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Author Details

Sean R Collins
University of California davis
2003
55
34
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36227545Modeling Subcellular Protein Recruitment Dynamics for Synthetic Biology.Methods Mol Biol2023
37147680Vangl-dependent Wnt/planar cell polarity signaling mediates collective breast carcinoma motility and distant metastasis.Breast Cancer Res2023
37336284A complex of Wnt/planar cell polarity signaling components Vangl1 and Fzd7 drives glioblastoma multiforme malignant properties.Cancer Lett2023
36827986Leading edge competition promotes context-dependent responses to receptor inputs to resolve directional dilemmas in neutrophil migration.Cell Syst2023
36821624Flagella-driven motility is a target of human Paneth cell defensin activity.PLoS Pathog2023
34964841WASP integrates substrate topology and cell polarity to guide neutrophil migration.J Cell Biol2022
35568027Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes.Cell Host Microbe2022
34785640Directional reorientation of migrating neutrophils is limited by suppression of receptor input signaling at the cell rear through myosin II activity.Nat Commun2021
33843200Optimized iLID Membrane Anchors for Local Optogenetic Protein Recruitment.ACS Synth Biol2021
33502312SUMO is a pervasive regulator of meiosis.Elife2021
34785668Optogenetic control of receptors reveals distinct roles for actin- and Cdc42-dependent negative signals in chemotactic signal processing.Nat Commun2021
32694631Decoding GEFs of animated cells.Nat Chem Biol2020
31014479Efficient Front-Rear Coupling in Neutrophil Chemotaxis by Dynamic Myosin II Localization.Dev Cell2019
30397336Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.Nat Genet2018
29974859"Rho"ing a Cellular Boat with Rearward Membrane Flow.Dev Cell2018
30068296A map of gene expression in neutrophil-like cell lines.BMC Genomics2018
30062406Parallel High-Resolution Imaging of Leukocyte Chemotaxis Under Agarose with Rho-Family GTPase Biosensors.Methods Mol Biol2018
26689677Locally excitable Cdc42 signals steer cells during chemotaxis.Nat Cell Biol2016
26836307Waves of actin and microtubule polymerization drive microtubule-based transport and neurite growth before single axon formation.Elife2016
25683721Systematic Discovery of Human Gene Function and Principles of Modular Organization through Phylogenetic Profiling.Cell Rep2015
25908733Using light to shape chemical gradients for parallel and automated analysis of chemotaxis.Mol Syst Biol2015
24442241Set5 and Set1 cooperate to repress gene expression at telomeres and retrotransposons.Epigenetics2014
25498153Dynamic recruitment of the curvature-sensitive protein ArhGAP44 to nanoscale membrane deformations limits exploratory filopodia initiation in neurons.Elife2014
22681890Hierarchical modularity and the evolution of genetic interactomes across species.Mol Cell2012
22682253Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions.Cell2012
21288721Evolutionary origins of STIM1 and STIM2 within ancient Ca2+ signaling systems.Trends Cell Biol2011
21987634A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria.J Cell Biol2011
21673141Site-specific acetylation mark on an essential chromatin-remodeling complex promotes resistance to replication stress.Proc Natl Acad Sci U S A2011
20182505Orm family proteins mediate sphingolipid homeostasis.Nature2010
20844529Cell biology: A sensor for calcium uptake.Nature2010
20946812Quantitative genetic interaction mapping using the E-MAP approach.Methods Enzymol2010
19217416Calcium flickers lighting the way in chemotaxis?Dev Cell2009
19953683From information to knowledge: new technologies for defining gene function.Nat Methods2009
19325107Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum.Science2009
19556461An ER-mitochondria tethering complex revealed by a synthetic biology screen.Science2009
19176519A complex-based reconstruction of the Saccharomyces cerevisiae interactome.Mol Cell Proteomics2009
19269370Functional organization of the S. cerevisiae phosphorylation network.Cell2009
18223646Small-molecule aggregates inhibit amyloid polymerization.Nat Chem Biol2008
19160513High-throughput, quantitative analyses of genetic interactions in E. coli.Nat Methods2008
18818364Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast.Science2008
19061648A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing.Mol Cell2008
18622397A comprehensive strategy enabling high-resolution functional analysis of the yeast genome.Nat Methods2008
17200106Toward a comprehensive atlas of the physical interactome of Saccharomyces cerevisiae.Mol Cell Proteomics2007
17693258Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses.Cell2007
17314980Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map.Nature2007
17389396CCR4/NOT complex associates with the proteasome and regulates histone methylation.Proc Natl Acad Sci U S A2007
17389874Backup without redundancy: genetic interactions reveal the cost of duplicate gene loss.Mol Syst Biol2007
16554755Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.Nature2006
17101447Quantitative genetic analysis in Saccharomyces cerevisiae using epistatic miniarray profiles (E-MAPs) and its application to chromatin functions.Methods2006
16810177The physical basis of how prion conformations determine strain phenotypes.Nature2006
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Collaborators

Jonathan S Weissman
Whitehead Institute for Biomedical Research
Co-authored papers 25
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 22
Maya Schuldiner
The Weizmann Institute of Science
Co-authored papers 10
Tobias Meyer
Co-authored papers 9
Michael Shales
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 8
Jack F Greenblatt
College Street, University of Toronto
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University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 5
Gerard Cagney
Conway Institute of Biomedical and Biomolecular Sciences, University College Dublin
Co-authored papers 4
Thanuja Punna
Co-authored papers 3
Michael-Christopher Keogh
EpiCypher Inc.
Co-authored papers 3
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University of California San Diego
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Natalie J Thompson
Co-authored papers 3
Patrick Kemmeren
Princess Maxima Center for Pediatric Oncology
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Andrew Emili
Boston University School of Medicine, Boston University
Co-authored papers 3
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University of California San Francisco
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University of Toronto
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University of California San Francisco
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Dorothea Fiedler
Leibniz Forschungsinstitut fur Molekulare Pharmakologie (FMP)
Co-authored papers 2
Candido J Ingles
Miguel Hernandez University of Elche.
Co-authored papers 2
Hongjing Qu
Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 2
Frank C P Holstege
Princess Maxima Center for Pediatric Oncology
Co-authored papers 2
Ashby J Morrison
Stanford University
Co-authored papers 2
Peter Walter
University of California san francisco
Co-authored papers 2
Brenda J Andrews
University of Toronto
Co-authored papers 2
Daphne Koller
Stanford University
Co-authored papers 2
Christine Guthrie
University of California san francisco
Co-authored papers 2
Jan Ihmels
University of California san francisco
Co-authored papers 2
Brian D Strahl
University of North Carolina
Co-authored papers 2
Sourav Bandyopadhyay
University of California San Francisco
Co-authored papers 2
Timothy R Hughes
University of Toronto
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Release 1.2