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Author Details

Laura Ru??
Department of Pharmaceutical and Pharmacological Sciences
2007
23
13
PMIDPaper TitleJournal TitlePublished Year
37376196Novel Human/Non-Human Primate Cross-Reactive Anti-Transferrin Receptor Nanobodies for Brain Delivery of Biologics.Pharmaceutics2023
36192747VHHs as tools for therapeutic protein delivery to the central nervous system.Fluids Barriers CNS2022
33614825AAV9-mediated gene delivery of MCT1 to oligodendrocytes does not provide a therapeutic benefit in a mouse model of ALS.Mol Ther Methods Clin Dev2021
31814004Environmental enrichment during the chronic phase after experimental stroke promotes functional recovery without synergistic effects of EphA4 targeted therapy.Hum Mol Genet2020
30852969Heterozygous Deletion of EphrinA5 Does Not Improve Functional Recovery After Experimental Stroke.Stroke2019
31803009Lowering EphA4 Does Not Ameliorate Disease in a Mouse Model for Severe Spinal Muscular Atrophy.Front Neurosci2019
31831046EphA4 loss improves social memory performance and alters dendritic spine morphology without changes in amyloid pathology in a mouse model of Alzheimer's disease.Alzheimers Res Ther2019
31300041Reduction of ephrin-A5 aggravates disease progression in amyotrophic lateral sclerosis.Acta Neuropathol Commun2019
31575928Reducing EphA4 before disease onset does not affect survival in a mouse model of Amyotrophic Lateral Sclerosis.Sci Rep2019
29460266Increased Levels of Rictor Prevent Mutant Huntingtin-Induced Neuronal Degeneration.Mol Neurobiol2018
29415125Elongator subunit 3 (ELP3) modifies ALS through tRNA modification.Hum Mol Genet2018
28526745Identification and characterization of Nanobodies targeting the EphA4 receptor.J Biol Chem2017
25876513RTP801 Is Involved in Mutant Huntingtin-Induced Cell Death.Mol Neurobiol2016
27721240Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels.J Clin Invest2016
27063456Loss of striatal 90-kDa ribosomal S6 kinase (Rsk) is a key factor for motor, synaptic and transcription dysfunction in Huntington's disease.Biochim Biophys Acta2016
23896721Early down-regulation of PKCδ as a pro-survival mechanism in Huntington's disease.Neuromolecular Med2014
25017368Translating biological findings into new treatment strategies for amyotrophic lateral sclerosis (ALS).Exp Neurol2014
23295856Brain region- and age-dependent dysregulation of p62 and NBR1 in a mouse model of Huntington's disease.Neurobiol Dis2013
23686490Reciprocal negative cross-talk between liver X receptors (LXRs) and STAT1: effects on IFN-γ-induced inflammatory responses and LXR-dependent gene expression.J Immunol2013
21632937Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity.J Neurosci2011
22041125Increased 90-kDa ribosomal S6 kinase (Rsk) activity is protective against mutant huntingtin toxicity.Mol Neurodegener2011
17336373Emergency Department education improves patient knowledge of coronary artery disease risk factors but not the accuracy of their own risk perception.Prev Med2007
17974027Prevalence and demographics of methicillin resistant Staphylococcus aureus in culturable skin and soft tissue infections in an urban emergency department.BMC Emerg Med2007
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Collaborators

Christopher J Lindsell
Duke University
Co-authored papers 2
Amy B Kressel
Indiana University School of Medicine
Co-authored papers 1
Andra L Blomkalns
Stanford University
Co-authored papers 1
Sabrina D Leach
Co-authored papers 1
Sebastian Munck
Co-authored papers 1
Annette Williams
Wilford Hall Medical Center
Co-authored papers 1
Christian H Jacobus
Central Michigan University College of Medicine
Co-authored papers 1
Xavier Estivill
Sidra Medical Center
Co-authored papers 1
Gregory J Fermann
University of Cincinnati
Co-authored papers 1
Release 1.2