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Author Details

Hediye Erdjument-Bromage
Neuroscience Institute, NYU Grossman School of Medicine
1984
286
130
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
38031883Proteomic profiling of interferon-responsive reactive astrocytes in rodent and human.Glia2024
36798364Modulation of GPR133 (ADGRD1) Signaling by its Intracellular Interaction Partner Extended Synaptotagmin 1 (ESYT1).bioRxiv2023
37690688Cardiolipin prolongs the lifetimes of respiratory proteins in Drosophila flight muscle.J Biol Chem2023
37494443Lysosomal dysfunction in Down syndrome and Alzheimer mouse models is caused by v-ATPase inhibition by Tyr<sup>682</sup>-phosphorylated APP βCTF.Sci Adv2023
37354459PTK7 is a positive allosteric modulator of GPR133 signaling in glioblastoma.Cell Rep2023
37353488Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation.Nat Commun2023
37255534Comparing synaptic proteomes across five mouse models for autism reveals converging molecular similarities including deficits in oxidative phosphorylation and Rho GTPase signaling.Front Aging Neurosci2023
36945411Knockout of cardiolipin synthase disrupts postnatal cardiac development by inhibiting the maturation of mitochondrial cristae.bioRxiv2023
36750096Structures of LRP2 reveal a molecular machine for endocytosis.Cell2023
36691887Cocaine perturbs mitovesicle biology in the brain.J Extracell Vesicles2023
35531097Condensed Mitochondria Assemble Into the Acrosomal Matrix During Spermiogenesis.Front Cell Dev Biol2022
34193971Age-dependent shift in the de novo proteome accompanies pathogenesis in an Alzheimer's disease mouse model.Commun Biol2021
33579698Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in Down syndrome.Sci Adv2021
34824367Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer.Commun Biol2021
34661298Cardiolipin remodeling enables protein crowding in the inner mitochondrial membrane.EMBO J2021
32610141Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone.Cell Rep2020
31959966Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation.Nat Chem Biol2020
31949159The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction.Nat Commun2020
31712250Lipidome-wide <sup>13</sup>C flux analysis: a novel tool to estimate the turnover of lipids in organisms and cultures.J Lipid Res2020
32955430Serine phosphorylation regulates the P-type potassium pump KdpFABC.Elife2020
30914420Extramitochondrial cardiolipin suggests a novel function of mitochondria in spermatogenesis.J Cell Biol2019
31645735A glucose-sensing neuron pair regulates insulin and glucagon in Drosophila.Nature2019
31722197Sam68 Enables Metabotropic Glutamate Receptor-Dependent LTD in Distal Dendritic Regions of CA1 Hippocampal Neurons.Cell Rep2019
30238645Quantitative Comparison of Proteomes Using SILAC.Curr Protoc Protein Sci2019
31388001Haploinsufficiency in the ANKS1B gene encoding AIDA-1 leads to a neurodevelopmental syndrome.Nat Commun2019
31300519PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.J Neurosci2019
29677518Retraction Notice to: ATP Hydrolysis-Dependent Disassembly of the 26S Proteasome Is Part of the Catalytic Cycle.Cell2018
30341316HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons.Nat Commun2018
29392697Sample Preparation for Relative Quantitation of Proteins Using Tandem Mass Tags (TMT) and Mass Spectrometry (MS).Methods Mol Biol2018
28028135Unique Transcriptional Programs Identify Subtypes of AKI.J Am Soc Nephrol2017
32959027Sex-Specific Differences in Oxytocin Receptor Expression and Function for Parental Behavior.Gend Genome2017
29229958EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer.Nat Commun2017
28934508A novel requirement for DROSHA in maintenance of mammalian CG methylation.Nucleic Acids Res2017
28934503A novel requirement for DROSHA in maintenance of mammalian CG methylation.Nucleic Acids Res2017
