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Author Details

Andreas Gnirke
The Center for Genome Architecture, Baylor College of Medicine
1986
113
71
PMIDPaper TitleJournal TitlePublished Year
37327786DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs.Cell2023
38032990A rapid, low-cost, and highly sensitive SARS-CoV-2 diagnostic based on whole-genome sequencing.PLoS One2023
37289095Genome Sequence of Lichtheimia ornata, an Emerging Opportunistic Mucorales Pathogen.Microbiol Resour Announc2023
33303686Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events.Science2021
33604581Preneoplastic Alterations Define CLL DNA Methylome and Persist through Disease Progression and Therapy.Blood Cancer Discov2021
34686499Activation of <i>Notch</i> and <i>Myc</i> Signaling via B-cell-Restricted Depletion of <i>Dnmt3a</i> Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia.Cancer Res2021
34244697Smart-RRBS for single-cell methylome and transcriptome analysis.Nat Protoc2021
33972312Discovery of Candidate DNA Methylation Cancer Driver Genes.Cancer Discov2021
32514123TETs compete with DNMT3 activity in pluripotent cells at thousands of methylated somatic enhancers.Nat Genet2020
32938797Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect.Sci Transl Med2020
32869040Phylogenetic analysis of SARS-CoV-2 in the Boston area highlights the role of recurrent importation and superspreading events.medRxiv2020
30718881Capturing sequence diversity in metagenomes with comprehensive and scalable probe design.Nat Biotechnol2019
31348885Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy.Cell2019
31015400Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL.Nat Commun2019
31092926Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia.Nature2019
29426832Genome-wide tracking of dCas9-methyltransferase footprints.Nat Commun2018
30337375Comparative genomic analysis of embryonic, lineage-converted and stem cell-derived motor neurons.Development2018
30468428Targets and genomic constraints of ectopic Dnmt3b expression.Elife2018
29581568Author Correction: Global delay in nascent strand DNA methylation.Nat Struct Mol Biol2018
29551301Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology.Cell Stem Cell2018
29358654Genetic determinants and epigenetic effects of pioneer-factor occupancy.Nat Genet2018
29656892Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade.Cell2018
29531288Global delay in nascent strand DNA methylation.Nat Struct Mol Biol2018
28746311Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells.Nature2017
28405027Virus genomes reveal factors that spread and sustained the Ebola epidemic.Nature2017
28959968Epigenetic restriction of extraembryonic lineages mirrors the somatic transition to cancer.Nature2017
28538734Zika virus evolution and spread in the Americas.Nature2017
28538723Genomic epidemiology reveals multiple introductions of Zika virus into the United States.Nature2017
25794114Patient satisfaction in out-of-hospital emergency care: a multicentre survey.Eur J Emerg Med2016
27980681Targeted bisulfite sequencing of the dynamic DNA methylome.Epigenetics Chromatin2016
27157321Development and Validation of a Mass Spectrometry-Based Assay for the Molecular Diagnosis of Mucin-1 Kidney Disease.J Mol Diagn2016
25533951Dissecting neural differentiation regulatory networks through epigenetic footprinting.Nature2015
26276630Clinical Sequencing Uncovers Origins and Evolution of Lassa Virus.Cell2015
26499245Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes.Proc Natl Acad Sci U S A2015
26091036Ebola Virus Epidemiology, Transmission, and Evolution during Seven Months in Sierra Leone.Cell2015
25693565Transcription factor binding dynamics during human ES cell differentiation.Nature2015
25730492Simultaneous generation of many RNA-seq libraries in a single reaction.Nat Methods2015
25822089Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells.Nat Genet2015
25742749Notch-mediated expansion of cord blood progenitors: maintenance of transcriptional and epigenetic fidelity.Leukemia2015
24914046Comprehensive mutational scanning of a kinase in vivo reveals substrate-dependent fitness landscapes.Nucleic Acids Res2014
25490447Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia.Cancer Cell2014
25214632Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak.Science2014
25403361Enhanced methods for unbiased deep sequencing of Lassa and Ebola RNA viruses from clinical and biological samples.Genome Biol2014
23396133Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing.Nat Genet2013
23925113Charting a dynamic DNA methylation landscape of the human genome.Nature2013
23664763Transcriptional and epigenetic dynamics during specification of human embryonic stem cells.Cell2013
23685885Comparative analysis of RNA sequencing methods for degraded or low-input samples.Nat Methods2013
23685454Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells.Nature2013
23598338The African coelacanth genome provides insights into tetrapod evolution.Nature2013
23791531Cellular source and mechanisms of high transcriptome complexity in the mammalian testis.Cell Rep2013
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