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Author Details

Martin E Tanner
University of British Columbia
1993
66
28
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37069132Aldehyde-Based Inhibitors of the Peptidoglycan O-Acetylesterase Ape.Chembiochem2023
35560956Recent Advances in the Synthesis and Biological Applications of Peptidoglycan Fragments.Chemistry2022
35579270Phosphinic acid-based inhibitors of tubulin polyglycylation.Chem Commun (Camb)2022
33711341Peptidoglycan binding by a pocket on the accessory NTF2-domain of Pgp2 directs helical cell shape of Campylobacter jejuni.J Biol Chem2021
32133861Synthesis of a <i>meso</i>-Oxa-Diaminopimelic Acid Containing Peptidoglycan Pentapeptide and Coupling to the GlcNAc-<i>anhydro</i>-MurNAc Disaccharide.Org Lett2020
32792670Author Correction: Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes.Nat Struct Mol Biol2020
32979487A guanidinium-based inhibitor of a type I isopentenyl diphosphate isomerase.Bioorg Med Chem Lett2020
32432293ArnD is a deformylase involved in polymyxin resistance.Chem Commun (Camb)2020
30746833Peptides Containing meso-Oxa-Diaminopimelic Acid as Substrates for the Cell-Shape-Determining Proteases Csd6 and Pgp2.Chembiochem2019
30179505Studies with Guanidinium- and Amidinium-Based Inhibitors Suggest Minimal Stabilization of Allylic Carbocation Intermediates by Dehydrosqualene and Squalene Synthases.Biochemistry2018
26735022A Bacterial Cell Shape-Determining Inhibitor.ACS Chem Biol2016
25270661Mechanistic studies on the indole prenyltransferases.Nat Prod Rep2015
26207293Increasing the Diversity of Known Pictet-Spenglerases.Chem Biol2015
25505267Helical shape of Helicobacter pylori requires an atypical glutamine as a zinc ligand in the carboxypeptidase Csd4.J Biol Chem2015
24992358A methyltransferase initiates terpene cyclization in teleocidin B biosynthesis.J Am Chem Soc2014
23777780Phosphinic acid-based inhibitors of tubulin polyglutamylases.Bioorg Med Chem Lett2013
24251551Structure of MurNAc 6-phosphate hydrolase (MurQ) from Haemophilus influenzae with a bound inhibitor.Biochemistry2013
23972005Deamination of 6-aminodeoxyfutalosine in menaquinone biosynthesis by distantly related enzymes.Biochemistry2013
24014462Potential rearrangements in the reaction catalyzed by the indole prenyltransferase FtmPT1.Chembiochem2013
23611437Crystal structure of the capsular polysaccharide synthesizing protein CapE of Staphylococcus aureus.Biosci Rep2013
22235128Structure/function analysis of Pasteurella multocida heparosan synthases: toward defining enzyme specificity and engineering novel catalysts.J Biol Chem2012
22935004Mechanistic studies on CymD: a tryptophan reverse N-prenyltransferase.Biochemistry2012
212730696''-Azido-6''-deoxy-UDP-N-acetylglucosamine as a glycosyltransferase substrate.Bioorg Med Chem Lett2011
21766851A cope rearrangement in the reaction catalyzed by dimethylallyltryptophan synthase?J Am Chem Soc2011
214899955'-methylthioadenosine nucleosidase is implicated in playing a key role in a modified futalosine pathway for menaquinone biosynthesis in Campylobacter jejuni.J Biol Chem2011
21244065Water-soluble substrates of the peptidoglycan-modifying enzyme O-acetylpeptidoglycan esterase (Ape1) from Neisseria gonorrheae.J Org Chem2011
20506248The crystal structure of the Y140F mutant of ADP-L-glycero-D-manno-heptose 6-epimerase bound to ADP-beta-D-mannose suggests a one base mechanism.Protein Sci2010
19422007The engineering of bacteria bearing azido-pseudaminic acid-modified flagella.Chembiochem2009
19719325Inhibition of Neisseria meningitidis sialic acid synthase by a tetrahedral intermediate analogue.Biochemistry2009
19743851Mechanism of dimethylallyltryptophan synthase: evidence for a dimethylallyl cation intermediate in an aromatic prenyltransferase reaction.J Am Chem Soc2009
