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Author Details

Blaise A Clarke
University of Toronto.
2001
149
49
PMIDPaper TitleJournal TitlePublished Year
37867306Targeted RNA Sequencing Highlights a Diverse Genomic and Morphologic Landscape in Low-grade Endometrial Stromal Sarcoma, Including Novel Fusion Genes.Am J Surg Pathol2024
36583307Well-differentiated Sertoli-Leydig Cell Tumors (SLCTs) Are Not Associated With DICER1 Pathogenic Variants and Represent a Different Tumor Type to Moderately and Poorly Differentiated SLCTs.Am J Surg Pathol2023
36943460Identification of antigenic epitopes recognized by tumor infiltrating lymphocytes in high grade serous ovarian cancer by multi-omics profiling of the auto-antigen repertoire.Cancer Immunol Immunother2023
36966138Genomic characterization of DICER1-associated neoplasms uncovers molecular classes.Nat Commun2023
36922497Clinical outcome and biomarker assessments of a multi-centre phase II trial assessing niraparib with or without dostarlimab in recurrent endometrial carcinoma.Nat Commun2023
35012974Brief family history questionnaire to screen for Lynch syndrome in women with newly diagnosed non-serous, non-mucinous ovarian cancers.Int J Gynecol Cancer2022
35501919Impact of neoadjuvant chemotherapy on somatic mutation status in high-grade serous ovarian carcinoma.J Ovarian Res2022
35575789Recurrent KAT6B/A::KANSL1 Fusions Characterize a Potentially Aggressive Uterine Sarcoma Morphologically Overlapping With Low-grade Endometrial Stromal Sarcoma.Am J Surg Pathol2022
36040033Ovarian Signet-ring Stromal Tumor: A Morphologic, Immunohistochemical, and Molecular Study of 7 Cases With Discussion of the Differential Diagnosis.Am J Surg Pathol2022
32265358Equivalent Survival of p53 Mutated Endometrial Endometrioid Carcinoma Grade 3 and Endometrial Serous Carcinoma.Int J Gynecol Pathol2021
33718561Can <i>TP53</i> variant negative be high-grade serous ovarian carcinoma? A case series.Gynecol Oncol Rep2021
33793971Evaluation of treatment effects in patients with endometrial cancer and POLE mutations: An individual patient data meta-analysis.Cancer2021
33838572Endometrial Stem/Progenitor cell (ES/PC) Marker Expression Profile in Adenosarcoma and Endometrial Stromal Sarcoma.Cancer Treat Res Commun2021
34157791Validation of BRCA testing on cytologic samples of high-grade serous carcinoma.Cancer Cytopathol2021
33983630Maximizing cancer prevention through genetic navigation for Lynch syndrome detection in women with newly diagnosed endometrial and nonserous/nonmucinous epithelial ovarian cancer.Cancer2021
34115671Corded and Hyalinized and Spindled Endometrioid Endometrial Carcinoma: A Clinicopathologic and Molecular Analysis of 9 Tumors Based on the TCGA Classifier.Am J Surg Pathol2021
33030818Tumor and germline next generation sequencing in high grade serous cancer: experience from a large population-based testing program.Mol Oncol2021
33478752Understanding the clinical implication of mismatch repair deficiency in endometrioid endometrial cancer through a prospective study.Gynecol Oncol2021
33175109Assessment of Sentinel Lymph Node Biopsy vs Lymphadenectomy for Intermediate- and High-Grade Endometrial Cancer Staging.JAMA Surg2021
33259954An Integrative DNA Sequencing and Methylation Panel to Assess Mismatch Repair Deficiency.J Mol Diagn2021
33021556The Value of DICER1 Mutation Analysis in "Subtle" Diagnostically Challenging Embryonal Rhabdomyosarcomas of the Uterine Cervix.Int J Gynecol Pathol2021
32980858Interpretation of mismatch repair protein expression using obsolete criteria results in discrepancies with microsatellite instability and mutational testing results. Comment on Hechtman et al. Mod Pathol 2020; 33:871-879.Mod Pathol2021
31274700HPV-independent Vulvar Squamous Cell Carcinoma is Associated With Significantly Worse Prognosis Compared With HPV-associated Tumors.Int J Gynecol Pathol2020
31964625IL6 Induces an IL22<sup>+</sup> CD8<sup>+</sup> T-cell Subset with Potent Antitumor Function.Cancer Immunol Res2020
33082239Tumor site discordance in mismatch repair deficiency in synchronous endometrial and ovarian cancers.Int J Gynecol Cancer2020
32809219Performance characteristics of screening strategies to identify Lynch syndrome in women with ovarian cancer.Cancer2020
32912664Biomarkers of outcome to weekly paclitaxel in epithelial ovarian cancer.Gynecol Oncol2020
32281774Interlaboratory Concordance of ProMisE Molecular Classification of Endometrial Carcinoma Based on Endometrial Biopsy Specimens.Int J Gynecol Pathol2020
32434219Distinct fibroblast functional states drive clinical outcomes in ovarian cancer and are regulated by TCF21.J Exp Med2020
29521846International Society of Gynecological Pathologists (ISGyP) Endometrial Cancer Project: Guidelines From the Special Techniques and Ancillary Studies Group.Int J Gynecol Pathol2019
31803363Avoidance of apoptotic death via a hyperploid salvage survival pathway after platinum treatment in high grade serous carcinoma cell line models.Oncotarget2019
