Author details

Full Name

Bo Wen

Affiliation

ORCID

Career Start Year

2004

Papers

257

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37523716	Discovery of SMD-3040 as a Potent and Selective SMARCA2 PROTAC Degrader with Strong Antitumor Activity.		2023
36370930	A steamed broccoli sprout diet preparation that reduces colitis via the gut microbiota.	Journal of Nutritional Biochemistry	2023
36156361	Maternal plasma diacylglycerols and triacylglycerols in the prediction of gestational diabetes mellitus.	BJOG: An International Journal of Obstetrics and Gynaecology	2023
37647546	Discovery of as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader with Strong Antitumor Activity.		2023
37705593	Prophylactic Mitigation of Acute Graft versus Host Disease by Novel 2-(Pyrrolidin-1-ylmethyl)pyrrole-Based Stimulation-2 (ST2) Inhibitors.	ACS Pharmacol Transl Sci	2023
37683104	Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR + Human Prostate Cancer.	J Med Chem	2023
36711982	Deep learning prediction boosts phosphoproteomics-based discoveries through improved phosphopeptide identification.	bioRxiv	2023
37276143	Discovery of Exceptionally Potent, Selective, and Efficacious PROTAC Degraders of CBP and p300 Proteins.		2023
37072382	PepQuery2 democratizes public MS proteomics data for rapid peptide searching.	Nat Commun	2023
37382562	Discovery of ARD-2051 as a Potent and Orally Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer.		2023
37314445	Prolonging the therapeutic window for valproic acid treatment in a swine model of traumatic brain injury and hemorrhagic shock.		2023
37059606	Corrigendum to "A steamed broccoli sprout diet preparation that reduces colitis via the gut microbiota" [J Nutr Biochem 2023;112:109215].		2023
36735833	Discovery of a Potent and Selective STAT5 PROTAC Degrader with Strong Antitumor Activity in Acute Myeloid Leukemia.		2023
36732620	A selective small-molecule STAT5 PROTAC degrader capable of achieving tumor regression in vivo.		2023
37040763	DT-109 ameliorates nonalcoholic steatohepatitis in nonhuman primates.		2023
34931020	Using noninvasive adjusted pulse transit time for tracking beat-to-beat systolic blood pressure during ventricular arrhythmia.	Hypertension Research	2022
35646532	Structureâ¿¿tissue exposure/selectivity relationship (STR) correlates with clinical efficacy/safety.	Acta Pharmaceutica Sinica B	2022
36342141	Effects of Fluticasone Propionate on <i>Klebsiella pneumoniae</i> and Gram-Negative Bacteria Associated with Chronic Airway Disease.	mSphere	2022
36341345	Molecular profiling of core immune-escape genes highlights LCK as an immune-related prognostic biomarker in melanoma.	Frontiers in Immunology	2022
36001024	Proteogenomic Markers of Chemotherapy Resistance and Response in Triple-Negative Breast Cancer.	Cancer Discov	2022
36271853	OmicsEV: a tool for comprehensive quality evaluation of omics data tables.	Bioinformatics	2022
36208082	Application of a new volumetric microsampling device for quantitative bioanalysis of immunosuppression.	Bioanalysis	2022
36070561	Optimization of the Prodrug Moiety of Remdesivir to Improve Lung Exposure/Selectivity and Enhance Anti-SARS-CoV-2 Activity.	Journal of Medicinal Chemistry	2022
35930851	Structure-Activity relationship of 1-(Furan-2ylmethyl)Pyrrolidine-Based Stimulation-2 (ST2) inhibitors for treating graft versus host disease.	Bioorg Med Chem	2022
36644425	Pestle Needle () Treatment for Neck Pain.		2022
34755346	The performance of water-soluble fluoride transformation in soil-tea-tea infusion chain system and the potential health risk assessment.	Journal of the Science of Food and Agriculture	2022
34473519	Discovery of ARD-2585 as an Exceptionally Potent and Orally Active PROTAC Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer.	Journal of Medicinal Chemistry	2021
34288417	Advances in Understanding the Electrocatalytic Reconstruction Chemistry of Coordination Compounds.	Small	2021
33682631	Comparative pharmacokinetic analysis of the blood-brain barrier penetration of dasatinib and ponatinib in mice.	Leuk Lymphoma	2021
34050565	Comprehensive Understandings into Complete Reconstruction of Precatalysts: Synthesis, Applications, and Characterizations.	Advanced Materials	2021
33887487	Feature Selection Methods for Protein Biomarker Discovery from Proteomics or Multiomics Data.	Mol Cell Proteomics	2021
33990599	Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity.	Nature Communications	2021
34144373	Reappraisal of anticancer nanomedicine design criteria in three types of preclinical cancer models for better clinical translation.	Biomaterials	2021
34141084	SD-91 as A Potent and Selective STAT3 Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression.	ACS Medicinal Chemistry Letters	2021
34036290	A community effort to identify and correct mislabeled samples in proteogenomic studies.	Patterns (N Y)	2021
34252297	Pharmacokinetics of Polymyxin B in Hospitalized Adults with Cystic Fibrosis.	Antimicrobial Agents and Chemotherapy	2021
34320345	Dysregulated oxalate metabolism is a driver and therapeutic target in atherosclerosis.	Cell Reports	2021
33341649	Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy.	European Journal of Medicinal Chemistry	2021
33417831	Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma.	Cancer Cell	2021
34737085	Deep-Learning-Derived Evaluation Metrics Enable Effective Benchmarking of Computational Tools for Phosphopeptide Identification.	Mol Cell Proteomics	2021
34622160	caAtlas: An immunopeptidome atlas of human cancer.	iScience	2021
34613724	Discovery of EEDi-5273 as an Exceptionally Potent and Orally Efficacious EED Inhibitor Capable of Achieving Complete and Persistent Tumor Regression.	Journal of Medicinal Chemistry	2021
34603031	Andrographolide Sulfonate Is a Promising Treatment to Combat Methicillin-resistant and Its Biofilms.	Frontiers in Pharmacology	2021
34431670	Strategies toward Discovery of Potent and Orally Bioavailable Proteolysis Targeting Chimera Degraders of Androgen Receptor for the Treatment of Prostate Cancer.	Journal of Medicinal Chemistry	2021
34879325	Phospholipid nanoparticles: Therapeutic potentials against atherosclerosis via reducing cholesterol crystals and inhibiting inflammation.	eBioMedicine	2021
30892255	Multi-Sensor Fusion Approach for Cuff-Less Blood Pressure Measurement.	IEEE Journal of Biomedical and Health Informatics	2020
36659144	Facile formation of tetragonal-NbO microspheres for high-rate and stable lithium storage with high areal capacity.		2020
32327351	Synthesis and structure-activity relationships of thieno[2,3-d]pyrimidines as atypical protein kinase C inhibitors to control retinal vascular permeability and cytokine-induced edema.	Bioorganic and Medicinal Chemistry	2020
32027110	Discovery and Optimization of Triazine Nitrile Inhibitors of Cathepsin L for the Potential Treatment of Chronic Toxoplasmosis in the CNS.	ACS Chemical Neuroscience	2020
31855575	Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia.	Journal of Clinical Investigation	2020