|
| 36791402 | Residue-Level Characterization of Antibody Binding Epitopes Using Carbene Chemical Footprinting. | Anal Chem | 2023 |
| 37675979 | Biophysical characterization of PVR family interactions and therapeutic antibody recognition to TIGIT. | MAbs | 2023 |
| 35241687 | Humanization of a strategic CD3 epitope enables evaluation of clinical T-cell engagers in a fully immunocompetent in vivo model. | Sci Rep | 2022 |
| 35344340 | Impact of Drug Conjugation on Thermal and Metabolic Stabilities of Aglycosylated and <i>N</i>-Glycosylated Antibodies. | Bioconjug Chem | 2022 |
| 35981087 | Preclinical Characterization of Relatlimab, a Human LAG-3-Blocking Antibody, Alone or in Combination with Nivolumab. | Cancer Immunol Res | 2022 |
| 35192429 | Improved therapeutic index of an acidic pH-selective antibody. | MAbs | 2022 |
| 35316223 | Tim-3 mediates T cell trogocytosis to limit antitumor immunity. | J Clin Invest | 2022 |
| 34258584 | Tumor burden limits bispecific antibody efficacy through T cell exhaustion averted by concurrent cytotoxic therapy. | Blood Cancer Discov | 2021 |
| 33654081 | Structures of mouse and human GITR-GITRL complexes reveal unique TNF superfamily interactions. | Nat Commun | 2021 |
| 33750099 | Automated and Faster Affinity Capture Method for Biotransformation Assessment of Site-Specific Antibody Drug Conjugates. | Anal Chem | 2021 |
| 34854675 | High-Throughput Surface Plasmon Resonance Biosensors for Identifying Diverse Therapeutic Monoclonal Antibodies. | Anal Chem | 2021 |
| 34595996 | Antibody blockade of CD96 by distinct molecular mechanisms. | MAbs | 2021 |
| 32178516 | High-Throughput Platform to Identify Antibody Conjugation Sites from Antibody-Drug Conjugate Libraries. | Bioconjug Chem | 2020 |
| 31860282 | Universal Affinity Capture Liquid Chromatography-Mass Spectrometry Assay for Evaluation of Biotransformation of Site-Specific Antibody Drug Conjugates in Preclinical Studies. | Anal Chem | 2020 |
| 31856660 | Design and characterization of mouse IgG1 and IgG2a bispecific antibodies for use in syngeneic models. | MAbs | 2020 |
| 32639723 | Integrated Approach for Characterizing Bispecific Antibody/Antigens Complexes and Mapping Binding Epitopes with SEC/MALS, Native Mass Spectrometry, and Protein Footprinting. | Anal Chem | 2020 |
| 30792442 | Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugates. | Sci Rep | 2019 |
| 31700121 | Author Correction: Targeting CLDN18.2 by CD3 Bispecific and ADC Modalities for the Treatments of Gastric and Pancreatic Cancer. | Sci Rep | 2019 |
| 31182754 | Targeting CLDN18.2 by CD3 Bispecific and ADC Modalities for the Treatments of Gastric and Pancreatic Cancer. | Sci Rep | 2019 |
| 31434693 | Preclinical Efficacy and Safety Comparison of CD3 Bispecific and ADC Modalities Targeting BCMA for the Treatment of Multiple Myeloma. | Mol Cancer Ther | 2019 |
| 29714014 | Epitope Mapping Using Yeast Display and Next Generation Sequencing. | Methods Mol Biol | 2018 |
| 30323890 | RN765C, a low affinity EGFR antibody drug conjugate with potent anti-tumor activity in preclinical solid tumor models. | Oncotarget | 2018 |
| 28060885 | Antibodies Targeting Closely Adjacent or Minimally Overlapping Epitopes Can Displace One Another. | PLoS One | 2017 |
| 28151644 | Improved Lysosomal Trafficking Can Modulate the Potency of Antibody Drug Conjugates. | Bioconjug Chem | 2017 |
| 26944918 | Molecular Basis of Valine-Citrulline-PABC Linker Instability in Site-Specific ADCs and Its Mitigation by Linker Design. | Mol Cancer Ther | 2016 |
| 26481561 | Production of soluble and active microbial transglutaminase in Escherichia coli for site-specific antibody drug conjugation. | Protein Sci | 2016 |
| 26426339 | Hemoglobin oxidation at functional amino acid residues during routine storage of red blood cells. | Transfusion | 2016 |
| 27582525 | RN927C, a Site-Specific Trop-2 Antibody-Drug Conjugate (ADC) with Enhanced Stability, Is Highly Efficacious in Preclinical Solid Tumor Models. | Mol Cancer Ther | 2016 |
| 27857134 | Germline-encoded neutralization of a Staphylococcus aureus virulence factor by the human antibody repertoire. | Nat Commun | 2016 |
| 27329693 | The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels. | Nat Commun | 2016 |
| 27129281 | Modulation of P2X3 and P2X2/3 Receptors by Monoclonal Antibodies. | J Biol Chem | 2016 |
| 27129258 | Engineering Highly Potent and Selective Microproteins against Nav1.7 Sodium Channel for Treatment of Pain. | J Biol Chem | 2016 |
| 25284753 | Precise and efficient antibody epitope determination through library design, yeast display and next-generation sequencing. | J Mol Biol | 2015 |
| 26161543 | Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy. | PLoS One | 2015 |
| 26154005 | Site-specific conjugation improves therapeutic index of antibody drug conjugates with high drug loading. | Nat Biotechnol | 2015 |
| 25658443 | The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity. | MAbs | 2015 |
| 25643134 | Effect of attachment site on stability of cleavable antibody drug conjugates. | Bioconjug Chem | 2015 |
| 24423618 | World Antibody-Drug Conjugate Summit, October 15-16, 2013, San Francisco, CA. | MAbs | 2014 |
| 24694238 | Versatility of microbial transglutaminase. | Bioconjug Chem | 2014 |
| 24359082 | Mass spectrometric characterization of transglutaminase based site-specific antibody-drug conjugates. | Bioconjug Chem | 2014 |
| 23438745 | Location matters: site of conjugation modulates stability and pharmacokinetics of antibody drug conjugates. | Chem Biol | 2013 |
| 23416200 | Mechanism of action and in vivo efficacy of a human-derived antibody against Staphylococcus aureus α-hemolysin. | J Mol Biol | 2013 |
| 22019884 | Proprotein convertase substilisin/kexin type 9 antagonism reduces low-density lipoprotein cholesterol in statin-treated hypercholesterolemic nonhuman primates. | J Pharmacol Exp Ther | 2012 |
| 23093611 | A method for integrative structure determination of protein-protein complexes. | Bioinformatics | 2012 |
| 22483106 | Fabs enable single particle cryoEM studies of small proteins. | Structure | 2012 |
| 22543237 | Generating bispecific human IgG1 and IgG2 antibodies from any antibody pair. | J Mol Biol | 2012 |
| 22294692 | Increasing serum half-life and extending cholesterol lowering in vivo by engineering antibody with pH-sensitive binding to PCSK9. | J Biol Chem | 2012 |
| 20837146 | Three-dimensional molecular modeling with single molecule FRET. | J Struct Biol | 2011 |
| 21928778 | Post-translational modifications and lipid binding profile of insect cell-expressed full-length mammalian synaptotagmin 1. | Biochemistry | 2011 |
| 20378544 | The longin SNARE VAMP7/TI-VAMP adopts a closed conformation. | J Biol Chem | 2010 |