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Author Details

Lucy Thorne
University College London
1992
36
19
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36693093SARS-CoV-2 evolution influences GBP and IFITM sensitivity.Proc Natl Acad Sci U S A2023
36653446SARS-CoV-2 variant biology: immune escape, transmission and fitness.Nat Rev Microbiol2023
35332335Publisher Correction: Evolution of enhanced innate immune evasion by SARS-CoV-2.Nature2022
35999696Evolutionary remodelling of N-terminal domain loops fine-tunes SARS-CoV-2 spike.EMBO Rep2022
35012962Preclinical and randomized phase I studies of plitidepsin in adults hospitalized with COVID-19.Life Sci Alliance2022
34942634Evolution of enhanced innate immune evasion by SARS-CoV-2.Nature2022
34101213SARS-CoV-2 sensing by RIG-I and MDA5 links epithelial infection to macrophage inflammation.EMBO J2021
33791702Characterisation of B.1.1.7 and Pangolin coronavirus spike provides insights on the evolutionary trajectory of SARS-CoV-2.bioRxiv2021
34491891Murine norovirus virulence factor 1 (VF1) protein contributes to viral fitness during persistent infection.J Gen Virol2021
34075384Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization.medRxiv2021
34127972Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant.bioRxiv2021
33300875HIV-1 Vpr antagonizes innate immune activation by targeting karyopherin-mediated NF-κB/IRF3 nuclear transport.Elife2020
29683421Targeting macrophage- and intestinal epithelial cell-specific microRNAs against norovirus restricts replication in vivo.J Gen Virol2018
29912471The First Norovirus Longitudinal Seroepidemiological Study From Sub-Saharan Africa Reveals High Seroprevalence of Diverse Genotypes Associated With Host Susceptibility Factors.J Infect Dis2018
29900416miR-155 induction is a marker of murine norovirus infection but does not contribute to control of replication <i>in vivo</i>.Wellcome Open Res2018
30416070Cyclosporine H Overcomes Innate Immune Restrictions to Improve Lentiviral Transduction and Gene Editing In Human Hematopoietic Stem Cells.Cell Stem Cell2018
28771521Regulation of type 1 diabetes development and B-cell activation in nonobese diabetic mice by early life exposure to a diabetogenic environment.PLoS One2017
28362906Reply to Kempf et al.J Infect Dis2017
28405027Virus genomes reveal factors that spread and sustained the Ebola epidemic.Nature2017
29056936Are Evolution and the Intracellular Innate Immune System Key Determinants in HIV Transmission?Front Immunol2017
28698274Noroviruses Co-opt the Function of Host Proteins VAPA and VAPB for Replication via a Phenylalanine-Phenylalanine-Acidic-Tract-Motif Mimic in Nonstructural Viral Protein NS1/2.mBio2017
26744429Advances Toward a Norovirus Antiviral: From Classical Inhibitors to Lethal Mutagenesis.J Infect Dis2016
28694998Rapid outbreak sequencing of Ebola virus in Sierra Leone identifies transmission chains linked to sporadic cases.Virus Evol2016
27777985Norovirus Polymerase Fidelity Contributes to Viral Transmission <i>In Vivo</i>.mSphere2016
27093560Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial.PLoS Med2016
25392209The murine norovirus core subgenomic RNA promoter consists of a stable stem-loop that can direct accurate initiation of RNA synthesis.J Virol2015
26539753Genotypic anomaly in Ebola virus strains circulating in Magazine Wharf area, Freetown, Sierra Leone, 2015.Euro Surveill2015
25520198Subgenomic promoter recognition by the norovirus RNA-dependent RNA polymerases.Nucleic Acids Res2015
24243731Norovirus gene expression and replication.J Gen Virol2014
25333492Favipiravir elicits antiviral mutagenesis during virus replication in vivo.Elife2014
24789596Murine norovirus: propagation, quantification, and genetic manipulation.Curr Protoc Microbiol2014
22395237Identification of protein interacting partners using tandem affinity purification.J Vis Exp2012
22760450Reverse genetics mediated recovery of infectious murine norovirus.J Vis Exp2012
22915807High-resolution functional profiling of the norovirus genome.J Virol2012
20130064Interleukin 18 coexpression during respiratory syncytial virus infection results in enhanced disease mediated by natural killer cells.J Virol2010
1487029Cell spreading on collagen that has been exposed to reactive aldehydes.Biochem Soc Trans1992
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Collaborators

Ian Goodfellow
University of Cambridge
Co-authored papers 24
Greg J Towers
University College London
Co-authored papers 13
Clare Jolly
University College London
Co-authored papers 9
Ann-Kathrin Reuschl
University College London
Co-authored papers 9
Lorena Zuliani-Alvarez
J. David Gladstone Institutes
Co-authored papers 7
Mahdad Noursadeghi
University College London
Co-authored papers 5
Mehdi Bouhaddou
J. David Gladstone Institutes
Co-authored papers 5
Adolfo Garc??a-Sastre
Icahn School of Medicine at Mount Sinai
Co-authored papers 5
Kirsten Obernier (CM4AI)
University of California San Francisco
Co-authored papers 5
Matthew V X Whelan
University College London
Co-authored papers 5
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 5
Myra Hosmillo
University of Cambridge
Co-authored papers 4
Aminu S Jahun
University of Cambridge, Addenbrooke's Hospital Level 5
Co-authored papers 4
Romel Rosales
Icahn School of Medicine at Mount Sinai
Co-authored papers 4
Kris M White
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 4
Jane Turner
University College London
Co-authored papers 4
Danish Memon
European Bioinformatics Institute
Co-authored papers 3
Pedro Beltrao
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 3
Manisha Ummadi
University of California, San Francisco
Co-authored papers 3
Natalia Jura
Cardiovascular Research Institute, University of California San Francisco
Co-authored papers 3
Danielle L Swaney
J. David Gladstone Institutes
Co-authored papers 3
Joseph B Hiatt
Fred Hutchinson Cancer Center
Co-authored papers 3
Adrian Pelin
University of Ottawa
Co-authored papers 3
Margaret Soucheray
J. David Gladstone Institutes
Co-authored papers 3
Kliment A Verba
University of California, University of California San Francisco
Co-authored papers 3
Paola Bonfanti
University College London
Co-authored papers 3
Jyoti Batra
J. David Gladstone Institutes
Co-authored papers 3
Alicia L Richards
University of Wisconsin-Madison
Co-authored papers 3
Kevan M Shokat
University of California San Francisco
Co-authored papers 3
Hannes Braberg
University of California San Francisco
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Release 1.2