18275154Biosynthesis of CMP-N,N'-diacetyllegionaminic acid from UDP-N,N'-diacetylbacillosamine in Legionella pneumophila.Biochemistry2008
18845311Mechanistic studies on PseB of pseudaminic acid biosynthesis: a UDP-N-acetylglucosamine 5-inverting 4,6-dehydratase.Bioorg Chem2008
18837509Mechanistic studies on N-acetylmuramic acid 6-phosphate hydrolase (MurQ): an etherase involved in peptidoglycan recycling.Biochemistry2008
19053199Mechanism and active site residues of GDP-fucose synthase.J Am Chem Soc2008
18625333Transient oxidation as a mechanistic strategy in enzymatic catalysis.Curr Opin Chem Biol2008
17455913Intermediate release by ADP-L-glycero-D-manno-heptose 6-epimerase.Biochemistry2007
17696451Mechanistic studies on norcoclaurine synthase of benzylisoquinoline alkaloid biosynthesis: an enzymatic Pictet-Spengler reaction.Biochemistry2007
17316025A two-base mechanism for Escherichia coli ADP-L-glycero-D-manno-heptose 6-epimerase.Biochemistry2007
16728396PseG of pseudaminic acid biosynthesis: a UDP-sugar hydrolase as a masked glycosyltransferase.J Biol Chem2006
15516336Structural and mechanistic analysis of sialic acid synthase NeuB from Neisseria meningitidis in complex with Mn2+, phosphoenolpyruvate, and N-acetylmannosaminitol.J Biol Chem2005
16120604Identification and characterization of NeuB3 from Campylobacter jejuni as a pseudaminic acid synthase.J Biol Chem2005
15932222Efficient chemoenzymatic synthesis of ADP-D-glycero-beta-D-manno-heptose and a mechanistic study of ADP-L-glycero-D-manno-heptose 6-epimerase.Org Lett2005
15823050Dismutase activity of ADP-L-glycero-D-manno-heptose 6-epimerase: evidence for a direct oxidation/reduction mechanism.Biochemistry2005
15888312The enzymes of sialic acid biosynthesis.Bioorg Chem2005
14686915Active site residues and mechanism of UDP-glucose dehydrogenase.Eur J Biochem2004
15264802The mechanism of the reaction catalyzed by ADP-beta-L-glycero-D-manno-heptose 6-epimerase.J Am Chem Soc2004
15210128Active site mutants of the "non-hydrolyzing" UDP-N-acetylglucosamine 2-epimerase from Escherichia coli.Biochim Biophys Acta2004
15518580Identification and mechanism of a bacterial hydrolyzing UDP-N-acetylglucosamine 2-epimerase.Biochemistry2004
14729696The NeuC protein of Escherichia coli K1 is a UDP N-acetylglucosamine 2-epimerase.J Bacteriol2004
12603133Sialic acid biosynthesis: stereochemistry and mechanism of the reaction catalyzed by the mammalian UDP-N-acetylglucosamine 2-epimerase.J Am Chem Soc2003
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Collaborators

Natalie C J Strynadka
The University of British Columbia
Co-authored papers 6
Xu Li
University of British Columbia
Co-authored papers 2
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Alissa M Goble
Texas A&M University , College Station
Co-authored papers 1
Ronald D Seidel
Albert Einstein College of Medicine
Co-authored papers 1
Hao Fan
College of Biotechnology and Bioengineering, Zhejiang University of Technology
Co-authored papers 1
Argentina Ornelas
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Rafael Toro
Medical College of Wisconsin
Co-authored papers 1
Brian K Shoichet
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 1
Brandan Hillerich
Cue BioPharma Inc.
Co-authored papers 1
Robert J Linhardt
Rensselaer Polytechnic Institute
Co-authored papers 1
Subramaniam Eswaramoorthy
Brookhaven National Laboratory
Co-authored papers 1
Subramanyam Swaminathan
Brookhaven National Laboratory
Co-authored papers 1
Frank M Raushel
Texas A&M University, College Station
Co-authored papers 1
Yury Patskovsky
New York University Grossman School of Medicine
Co-authored papers 1
Steven C Almo
Albert Einstein College of Medicine
Co-authored papers 1
Release 1.2