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Author Details

Linda T Vahdat
Dartmouth Cancer Center
1993
152
55
PMIDPaper TitleJournal TitlePublished Year
37583435Cancer Epidemiology in the Northeastern United States (2013-2017).Cancer Res Commun2023
37480151Copper chelation suppresses epithelial-mesenchymal transition by inhibition of canonical and non-canonical TGF-β signaling pathways in cancer.Cell Biosci2023
34764459Connecting copper and cancer: from transition metal signalling to metalloplasia.Nat Rev Cancer2022
35896617Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer.Oncogene2022
34116144Biomarker analyses in the phase III ASCENT study of sacituzumab govitecan versus chemotherapy in patients with metastatic triple-negative breast cancer.Ann Oncol2021
33741442Sacituzumab govitecan, a Trop-2-directed antibody-drug conjugate, for patients with epithelial cancer: final safety and efficacy results from the phase I/II IMMU-132-01 basket trial.Ann Oncol2021
34944703Evaluation of ATOX1 as a Potential Predictive Biomarker for Tetrathiomolybdate Treatment of Breast Cancer Patients with High Risk of Recurrence.Biomedicines2021
34911956Copper depletion modulates mitochondrial oxidative phosphorylation to impair triple negative breast cancer metastasis.Nat Commun2021
34426581Tetrathiomolybdate (TM)-associated copper depletion influences collagen remodeling and immune response in the pre-metastatic niche of breast cancer.NPJ Breast Cancer2021
34016993Glembatumumab vedotin for patients with metastatic, gpNMB overexpressing, triple-negative breast cancer ("METRIC"): a randomized multicenter study.NPJ Breast Cancer2021
32613539Dermatologic adverse events related to the PI3Kα inhibitor alpelisib (BYL719) in patients with breast cancer.Breast Cancer Res Treat2020
31968251Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer.Cell Rep2020
32946924Sacituzumab govitecan in previously treated hormone receptor-positive/HER2-negative metastatic breast cancer: final results from a phase I/II, single-arm, basket trial.Ann Oncol2020
32934032Correction: Influencing the Tumor Microenvironment: A Phase II Study of Copper Depletion Using Tetrathiomolybdate in Patients with Breast Cancer at High Risk for Recurrence and in Preclinical Models of Lung Metastases.Clin Cancer Res2020
30511901Personalized Nutrition in Disrupting Cancer - Proceedings From the 2017 American College of Nutrition Annual Meeting.J Am Coll Nutr2019
31195996Health-related quality of life in patients receiving first-line eribulin mesylate with or without trastuzumab for locally recurrent or metastatic breast cancer.BMC Cancer2019
31592503Integrative Molecular Analysis of Patients With Advanced and Metastatic Cancer.JCO Precis Oncol2019
31089928Clinical benefit, toxicity and cost of metastatic breast cancer therapies: systematic review and meta-analysis.Breast Cancer Res Treat2019
30855113Copper Depletion as a Therapeutic Strategy in Cancer.Met Ions Life Sci2019
30999962Regular use of aspirin and other non-steroidal anti-inflammatory drugs and breast cancer risk for women at familial or genetic risk: a cohort study.Breast Cancer Res2019
30786188Sacituzumab Govitecan-hziy in Refractory Metastatic Triple-Negative Breast Cancer.N Engl J Med2019
29706375Balixafortide plus eribulin in HER2-negative metastatic breast cancer: a phase 1, single-arm, dose-escalation trial.Lancet Oncol2018
30240327Multicenter Phase II Study of Lurbinectedin in BRCA-Mutated and Unselected Metastatic Advanced Breast Cancer and Biomarker Assessment Substudy.J Clin Oncol2018
30153978Efficacy and Safety of Ixabepilone and Capecitabine in Patients With Advanced Triple-negative Breast Cancer: a Pooled Analysis From Two Large Phase III, Randomized Clinical Trials.Clin Breast Cancer2018
30007894A phase IIA trial of acupuncture to reduce chemotherapy-induced peripheral neuropathy severity during neoadjuvant or adjuvant weekly paclitaxel chemotherapy in breast cancer patients.Eur J Cancer2018
30505260Functional Peptide Nanofibers with Unique Tumor Targeting and Enzyme-Induced Local Retention Properties.Adv Funct Mater2018
27830395Glutamine for the treatment of vincristine-induced neuropathy in children and adolescents with cancer.Support Care Cancer2017
28356425Efficacy of the PARP Inhibitor Veliparib with Carboplatin or as a Single Agent in Patients with Germline <i>BRCA1</i>- or <i>BRCA2</i>-Associated Metastatic Breast Cancer: California Cancer Consortium Trial NCT01149083.Clin Cancer Res2017
28220020Randomized Phase II Study of Ramucirumab or Icrucumab in Combination with Capecitabine in Patients with Previously Treated Locally Advanced or Metastatic Breast Cancer.Oncologist2017
28291390Efficacy and Safety of Anti-Trop-2 Antibody Drug Conjugate Sacituzumab Govitecan (IMMU-132) in Heavily Pretreated Patients With Metastatic Triple-Negative Breast Cancer.J Clin Oncol2017
