Author details

Full Name

Jian Yan

Affiliation

ORCID

Career Start Year

2009

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36566265	Simultaneous profiling of histone modifications and DNA methylation via nanopore sequencing.		2022
36097552	The highly conserved RNA-binding specificity of nucleocapsid protein facilitates the identification of drugs with broad anti-coronavirus activity.	Computational and Structural Biotechnology Journal	2022
36778047	Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines.	Cell Genom	2022
33505025	Systematic analysis of binding of transcription factors to noncoding variants.	Nature	2021
33479524	Author Correction: CRISPR-assisted detection of RNA-protein interactions in living cells.	Nature Methods	2021
33779544	An atlas of the binding specificities of transcription factors in directs prediction of novel regulators in virulence.	eLife	2021
33720298	Directed Evolution of an Enhanced POU Reprogramming Factor for Cell Fate Engineering.	Mol Biol Evol	2021
33009392	A compendium of DNA-binding specificities of transcription factors in Pseudomonas syringae.	Nature Communications	2020
32572232	CRISPR-assisted detection of RNA-protein interactions in living cells.	Nature Methods	2020
31064983	Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk.	Nat Commun	2019
31724731	Super-enhancers in transcriptional regulation and genome organization.	Nucleic Acids Research	2019
29313530	Histone H3 lysine 4 monomethylation modulates long-range chromatin interactions at enhancers.	Cell Res	2018
29497152	Histone H3 lysine 4 monomethylation modulates long-range chromatin interactions at enhancers.	Cell Res	2018
28195176	The non-coding variant rs1800734 enhances DCLK3 expression through long-range interaction and promotes colorectal cancer progression.	Nat Commun	2017
28583252	Mice deficient of <i>Myc</i> super-enhancer region reveal differential control mechanism between normal and pathological growth.	Elife	2017
28473536	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	Science	2017
28215080	A Scalable Epitope Tagging Approach for High Throughput ChIP-Seq Analysis.	ACS Synth Biol	2017
27331016	ERBB3-rs2292239 as primary type 1 diabetes association locus among non-HLA genes in Chinese.	Meta Gene	2016
24390282	A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding.	Nat Genet	2014
23332764	DNA-binding specificities of human transcription factors.	Cell	2013
23953112	Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites.	Cell	2013
23118011	Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors.	Science	2012
22429595	Characterization of the colorectal cancer-associated enhancer MYC-335 at 8q24: the role of rs67491583.	Cancer Genet	2012
21868628	MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas.	Science	2011
20378718	Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities.	Genome Res	2010
20517297	Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo.	EMBO J	2010
19561604	The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling.	Nat Genet	2009