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Author Details

John Rush
Cell Signaling Technology Inc.
1987
66
46
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
33710330Correction: RSK phosphorylates SOS1 creating 14-3-3-docking sites and negatively regulating MAPK activation.Biochem J2021
24493012Combinatorial approach for large-scale identification of linked peptides from tandem mass spectrometry spectra.Mol Cell Proteomics2014
25000943Stable-isotope-labeled histone peptide library for histone post-translational modification and variant quantification by mass spectrometry.Mol Cell Proteomics2014
24437954A turn-key approach for large-scale identification of complex posttranslational modifications.J Proteome Res2014
23358503Phosphotyrosine signaling proteins that drive oncogenesis tend to be highly interconnected.Mol Cell Proteomics2013
23749301Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.Nat Methods2013
22345495TSLP signaling network revealed by SILAC-based phosphoproteomics.Mol Cell Proteomics2012
22724890A high-throughput, multiplexed kinase assay using a benchtop orbitrap mass spectrometer to investigate the effect of kinase inhibitors on kinase signaling pathways.Anal Chem2012
22807455Comparative phosphoproteomic analysis of neonatal and adult murine brain.Proteomics2012
22827337RSK phosphorylates SOS1 creating 14-3-3-docking sites and negatively regulating MAPK activation.Biochem J2012
22446692A proteomics approach for the identification and cloning of monoclonal antibodies from serum.Nat Biotechnol2012
22570254Identification of anaplastic lymphoma kinase as a potential therapeutic target in ovarian cancer.Cancer Res2012
22316387Multiplex targeted proteomic assay for biomarker detection in plasma: a pancreatic cancer biomarker case study.J Proteome Res2012
21278249Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease.J Biol Chem2011
21963094Global identification of modular cullin-RING ligase substrates.Cell2011
21906983Systematic and quantitative assessment of the ubiquitin-modified proteome.Mol Cell2011
21552520Survey of activated FLT3 signaling in leukemia.PLoS One2011
21293459Absolute quantification of protein and post-translational modification abundance with stable isotope-labeled synthetic peptides.Nat Protoc2011
21253578Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma.PLoS One2011
19996410Induction of myeloproliferative disorder and myelofibrosis by thrombopoietin receptor W515 mutants is mediated by cytosolic tyrosine 112 of the receptor.Blood2010
21145461Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics.Cell2010
20686178Pathway-based identification of biomarkers for targeted therapeutics: personalized oncology with PI3K pathway inhibitors.Sci Transl Med2010
20736484Akt-RSK-S6 kinase signaling networks activated by oncogenic receptor tyrosine kinases.Sci Signal2010
20506281Fyn promotes phosphorylation of collapsin response mediator protein 1 at tyrosine 504, a novel, isoform-specific regulatory site.J Cell Biochem2010
20377248Gas-phase rearrangements do not affect site localization reliability in phosphoproteomics data sets.J Proteome Res2010
18845790The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL.Blood2009
20038682The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella.J Cell Biol2009
19801977Sensitive multiplexed analysis of kinase activities and activity-based kinase identification.Nat Biotechnol2009
19735572The morphology and biochemistry of nanostructures provide evidence for synthesis and signaling functions in human cerebrospinal fluid.Cerebrospinal Fluid Res2009
19345192Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation.Cell2009
19564600A site-specific, multiplexed kinase activity assay using stable-isotope dilution and high-resolution mass spectrometry.Proc Natl Acad Sci U S A2009
19105742Mass spectrometry based targeted protein quantification: methods and applications.J Proteome Res2009
19156127Linear combinations of docking affinities explain quantitative differences in RTK signaling.Mol Syst Biol2009
18180459Signaling networks assembled by oncogenic EGFR and c-Met.Proc Natl Acad Sci U S A2008
18721752System-wide investigation of ErbB4 reveals 19 sites of Tyr phosphorylation that are unusually selective in their recruitment properties.Chem Biol2008
18493663A quantitative study of the recruitment potential of all intracellular tyrosine residues on EGFR, FGFR1 and IGF1R.Mol Biosyst2008
18186601Application of targeted quantitative proteomics analysis in human cerebrospinal fluid using a liquid chromatography matrix-assisted laser desorption/ionization time-of-flight tandem mass spectrometer (LC MALDI TOF/TOF) platform.J Proteome Res2008
17484111The absolute quantification strategy: application to phosphorylation profiling of human separase serine 1126.Methods Mol Biol2007
18083107Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.Cell2007
18077418Profiling of UV-induced ATM/ATR signaling pathways.Proc Natl Acad Sci U S A2007
17360941A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia.Blood2007
17252008Phosphoproteomic analysis identifies the M0-91 cell line as a cellular model for the study of TEL-TRKC fusion-associated leukemia.Leukemia2007
16204703Phosphorylation analysis by mass spectrometry: myths, facts, and the consequences for qualitative and quantitative measurements.Mol Cell Proteomics2006
16799550Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology.Nat Cell Biol2006
16964243A probability-based approach for high-throughput protein phosphorylation analysis and site localization.Nat Biotechnol2006
16946300Phosphotyrosine profiling identifies the KG-1 cell line as a model for the study of FGFR1 fusions in acute myeloid leukemia.Blood2006
16507876Relative and absolute quantification of postsynaptic density proteome isolated from rat forebrain and cerebellum.Mol Cell Proteomics2006
16497976A common phosphotyrosine signature for the Bcr-Abl kinase.Blood2006
15592455Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.Nat Biotechnol2005
15951569Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.Mol Cell Proteomics2005
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Collaborators

Harvard Medical School
Co-authored papers 15
Co-authored papers 13
University of Washington
Co-authored papers 8
College of Animal Medicine, Xinjiang Agricultural University
Co-authored papers 7
Seattle Children's Research Institute, University of Washington
Co-authored papers 4
Oregon Health & Science University
Co-authored papers 3
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 2
Oregon Health & Science University School of Medicine
Co-authored papers 2
Co-authored papers 2
University of Virginia
Co-authored papers 2
IRIC - University of Montreal
Co-authored papers 2
University of Victoria
Co-authored papers 2
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
University of California
Co-authored papers 2
Institute for Research in Immunology and Cancer (IRIC)
Co-authored papers 2
University of Washington
Co-authored papers 2
Harvard Medical School
Co-authored papers 2
Harvard Medical School
Co-authored papers 1
VILLUM Center for Bioanalytical Sciences, University of Southern Denmark
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine
Co-authored papers 1
Harvard Medical School
Co-authored papers 1
Penn Epigenetics Institute, Perelman School of Medicine
Co-authored papers 1
Co-authored papers 1
Stanford University
Co-authored papers 1
Massachusetts Institute of Technology
Co-authored papers 1
University of Washington
Co-authored papers 1
University of Pennsylvania
Co-authored papers 1