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Author Details
Full Name
Andreas Gnirke
Affiliation
The Center for Genome Architecture, Baylor College of Medicine
ORCID
Career Start Year
1986
Papers
113
H Index
71
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
37327786
DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs.
Cell
2023
38032990
A rapid, low-cost, and highly sensitive SARS-CoV-2 diagnostic based on whole-genome sequencing.
PLoS One
2023
37289095
Genome Sequence of Lichtheimia ornata, an Emerging Opportunistic Mucorales Pathogen.
Microbiol Resour Announc
2023
33303686
Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events.
Science
2021
33604581
Preneoplastic Alterations Define CLL DNA Methylome and Persist through Disease Progression and Therapy.
Blood Cancer Discov
2021
34686499
Activation of <i>Notch</i> and <i>Myc</i> Signaling via B-cell-Restricted Depletion of <i>Dnmt3a</i> Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia.
Cancer Res
2021
34244697
Smart-RRBS for single-cell methylome and transcriptome analysis.
Nat Protoc
2021
33972312
Discovery of Candidate DNA Methylation Cancer Driver Genes.
Cancer Discov
2021
32514123
TETs compete with DNMT3 activity in pluripotent cells at thousands of methylated somatic enhancers.
Nat Genet
2020
32938797
Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect.
Sci Transl Med
2020
32869040
Phylogenetic analysis of SARS-CoV-2 in the Boston area highlights the role of recurrent importation and superspreading events.
medRxiv
2020
30718881
Capturing sequence diversity in metagenomes with comprehensive and scalable probe design.
Nat Biotechnol
2019
31348885
Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy.
Cell
2019
31015400
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL.
Nat Commun
2019
31092926
Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia.
Nature
2019
29426832
Genome-wide tracking of dCas9-methyltransferase footprints.
Nat Commun
2018
30337375
Comparative genomic analysis of embryonic, lineage-converted and stem cell-derived motor neurons.
Development
2018
30468428
Targets and genomic constraints of ectopic Dnmt3b expression.
Elife
2018
29581568
Author Correction: Global delay in nascent strand DNA methylation.
Nat Struct Mol Biol
2018
29551301
Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology.
Cell Stem Cell
2018
29358654
Genetic determinants and epigenetic effects of pioneer-factor occupancy.
Nat Genet
2018
29656892
Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade.
Cell
2018
29531288
Global delay in nascent strand DNA methylation.
Nat Struct Mol Biol
2018
28746311
Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells.
Nature
2017
28405027
Virus genomes reveal factors that spread and sustained the Ebola epidemic.
Nature
2017
28959968
Epigenetic restriction of extraembryonic lineages mirrors the somatic transition to cancer.
Nature
2017
28538734
Zika virus evolution and spread in the Americas.
Nature
2017
28538723
Genomic epidemiology reveals multiple introductions of Zika virus into the United States.
Nature
2017
25794114
Patient satisfaction in out-of-hospital emergency care: a multicentre survey.
Eur J Emerg Med
2016
27980681
Targeted bisulfite sequencing of the dynamic DNA methylome.
Epigenetics Chromatin
2016
27157321
Development and Validation of a Mass Spectrometry-Based Assay for the Molecular Diagnosis of Mucin-1 Kidney Disease.
J Mol Diagn
2016
25533951
Dissecting neural differentiation regulatory networks through epigenetic footprinting.
Nature
2015
26276630
Clinical Sequencing Uncovers Origins and Evolution of Lassa Virus.
Cell
2015
26499245
Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes.
Proc Natl Acad Sci U S A
2015
26091036
Ebola Virus Epidemiology, Transmission, and Evolution during Seven Months in Sierra Leone.
Cell
2015
25693565
Transcription factor binding dynamics during human ES cell differentiation.
Nature
2015
25730492
Simultaneous generation of many RNA-seq libraries in a single reaction.
Nat Methods
2015
25822089
Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells.
Nat Genet
2015
25742749
Notch-mediated expansion of cord blood progenitors: maintenance of transcriptional and epigenetic fidelity.
Leukemia
2015
24914046
Comprehensive mutational scanning of a kinase in vivo reveals substrate-dependent fitness landscapes.
Nucleic Acids Res
2014
25490447
Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia.
Cancer Cell
2014
25214632
Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak.
Science
2014
25403361
Enhanced methods for unbiased deep sequencing of Lassa and Ebola RNA viruses from clinical and biological samples.
Genome Biol
2014
23396133
Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing.
Nat Genet
2013
23925113
Charting a dynamic DNA methylation landscape of the human genome.
Nature
2013
23664763
Transcriptional and epigenetic dynamics during specification of human embryonic stem cells.
Cell
2013
23685885
Comparative analysis of RNA sequencing methods for degraded or low-input samples.
Nat Methods
2013
23685454
Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells.
Nature
2013
23598338
The African coelacanth genome provides insights into tetrapod evolution.
Nature
2013
23791531
Cellular source and mechanisms of high transcriptome complexity in the mammalian testis.
Cell Rep
2013
1 - 50 of 113
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