28619753Inhibition of Hsp90 Suppresses PI3K/AKT/mTOR Signaling and Has Antitumor Activity in Burkitt Lymphoma.Mol Cancer Ther2017
28683321The Ubiquitination of PINK1 Is Restricted to Its Mature 52-kDa Form.Cell Rep2017
27006647N-Terminal Amino Acid Sequence Determination of Proteins by N-Terminal Dimethyl Labeling: Pitfalls and Advantages When Compared with Edman Degradation Sequence Analysis.J Biomol Tech2016
27706135The epichaperome is an integrated chaperome network that facilitates tumour survival.Nature2016
23318451TRIM3, a tumor suppressor linked to regulation of p21(Waf1/Cip1.).Oncogene2014
25026211Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus.Cancer Cell2014
24752897The histone variant MacroH2A1 regulates target gene expression in part by recruiting the transcriptional coregulator PELP1.Mol Cell Biol2014
24934503Affinity purification probes of potential use to investigate the endogenous Hsp70 interactome in cancer.ACS Chem Biol2014
24591208Aminopeptidase activities as prospective urinary biomarkers for bladder cancer.Proteomics Clin Appl2014
23401860Monoubiquitination of filamin B regulates vascular endothelial growth factor-mediated trafficking of histone deacetylase 7.Mol Cell Biol2013
24332853PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex.Cell Rep2013
24036371High-level expression of a full-length Eph receptor.Protein Expr Purif2013
24239008Identification of an allosteric pocket on human hsp70 reveals a mode of inhibition of this therapeutically important protein.Chem Biol2013
23824326USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing.Genes Dev2013
23993092Proteasome-mediated processing of Def1, a critical step in the cellular response to transcription stress.Cell2013
23943653Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies.Blood2013
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Collaborators

Paul Tempst
Memorial Sloan Kettering Cancer Center
Co-authored papers 230
Thomas A Neubert
Neuroscience Institute, NYU Grossman School of Medicine
Co-authored papers 30
Danny Reinberg
HHMI/NYU Langone School of Medicine
Co-authored papers 20
Jesper Q Svejstrup
Panum Institute, University of Copenhagen
Co-authored papers 14
Roger D Kornberg
Stanford University
Co-authored papers 11
C David Allis
The Rockefeller University
Co-authored papers 8
David M Sabatini
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
Co-authored papers 5
Ari Melnick
Co-authored papers 5
Huck-Hui Ng
Co-authored papers 4
Solomon H Snyder
Co-authored papers 4
Siraj M Ali
Foundation Medicine
Co-authored papers 3
Elisa de Stanchina
Co-authored papers 3
Lorenz Studer
The Center for Stem Cell Biology, Memorial Sloan Kettering Cancer Center
Co-authored papers 3
Ze'ev Ronai
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 3
Nikola P Pavletich
Memorial Sloan Kettering Cancer Center
Co-authored papers 3
Robert E W Hancock
University of British Columbia
Co-authored papers 2
Bruce L Kagan
Co-authored papers 2
David Feny??
Institute for Systems Genetics, NYU Grossman School of Medicine
Co-authored papers 2
Stuart H Orkin
Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School
Co-authored papers 2
Harold Varmus
Co-authored papers 2
David D L Bowtell
Peter MacCallum Cancer Centre
Co-authored papers 2
Teit Max Moscote S??gaard
Expres2ion Biotechnologies
Co-authored papers 2
Baggavalli P Somesh
Connexios Life Sciences Pvt Ltd
Co-authored papers 2
Sharmistha Pal
Co-authored papers 2
Robert J Schmitz
University of Georgia
Co-authored papers 2
Judith Frydman
Stanford University
Co-authored papers 2
Kevin Struhl
Co-authored papers 2
Qin Su
Co-authored papers 2
Chris Sander
Broad Institute of MIT and Harvard
Co-authored papers 2
Christoph H Borchers
McGill University
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Release 1.2