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Author Details

Noel Southall
National Center for Advancing Translational Sciences, National Institutes of Health
2002
171
43
PMIDPaper TitleJournal TitlePublished Year
37938539Validation of a Natural Language Machine Learning Model for Safety Literature Surveillance.Drug Saf2024
37938539Validation of a Natural Language Machine Learning Model for Safety Literature Surveillance.Drug Saf2024
36307650Pandemic vaccines: a formidable challenge for pharmacovigilance.Nat Rev Drug Discov2023
36307650Pandemic vaccines: a formidable challenge for pharmacovigilance.Nat Rev Drug Discov2023
34759309Clinical development times for innovative drugs.Nat Rev Drug Discov2022
36049119Real-Time Cellular Thermal Shift Assay to Monitor Target Engagement.ACS Chem Biol2022
35696646Discovery and Optimization of Pyrrolopyrimidine Derivatives as Selective Disruptors of the Perinucleolar Compartment, a Marker of Tumor Progression toward Metastasis.J Med Chem2022
36333465Discovery of small molecule agonists of the Relaxin Family Peptide Receptor 2.Commun Biol2022
36065186Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction.iScience2022
35611543Progress toward a universal biomedical data translator.Clin Transl Sci2022
36253497Discovery of small molecule inhibitors that effectively disrupt IQGAP1-Cdc42 interaction in breast cancer cells.Sci Rep2022
35399514c-Abl Activation Linked to Autophagy-Lysosomal Dysfunction Contributes to Neurological Impairment in Niemann-Pick Type A Disease.Front Cell Dev Biol2022
35239443Discovery of a functionally selective ghrelin receptor (GHSR<sub>1a</sub>) ligand for modulating brain dopamine.Proc Natl Acad Sci U S A2022
35182735Defining clinical outcome pathways.Drug Discov Today2022
35119255High-Throughput Cellular Thermal Shift Assay Using Acoustic Transfer of Protein Lysates.ACS Chem Biol2022
34759309Clinical development times for innovative drugs.Nat Rev Drug Discov2022
34648031NCATS Inxight Drugs: a comprehensive and curated portal for translational research.Nucleic Acids Res2022
35611543Progress toward a universal biomedical data translator.Clin Transl Sci2022
35399514c-Abl Activation Linked to Autophagy-Lysosomal Dysfunction Contributes to Neurological Impairment in Niemann-Pick Type A Disease.Front Cell Dev Biol2022
35696646Discovery and Optimization of Pyrrolopyrimidine Derivatives as Selective Disruptors of the Perinucleolar Compartment, a Marker of Tumor Progression toward Metastasis.J Med Chem2022
36333465Discovery of small molecule agonists of the Relaxin Family Peptide Receptor 2.Commun Biol2022
36065186Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction.iScience2022
36253497Discovery of small molecule inhibitors that effectively disrupt IQGAP1-Cdc42 interaction in breast cancer cells.Sci Rep2022
36049119Real-Time Cellular Thermal Shift Assay to Monitor Target Engagement.ACS Chem Biol2022
35182735Defining clinical outcome pathways.Drug Discov Today2022
35119255High-Throughput Cellular Thermal Shift Assay Using Acoustic Transfer of Protein Lysates.ACS Chem Biol2022
35239443Discovery of a functionally selective ghrelin receptor (GHSR<sub>1a</sub>) ligand for modulating brain dopamine.Proc Natl Acad Sci U S A2022
34648031NCATS Inxight Drugs: a comprehensive and curated portal for translational research.Nucleic Acids Res2022
33156327TCRD and Pharos 2021: mining the human proteome for disease biology.Nucleic Acids Res2021
34242083Erratum: CATMoS: Collaborative Acute Toxicity Modeling Suite.Environ Health Perspect2021
34176369Validating ADME QSAR Models Using Marketed Drugs.SLAS Discov2021
34075120Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells.Sci Rep2021
33731741A high-throughput screening to identify small molecules that suppress huntingtin promoter activity or activate huntingtin-antisense promoter activity.Sci Rep2021
33929906CATMoS: Collaborative Acute Toxicity Modeling Suite.Environ Health Perspect2021
34184537Discovery and Optimization of a 4-Aminopiperidine Scaffold for Inhibition of Hepatitis C Virus Assembly.J Med Chem2021
33156327TCRD and Pharos 2021: mining the human proteome for disease biology.Nucleic Acids Res2021
33137173Global Substance Registration System: consistent scientific descriptions for substances related to health.Nucleic Acids Res2021
34647794Erratum: CATMoS: Collaborative Acute Toxicity Modeling Suite.Environ Health Perspect2021
33731741A high-throughput screening to identify small molecules that suppress huntingtin promoter activity or activate huntingtin-antisense promoter activity.Sci Rep2021
33929906CATMoS: Collaborative Acute Toxicity Modeling Suite.Environ Health Perspect2021
34647794Erratum: CATMoS: Collaborative Acute Toxicity Modeling Suite.Environ Health Perspect2021
34184537Discovery and Optimization of a 4-Aminopiperidine Scaffold for Inhibition of Hepatitis C Virus Assembly.J Med Chem2021
34075120Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells.Sci Rep2021
34242083Erratum: CATMoS: Collaborative Acute Toxicity Modeling Suite.Environ Health Perspect2021
34176369Validating ADME QSAR Models Using Marketed Drugs.SLAS Discov2021
33137173Global Substance Registration System: consistent scientific descriptions for substances related to health.Nucleic Acids Res2021
32191456Validation and Characterization of Five Distinct Novel Inhibitors of Human Cytomegalovirus.J Med Chem2020
32144388Synaptamide activates the adhesion GPCR GPR110 (ADGRF1) through GAIN domain binding.Commun Biol2020
32191456Validation and Characterization of Five Distinct Novel Inhibitors of Human Cytomegalovirus.J Med Chem2020
32128386Small-molecule activation of lysosomal TRP channels ameliorates Duchenne muscular dystrophy in mouse models.Sci Adv2020
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Collaborators

National Institutes of Health, National Center for Advancing Translational Sciences
Co-authored papers 57
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Co-authored papers 53
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Expert Systems Inc.
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University of New Mexico School of Medicine
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Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
Co-authored papers 4
Center for Cancer Research, National Cancer Institute
Co-authored papers 4
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 4
National Institute of Environmental Health Sciences
Co-authored papers 4
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 4
Salish Kootenai College
Co-authored papers 4
Kangwon National University College of Medicine
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