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Author Details

Edward D Lewandowski
1987
81
33
PMIDPaper TitleJournal TitlePublished Year
36927960RIP140 deficiency enhances cardiac fuel metabolism and protects mice from heart failure.J Clin Invest2023
37138801Western Diet Causes Heart Failure With Reduced Ejection Fraction and Metabolic Shifts After Diastolic Dysfunction and Novel Cardiac Lipid Derangements.2023
37451081Metabolic flux in the driver's seat during cardiac health and disease.2023
35958686Short-Chain Carbon Sources: Exploiting Pleiotropic Effects for Heart Failure Therapy.JACC: Basic to Translational Science2022
33601938Short-Chain Fatty Acids Outpace Ketone Oxidation in the Failing Heart.Circulation2021
33106689Mitochondrial pyruvate carriers are required for myocardial stress adaptation.Nature Metabolism2020
33208925Publisher Correction: Mitochondrial pyruvate carriers are required for myocardial stress adaptation.Nature Metabolism2020
33284649Sensing Danger: A New Player in the Innate Immune Response During Cardiac Pressure Overload.Circulation2020
30909726Preservation of Acyl Coenzyme A Attenuates Pathological and Metabolic Cardiac Remodeling Through Selective Lipid Trafficking.Circulation2019
31682528Response by Lewandowski et al to Letter Regarding Article, "Preservation of Acyl Coenzyme A Attenuates Pathological and Metabolic Cardiac Remodeling Through Selective Lipid Trafficking".Circulation2019
29386187Enhanced Redox State and Efficiency of Glucose Oxidation With miR Based Suppression of Maladaptive NADPH-Dependent Malic Enzyme 1 Expression in Hypertrophied Hearts.Circulation Research2018
30012703Deciphering the Role of Lipid Droplets in Cardiovascular Disease: A Report From the 2017 National Heart, Lung, and Blood Institute Workshop.Circulation2018
28130336Peroxisome proliferator-activated receptor-α expression induces alterations in cardiac myofilaments in a pressure-overload model of hypertrophy.American Journal of Physiology - Heart and Circulatory Physiology2017
28404627Multiphasic Regulation of Systemic and Peripheral Organ Metabolic Responses to Cardiac Hypertrophy.Circulation: Heart Failure2017
28743802Enhancing natriuretic peptide signaling in adipose tissue, but not in muscle, protects against diet-induced obesity and insulin resistance.Science Signaling2017
26819376The Failing Heart Relies on Ketone Bodies as a Fuel.Circulation2016
27151515Role of Mitochondrial Oxidative Stress in Glucose Tolerance, Insulin Resistance, and Cardiac Diastolic Dysfunction.Journal of the American Heart Association2016
26749052Cardiac MR elastography of the mouse: Initial results.Magnetic Resonance in Medicine2016
27012580Assessing Cardiac Metabolism: A Scientific Statement From the American Heart Association.Circ Res2016
26995156Acyl CoA synthetase-1 links facilitated long chain fatty acid uptake to intracellular metabolic trafficking differently in hearts of male versus female mice.Journal of Molecular and Cellular Cardiology2016
26993578Triacylglycerol turnover in the failing heart.2016
25199499Resolving confounding enrichment kinetics due to overlapping resonance signals from 13C-enriched long chain fatty acid oxidation and uptake within intact hearts.Magnetic Resonance in Medicine2015
25795713A novel pharmacological strategy by PTEN inhibition for improving metabolic resuscitation and survival after mouse cardiac arrest.American Journal of Physiology - Heart and Circulatory Physiology2015
25450611Impaired cytosolic NADH shuttling and elevated UCP3 contribute to inefficient citric acid cycle flux support of postischemic cardiac work in diabetic hearts.Journal of Molecular and Cellular Cardiology2015
25424393Metabolic efficiency promotes protection from pressure overload in hearts expressing slow skeletal troponin I.Circulation: Heart Failure2015
26465331Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome.PLoS One2015
24526677Matrix revisited: mechanisms linking energy substrate metabolism to the function of the heart.Circulation Research2014
25266948Dietary fat supply to failing hearts determines dynamic lipid signaling for nuclear receptor activation and oxidation of stored triglyceride.Circulation2014
25035131Is the therapeutic window for mitochondrial ROS half-open or half-closed? Mixing mitophagic metaphors.Circulation Research2014
23099442Multiphasic triacylglycerol dynamics in the intact heart during acute in vivo overexpression of CD36.Journal of Lipid Research2013
22982985Acute liver carnitine palmitoyltransferase I overexpression recapitulates reduced palmitate oxidation of cardiac hypertrophy.Circulation Research2013
22178085Sexual dimorphism in cardiac triacylglyceride dynamics in mice on long term caloric restriction.Journal of Molecular and Cellular Cardiology2012
22974418In vivo, cardiac-specific knockdown of a target protein, malic enzyme-1, in rat via adenoviral delivery of DNA for non-native miRNA.Current Gene Therapy2012
21640727Expression of slow skeletal TnI in adult mouse hearts confers metabolic protection to ischemia.J Mol Cell Cardiol2011
21835931Second window of preconditioning normalizes palmitate use for oxidation and improves function during low-flow ischaemia.Cardiovascular Research2011
20457796Imaging myocardial metabolic remodeling.2010
20837747Early impairment of transmural principal strains in the left ventricular wall after short-term, high-fat feeding of mice predisposed to cardiac steatosis.Circulation: Cardiovascular Imaging2010
20522803Preferential oxidation of triacylglyceride-derived fatty acids in heart is augmented by the nuclear receptor PPARalpha.Circ Res2010
19213957Substrate-enzyme competition attenuates upregulated anaplerotic flux through malic enzyme in hypertrophied rat heart and restores triacylglyceride content: attenuating upregulated anaplerosis in hypertrophy.Circulation Research2009
19744494SERCA1 expression enhances the metabolic efficiency of improved contractility in post-ischemic heart.Journal of Molecular and Cellular Cardiology2009
18487436The transcriptional coactivator PGC-1alpha is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis.Am J Physiol Heart Circ Physiol2008
17965277Principal strain changes precede ventricular wall thinning during transition to heart failure in a mouse model of dilated cardiomyopathy.American Journal of Physiology - Heart and Circulatory Physiology2008
18155232The absence of endogenous lipid oxidation in early stage heart failure exposes limits in lipid storage and turnover.Journal of Molecular and Cellular Cardiology2008
18066748Improved cardiac tagging resolution at ultra-high magnetic field elucidates transmural differences in principal strain in the mouse heart and reduced stretch in dilated cardiomyopathy.Journal of Cardiovascular Magnetic Resonance2007
17404155Recruitment of compensatory pathways to sustain oxidative flux with reduced carnitine palmitoyltransferase I activity characterizes inefficiency in energy metabolism in hypertrophied hearts.Circulation2007
17229809Recruitment of NADH shuttling in pressure-overloaded and hypertrophic rat hearts.American Journal of Physiology - Cell Physiology2007
16234271Accelerated triacylglycerol turnover kinetics in hearts of diabetic rats include evidence for compartmented lipid storage.Am J Physiol Endocrinol Metab2006
15789062Efficient, cardiac-specific adenoviral gene transfer in rat heart by isolated retrograde perfusion in vivo.Gene Therapy2005
14751856Limited transfer of cytosolic NADH into mitochondria at high cardiac workload.American Journal of Physiology - Heart and Circulatory Physiology2004
15522269Gender-specific proteomic alterations in glycolytic and mitochondrial pathways in aging monkey hearts.Journal of Molecular and Cellular Cardiology2004
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