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Author Details

Ranjini K Sundaram
Yale University
1996
32
18
PMIDPaper TitleJournal TitlePublished Year
35273342In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2.Leukemia2022
35439320TOP1-DNA Trapping by Exatecan and Combination Therapy with ATR Inhibitor.Mol Cancer Ther2022
35388070Mismatch repair proteins play a role in ATR activation upon temozolomide treatment in MGMT-methylated glioblastoma.Sci Rep2022
35901163Mechanism-based design of agents that selectively target drug-resistant glioma.Science2022
36128328Targeting Krebs-cycle-deficient renal cell carcinoma with Poly ADP-ribose polymerase inhibitors and low-dose alkylating chemotherapy.Oncotarget2022
34027408Targeting IDH1/2 mutant cancers with combinations of ATR and PARP inhibitors.NAR Cancer2021
34888524Correction to 'Tumor-selective, antigen-independent delivery of a pH sensitive peptide-topoisomerase inhibitor conjugate suppresses tumor growth without systemic toxicity'.NAR Cancer2021
34316708Tumor-selective, antigen-independent delivery of a pH sensitive peptide-topoisomerase inhibitor conjugate suppresses tumor growth without systemic toxicity.NAR Cancer2021
34118569Loss of ATRX confers DNA repair defects and PARP inhibitor sensitivity.Transl Oncol2021
33953843Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore.Oncotarget2021
31439867PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma.Nat Commun2019
31273061Temozolomide Sensitizes MGMT-Deficient Tumor Cells to ATR Inhibitors.Cancer Res2019
30013182Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination DNA repair.Nat Genet2018
29936153Biodegradable PEG-poly(Ï¿-pentadecalactone-co-p-dioxanone) nanoparticles for enhanced and sustained drug delivery to treat brain tumors.Biomaterials2018
28566437Local DNA Repair Inhibition for Sustained Radiosensitization of High-Grade Gliomas.Mol Cancer Ther2017
281488392-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity.Sci Transl Med2017
28834754SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination.Cell Rep2017
26927829Characterization of Cardiac Glycoside Natural Products as Potent Inhibitors of DNA Double-Strand Break Repair by a Whole-Cell Double Immunofluorescence Assay.J Am Chem Soc2016
25547252Development of a novel method to create double-strand break repair fingerprints using next-generation sequencing.DNA Repair (Amst)2015
26468228Prospective analysis of antigen-specific immunity, stem-cell antigens, and immune checkpoints in monoclonal gammopathy.Blood2015
25512618Identification of novel radiosensitizers in a high-throughput, cell-based screen for DSB repair inhibitors.Mol Cancer Ther2015
25244580Patents on potential drugs to treat Alzheimer's disease: special emphasis on small peptides.Recent Pat CNS Drug Discov2014
23100308Clinical regressions and broad immune activation following combination therapy targeting human NKT cells in myeloma.Blood2013
22234692Dendritic cell-mediated activation-induced cytidine deaminase (AID)-dependent induction of genomic instability in human myeloma.Blood2012
22712003Novel Detox Gel Depot sequesters β-Amyloid Peptides in a mouse model of Alzheimer's Disease.Int J Pept Res Ther2012
22585510Protein stains and applications.Methods Mol Biol2012
18331732Genetic transformation of a Corynebacterial symbiont from the Chagas disease vector Triatoma infestans.Exp Parasitol2008
18322717Expression of a functional single-chain antibody via Corynebacterium pseudodiphtheriticum.Eur J Clin Microbiol Infect Dis2008
18288928Detoxification depot for beta-amyloid peptides.Curr Alzheimer Res2008
12097575Ubiquitin-fused and/or multiple early genes from cottontail rabbit papillomavirus as DNA vaccines.J Virol2002
10456459Role of tissue factor in metastasis: functions of the cytoplasmic and extracellular domains of the molecule.Thromb Haemost1999
8777831Antioxidant status and lipid peroxidation in type II diabetes mellitus with and without complications.Clin Sci (Lond)1996
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Collaborators

Yale University School of Medicine
Co-authored papers 20
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Co-authored papers 3
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Wayne State University School of Medicine, Barbara Ann Karmanos Cancer Institute
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University of California los angeles
Co-authored papers 2
Institute of Urologic Oncology, University of California Los Angeles
Co-authored papers 2
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Yale University School of Medicine
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Yale University
Co-authored papers 1
Stomatology Hospital, Zhejiang University School of Medicine
Co-authored papers 1
institute of urology
Co-authored papers 1
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
Co-authored papers 1
Yale School of Medicine
Co-authored papers 1
University of California los angeles
Co-authored papers 1
Co-authored papers 1
USA University of Zurich
Co-authored papers 1
Yale University School of Medicine
Co-authored papers 1
Co-authored papers 1
Karmanos Cancer Institute, Wayne State University
Co-authored papers 1
University of California los angeles
Co-authored papers 1
College of Optical Science and Engineering, Zhejiang University
Co-authored papers 1
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Yale School of Medicine
Co-authored papers 1