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Author Details

Michael G Rosenfeld
University of California San Diego
1963
484
175
PMIDPaper TitleJournal TitlePublished Year
36747093Signal-induced enhancer activation requires Ku70 to read topoisomerase1-DNA covalent complexes.Nat Struct Mol Biol2023
37751740RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression.Mol Cell2023
37345431Identification and functional validation of an enhancer variant in the 9p21.3 locus associated with glaucoma risk and elevated expression of p16<sup>INK4a</sup>.Aging Cell2023
36747093Signal-induced enhancer activation requires Ku70 to read topoisomerase1-DNA covalent complexes.Nat Struct Mol Biol2023
37751740RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression.Mol Cell2023
37345431Identification and functional validation of an enhancer variant in the 9p21.3 locus associated with glaucoma risk and elevated expression of p16<sup>INK4a</sup>.Aging Cell2023
35914133Long-distance association of topological boundaries through nuclear condensates.Proc Natl Acad Sci U S A2022
35914133Long-distance association of topological boundaries through nuclear condensates.Proc Natl Acad Sci U S A2022
35811173Transcriptional enhancers at 40: evolution of a viral DNA element to nuclear architectural structures.Trends Genet2022
35790797Author Correction: Transcriptional regulation of a metastasis suppressor gene by Tip60 and β-catenin complexes.Nature2022
35790797Author Correction: Transcriptional regulation of a metastasis suppressor gene by Tip60 and β-catenin complexes.Nature2022
35811173Transcriptional enhancers at 40: evolution of a viral DNA element to nuclear architectural structures.Trends Genet2022
32876528The DNA methyltransferase DNMT3A contributes to autophagy long-term memory.Autophagy2021
34163071A transcriptional switch governs fibroblast activation in heart disease.Nature2021
34040254Enhancer release and retargeting activates disease-susceptibility genes.Nature2021
33658690Hippo signalling maintains ER expression and ER<sup>+</sup> breast cancer growth.Nature2021
34194047Shape of promoter antisense RNAs regulates ligand-induced transcription activation.Nature2021
33977073The Dual Function of KDM5C in Both Gene Transcriptional Activation and Repression Promotes Breast Cancer Cell Growth and Tumorigenesis.Adv Sci (Weinh)2021
34324630An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation.Blood2021
32876528The DNA methyltransferase DNMT3A contributes to autophagy long-term memory.Autophagy2021
34529725A comprehensive integrated post-GWAS analysis of Type 1 diabetes reveals enhancer-based immune dysregulation.PLoS One2021
33658690Hippo signalling maintains ER expression and ER<sup>+</sup> breast cancer growth.Nature2021
34529725A comprehensive integrated post-GWAS analysis of Type 1 diabetes reveals enhancer-based immune dysregulation.PLoS One2021
34324630An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation.Blood2021
34040254Enhancer release and retargeting activates disease-susceptibility genes.Nature2021
33977073The Dual Function of KDM5C in Both Gene Transcriptional Activation and Repression Promotes Breast Cancer Cell Growth and Tumorigenesis.Adv Sci (Weinh)2021
34194047Shape of promoter antisense RNAs regulates ligand-induced transcription activation.Nature2021
34163071A transcriptional switch governs fibroblast activation in heart disease.Nature2021
32315832Reorganized 3D Genome Structures Support Transcriptional Regulation in Mouse Spermatogenesis.iScience2020
32315832Reorganized 3D Genome Structures Support Transcriptional Regulation in Mouse Spermatogenesis.iScience2020
32350257LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development.Nat Commun2020
32169215Initiation of Parental Genome Reprogramming in Fertilized Oocyte by Splicing Kinase SRPK1-Catalyzed Protamine Phosphorylation.Cell2020
32933333Signalosome-Regulated Serum Response Factor Phosphorylation Determining Myocyte Growth in Width Versus Length as a Therapeutic Target for Heart Failure.Circulation2020
32817485Global epigenomic analysis of KSHV-infected primary effusion lymphoma identifies functional <i>MYC</i> superenhancers and enhancer RNAs.Proc Natl Acad Sci U S A2020
32579929Enhancer RNAs Mediate Estrogen-Induced Decommissioning of Selective Enhancers by Recruiting ERα and Its Cofactor.Cell Rep2020
32579929Enhancer RNAs Mediate Estrogen-Induced Decommissioning of Selective Enhancers by Recruiting ERα and Its Cofactor.Cell Rep2020
32933333Signalosome-Regulated Serum Response Factor Phosphorylation Determining Myocyte Growth in Width Versus Length as a Therapeutic Target for Heart Failure.Circulation2020
32817485Global epigenomic analysis of KSHV-infected primary effusion lymphoma identifies functional <i>MYC</i> superenhancers and enhancer RNAs.Proc Natl Acad Sci U S A2020
32350257LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development.Nat Commun2020
32169215Initiation of Parental Genome Reprogramming in Fertilized Oocyte by Splicing Kinase SRPK1-Catalyzed Protamine Phosphorylation.Cell2020
30833784Phase separation of ligand-activated enhancers licenses cooperative chromosomal enhancer assembly.Nat Struct Mol Biol2019
31727856Brain cell type-specific enhancer-promoter interactome maps and disease<b>-</b>risk association.Science2019
31570892Allele-specific NKX2-5 binding underlies multiple genetic associations with human electrocardiographic traits.Nat Genet2019
30833784Phase separation of ligand-activated enhancers licenses cooperative chromosomal enhancer assembly.Nat Struct Mol Biol2019
31727856Brain cell type-specific enhancer-promoter interactome maps and disease<b>-</b>risk association.Science2019
31570892Allele-specific NKX2-5 binding underlies multiple genetic associations with human electrocardiographic traits.Nat Genet2019
29263096Histone demethylase LSD1 regulates hematopoietic stem cells homeostasis and protects from death by endotoxic shock.Proc Natl Acad Sci U S A2018
30118678Dismissal of RNA Polymerase II Underlies a Large Ligand-Induced Enhancer Decommissioning Program.Mol Cell2018
30193100The Akt-SRPK-SR Axis Constitutes a Major Pathway in Transducing EGF Signaling to Regulate Alternative Splicing in the Nucleus.Mol Cell2018
29628309JMJD6 Licenses ERα-Dependent Enhancer and Coding Gene Activation by Modulating the Recruitment of the CARM1/MED12 Co-activator Complex.Mol Cell2018
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Center for Epigenomics, University of California San Diego
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Minna U Kaikkonen
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Juan Carlos Izpisua Belmonte
Inc., Salk Institute for Biological Studies
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Andres Ramos
Institute of Structural and Molecular Biology (ISMB), University College London
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Inder M Verma
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Wendy Huang
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Pieter C Dorrestein
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Release 1.2