31892360High expression of B7-H3 on stromal cells defines tumor and stromal compartments in epithelial ovarian cancer and is associated with limited immune activation.J Immunother Cancer2019
31741762Tumor cell expression of B7-H4 correlates with higher frequencies of tumor-infiltrating APCs and higher CXCL17 expression in human epithelial ovarian cancer.Oncoimmunology2019
31308508Molecular characterization of gastric-type endocervical adenocarcinoma using next-generation sequencing.Mod Pathol2019
30981729N-Glycoproteomics of Patient-Derived Xenografts: A Strategy to Discover Tumor-Associated Proteins in High-Grade Serous Ovarian Cancer.Cell Syst2019
31010432Metastatic low-grade endometrial stromal sarcoma of uterus presenting as a primary pancreatic tumor: case presentation and literature review.Diagn Pathol2019
30792002Impact of somatic molecular profiling on clinical trial outcomes in rare epithelial gynecologic cancer patients.Gynecol Oncol2019
30718512CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary.Nat Commun2019
30325056Expanding the morphological spectrum of ovarian microcystic stromal tumour.Histopathology2019
30670562Neoadjuvant therapy in gynaecological malignancies: What pathologists need to know.J Clin Pathol2019
30659026<i>TP53</i> mutations in high grade serous ovarian cancer and impact on clinical outcomes: a comparison of next generation sequencing and bioinformatics analyses.Int J Gynecol Cancer2019
29145543Association of Ipilimumab With Safety and Antitumor Activity in Women With Metastatic or Recurrent Human Papillomavirus-Related Cervical Carcinoma.JAMA Oncol2018
30065096Regulatory T Cells in Ovarian Cancer Are Characterized by a Highly Activated Phenotype Distinct from that in Melanoma.Clin Cancer Res2018
30108107A Clinical and Molecular Phase II Trial of Oral ENMD-2076 in Ovarian Clear Cell Carcinoma (OCCC): A Study of the Princess Margaret Phase II Consortium.Clin Cancer Res2018
30382883Landscape of genomic alterations in high-grade serous ovarian cancer from exceptional long- and short-term survivors.Genome Med2018
29449057Prognostic Significance of Human Papilloma Virus and p16 Expression in Patients with Vulvar Squamous Cell Carcinoma who Received Radiotherapy.Clin Oncol (R Coll Radiol)2018
29416878Genomic profiling identifies <i>GPC5</i> amplification in association with sarcomatous transformation in a subset of uterine carcinosarcomas.J Pathol Clin Res2018
29458007A Genomically Characterized Collection of High-Grade Serous Ovarian Cancer Xenografts for Preclinical Testing.Am J Pathol2018
29287922Gynaecological neoplasms in common familial syndromes (Lynch and HBOC).Pathology2018
29076875Ovarian Microcystic Stromal Tumors Are Characterized by Alterations in the Beta-Catenin-APC Pathway and May be an Extracolonic Manifestation of Familial Adenomatous Polyposis.Am J Surg Pathol2018
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Collaborators

Patricia A Shaw
Princess Margaret Cancer Centre, University Avenue
Co-authored papers 33
Cyril B Gilks
University of British Columbia
Co-authored papers 32
David G Huntsman
University of British Columbia
Co-authored papers 17
William D Foulkes
Segal Cancer Centre, Jewish General Hospital
Co-authored papers 16
Aaron Pollett
Mount Sinai Hospital
Co-authored papers 14
Martin K??bel
University of Calgary
Co-authored papers 14
Steve E Kalloger
University of British Columbia
Co-authored papers 13
Steven Gallinger
Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto
Co-authored papers 12
Trevor J Pugh
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 12
Michael Milosevic
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 11
Melania Pintilie
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 10
Suzanne Kamel-Reid
Toronto General Hospital, University Health Network, University of Toronto
Co-authored papers 9
Anthony Fyles
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 9
Lillian L Siu
Princess Margaret Cancer Centre, University Ave
Co-authored papers 8
Richard P Hill
Princess Margaret Cancer Centre
Co-authored papers 8
Raymond H Kim
Cardiac Genome Clinic, The Hospital for Sick Children
Co-authored papers 8
Ghassan Allo
Henry Ford Hospital
Co-authored papers 7
Philippe L Bedard
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 7
Fei-Fei Liu
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 5
Stephen Welch
Victoria Hospital
Co-authored papers 5
Paul C Boutros
University of California los angeles
Co-authored papers 5
Christine How
Ontario Cancer Institute, University Health Network (UHN)
Co-authored papers 5
Bayardo Perez-Ordonez
University Health Network
Co-authored papers 5
Jeff P Bruce
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 5
Michael S Anglesio
University of British Columbia
Co-authored papers 4
Janine Senz
University of British Columbia
Co-authored papers 4
David W Hedley
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 4
Sohrab P Shah
Memorial Sloan Kettering Cancer Center
Co-authored papers 4
David D L Bowtell
Peter MacCallum Cancer Centre
Co-authored papers 4
Ming-Sound Tsao
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