28945887Hybrid capture-based genomic profiling of circulating tumor DNA from patients with estrogen receptor-positive metastatic breast cancer.Ann Oncol2017
28813674An Integrated Systems Biology Approach Identifies TRIM25 as a Key Determinant of Breast Cancer Metastasis.Cell Rep2017
28558150Sacituzumab govitecan (IMMU-132), an anti-Trop-2-SN-38 antibody-drug conjugate for the treatment of diverse epithelial cancers: Safety and pharmacokinetics.Cancer2017
28503956Sacituzumab govitecan: an antibody-drug conjugate.Expert Opin Biol Ther2017
27769988Influencing the Tumor Microenvironment: A Phase II Study of Copper Depletion Using Tetrathiomolybdate in Patients with Breast Cancer at High Risk for Recurrence and in Preclinical Models of Lung Metastases.Clin Cancer Res2017
26719537Activation of Hematopoietic Stem/Progenitor Cells Promotes Immunosuppression Within the Pre-metastatic Niche.Cancer Res2016
30190890Copper suppression as cancer therapy: the rationale for copper chelating agents in <i>BRAF</i><sup>V600</sup> mutated melanoma.Melanoma Manag2016
27994483Clinical effects of prior trastuzumab on combination eribulin mesylate plus trastuzumab as first-line treatment for human epidermal growth factor receptor 2 positive locally recurrent or metastatic breast cancer: results from a Phase II, single-arm, multicenter study.Breast Cancer (Dove Med Press)2016
27180972Smart Nanotransformers with Unique Enzyme-Inducible Structural Changes and Drug Release Properties.Biomacromolecules2016
25573650Erratum to: Efficacy of eribulin in women with metastatic breast cancer: a pooled analysis of two phase 3 studies.Breast Cancer Res Treat2015
26413438Impact of prior anthracycline or taxane use on eribulin effectiveness as first-line treatment for metastatic breast cancer: results from two phase 2, multicenter, single-arm studies.Springerplus2015
26560033Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance.Nature2015
26290412Obesity-dependent changes in interstitial ECM mechanics promote breast tumorigenesis.Sci Transl Med2015
25885598Pro1170 Ala polymorphism in HER2-neu is associated with risk of trastuzumab cardiotoxicity.BMC Cancer2015
25847941EMERGE: A Randomized Phase II Study of the Antibody-Drug Conjugate Glembatumumab Vedotin in Advanced Glycoprotein NMB-Expressing Breast Cancer.J Clin Oncol2015
25944802First-in-Human Trial of a Novel Anti-Trop-2 Antibody-SN-38 Conjugate, Sacituzumab Govitecan, for the Treatment of Diverse Metastatic Solid Tumors.Clin Cancer Res2015
25720743Menopause is a determinant of breast adipose inflammation.Cancer Prev Res (Phila)2015
25749072Efficacy of Scalp Cooling in Preventing Chemotherapy-Induced Alopecia in Breast Cancer Patients Receiving Adjuvant Docetaxel and Cyclophosphamide Chemotherapy.Clin Breast Cancer2015
25459070Disease-free survival according to the use of postmastectomy radiation therapy after neoadjuvant chemotherapy.Clin Breast Cancer2015
24202699Isolation of breast cancer and gastric cancer circulating tumor cells by use of an anti HER2-based microfluidic device.Lab Chip2014
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Collaborators

Leeds Teaching Hospitals NHS Trust, University of Leeds
Co-authored papers 7
Massachusetts General Hospital Cancer Center
Co-authored papers 6
Weill Cornell Medical College
Co-authored papers 6
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Vanderbilt University Medical Center
Co-authored papers 5
The University of Texas M.D. Anderson Cancer Center, American University of Beirut
Co-authored papers 5
Memorial Sloan Kettering Cancer Center, USA American Society of Clinical Oncology
Co-authored papers 5
Dana-Farber Cancer Institute
Co-authored papers 4
The University of Texas MD Anderson Cancer Center
Co-authored papers 4
National Cancer Institute
Co-authored papers 4
Massachusetts General Hospital
Co-authored papers 4
New York Presbyterian Hospital
Co-authored papers 4
Co-authored papers 3
University of Colorado Anschutz Medical Campus
Co-authored papers 3
Dana-Farber Cancer Institute
Co-authored papers 3
New York-Presbyterian Hospital
Co-authored papers 3
Weill Cornell University
Co-authored papers 3
Meyer Cancer Center
Co-authored papers 3
Cleveland Clinic.
Co-authored papers 3
Memorial Sloan Kettering Cancer Center
Co-authored papers 3
German Cancer Research Center (DKFZ)
Co-authored papers 2
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Caryl and Israel Englander Institute for Precision Medicine
Co-authored papers 2
Champalimaud Clinical Center/Champalimaud Foundation
Co-authored papers 2
Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
Co-authored papers 2
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Jill Roberts Institute for Research in Inflammatory Bowel Disease, Cornell University
Co-authored papers 2
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Yale School of Medicine
Co-authored papers 2
Co-authored papers 2