| 28854366 | The Deacetylase HDAC6 Mediates Endogenous Neuritic Tau Pathology. | Cell Reports | 2017 |
| 28490497 | Protein composition of the hepatitis A virus quasi-envelope. | Proceedings of the National Academy of Sciences of the United States of America | 2017 |
| 26631509 | An Analysis of the Sensitivity of Proteogenomic Mapping of Somatic Mutations and Novel Splicing Events in Cancer. | Mol Cell Proteomics | 2016 |
| 27112199 | Proteomic dissection of LPS-inducible, PHF8-dependent secretome reveals novel roles of PHF8 in TLR4-induced acute inflammation and T cell proliferation. | Scientific Reports | 2016 |
| 26598639 | QuantFusion: Novel Unified Methodology for Enhanced Coverage and Precision in Quantifying Global Proteomic Changes in Whole Tissues. | Molecular and Cellular Proteomics | 2016 |
| 26119999 | Non-canonical Bromodomain within DNA-PKcs Promotes DNA Damage Response and Radioresistance through Recognizing an IR-Induced Acetyl-Lysine on H2AX. | Chem Biol | 2015 |
| 23448259 | Whole human genome proteogenomic mapping for ENCODE cell line data: identifying protein-coding regions. | BMC Genomics | 2013 |
| 23434512 | Protein phosphatase 2A catalytic subunit α plays a MyD88-dependent, central role in the gene-specific regulation of endotoxin tolerance. | Cell Reports | 2013 |
| 23030679 | GOFAST: an integrated approach for efficient and comprehensive membrane proteome analysis. | Analytical Chemistry | 2012 |
| 22833098 | BCLAF1 is a radiation-induced H2AX-interacting partner involved in γH2AX-mediated regulation of apoptosis and DNA repair. | Cell Death and Disease | 2012 |
| 22955977 | Long noncoding RNAs are rarely translated in two human cell lines. | Genome Res | 2012 |
| 20696126 | An optimized magnetite microparticle-based phosphopeptide enrichment strategy for identifying multiple phosphorylation sites in an immunoprecipitated protein. | Analytical Biochemistry | 2011 |
| 21220426 | Unambiguous characterization of site-specific phosphorylation of leucine-rich repeat Fli-I-interacting protein 2 (LRRFIP2) in Toll-like receptor 4 (TLR4)-mediated signaling. | Journal of Biological Chemistry | 2011 |