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Author Details

Guibin Chen
and Blood Institute, National Institutes of Health
2001
55
27
Prashant Mali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36932076Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome.Nat Commun2023
38026202Derived myeloid lineage induced pluripotent stem as a platform to study human C-C chemokine receptor type 5ο32 homozygotes.iScience2023
37610273A Protocol for Culture and Characterization of Human Induced Pluripotent Stem Cells After Induction.Curr Protoc2023
37310585Mast cell activation and degranulation in acute artery injury: A target for post-operative therapy.FASEB J2023
36550275Bioprinted 3D outer retina barrier uncovers RPE-dependent choroidal phenotype in advanced macular degeneration.Nat Methods2023
36921440Corrigendum to "Human induced pluripotent stem cells generated from a patient with a homozygous mutation in the Lyn kinase gene" [Stem Cell Res. 64 (2022) 102933].Stem Cell Res2023
36215934Human induced pluripotent stem cells generated from a patient with a homozygous mutation in the Lyn kinase gene.Stem Cell Res2022
35660921Human induced pluripotent stem cells generated from Chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature (CANDLE) syndrome patients with a homozygous mutation in the PSMB8 gene (NIHTVBi016-A, NIHTVBi017-A, NIHTVBi018-A).Stem Cell Res2022
365824113D printed biomimetic flexible blood vessels with iPS cell-laden hierarchical multilayers.Biomed Eng Adv2022
36399927Human induced pluripotent stem cells generated from STING-associated vasculopathy with onset in infancy (SAVI) patients with a heterozygous mutation in the STING gene.Stem Cell Res2022
32369445Impaired angiogenesis and extracellular matrix metabolism in autosomal-dominant hyper-IgE syndrome.J Clin Invest2020
32580970STAT3 modulates reprogramming efficiency of human somatic cells; insights from autosomal dominant Hyper IgE syndrome caused by STAT3 mutations.Biol Open2020
32721894Human induced pluripotent stem cells generated from a patient with a homozygous L272P mutation in the OTULIN gene (NIHTVBi014-A).Stem Cell Res2020
32119531Stem Cell-Derived Endothelial Cell Model that Responds to Tobacco Smoke Like Primary Endothelial Cells.Chem Res Toxicol2020
32344328Generation of human induced pluripotent stem cells (NIHTVBi004-A, NIHTVBi005-A, NIHTVBi006-A, NIHTVBi007-A, NIHTVBi008-A) from 5 CADASIL patients with NOTCH3 mutation.Stem Cell Res2020
30651639Human blood vessel organoids as a model of diabetic vasculopathy.Nature2019
31710911Robust generation of erythroid and multilineage hematopoietic progenitors from human iPSCs using a scalable monolayer culture system.Stem Cell Res2019
31707214Generation of human induced pluripotent stem cell lines (NIHTVBi011-A, NIHTVBi012-A, NIHTVBi013-A) from autosomal dominant Hyper IgE syndrome (AD-HIES) patients carrying STAT3 mutation.Stem Cell Res2019
31234109Generation of human induced pluripotent stem cells from individuals with a homozygous CCR5ο32 mutation.Stem Cell Res2019
29651156Efficient differentiation of cardiomyocytes and generation of calcium-sensor reporter lines from nonhuman primate iPSCs.Sci Rep2018
29873142High Basal Levels of γH2AX in Human Induced Pluripotent Stem Cells Are Linked to Replication-Associated DNA Damage and Repair.Stem Cells2018
27965423Increased activity of TNAP compensates for reduced adenosine production and promotes ectopic calcification in the genetic disease ACDC.Sci Signal2016
24622514TGF-β signaling mediates endothelial-to-mesenchymal transition (EndMT) during vein graft remodeling.Sci Transl Med2014
24925468Stem cell-derived motor neurons from spinal and bulbar muscular atrophy patients.Neurobiol Dis2014
24881868Self-renewal and cell lineage differentiation strategies in human embryonic stem cells and induced pluripotent stem cells.Expert Opin Biol Ther2014
24515897Genetics of low spinal muscular atrophy carrier frequency in sub-Saharan Africa.Ann Neurol2014
24113066Generation of glycosylphosphatidylinositol anchor protein-deficient blood cells from human induced pluripotent stem cells.Stem Cells Transl Med2013
22093062The benefits and risks of stem cell technology.Oral Dis2012
20038813Stat3-dependent acute Rantes production in vascular smooth muscle cells modulates inflammation following arterial injury in mice.J Clin Invest2010
20629173Major histocompatibility complex-I expression on embryonic stem cell-derived vascular progenitor cells is critical for syngeneic transplant survival.Stem Cells2010
19013003Glycosylphosphatidylinositol-anchored protein deficiency confers resistance to apoptosis in PNH.Exp Hematol2009
19540188Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells.Cell Stem Cell2009
18397754Trophoblast differentiation defect in human embryonic stem cells lacking PIG-A and GPI-anchored cell-surface proteins.Cell Stem Cell2008
18462696Notch signaling activation in human embryonic stem cells is required for embryonic, but not trophoblastic, lineage commitment.Cell Stem Cell2008
18511599Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts.Stem Cells2008
18596037Combinatorial signals of activin/nodal and bone morphogenic protein regulate the early lineage segregation of human embryonic stem cells.J Biol Chem2008
17158240Inducible and reversible transgene expression in human stem cells after efficient and stable gene transfer.Stem Cells2007
17885215Fractalkine upregulates intercellular adhesion molecule-1 in endothelial cells through CX3CR1 and the Jak Stat5 pathway.Circ Res2007
17090657CD34 cells from patients with trisomy 8 myelodysplastic syndrome (MDS) express early apoptotic markers but avoid programmed cell death by up-regulation of antiapoptotic proteins.Blood2007
16131564Interferon-gamma-induced gene expression in CD34 cells: identification of pathologic cytokine-specific signature profiles.Blood2006
15759038Differential gene expression in hematopoietic progenitors from paroxysmal nocturnal hemoglobinuria patients reveals an apoptosis/immune response in 'normal' phenotype cells.Leukemia2005
16002782Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells.Stem Cells2005
14504100Gene expression profiling in CD34 cells to identify differences between aplastic anemia patients and healthy volunteers.Blood2004
15315976Distinctive gene expression profiles of CD34 cells from patients with myelodysplastic syndrome characterized by specific chromosomal abnormalities.Blood2004
15345281Transcript profile of CD4+ and CD8+ T cells from the bone marrow of acquired aplastic anemia patients.Exp Hematol2004
15086421Frequent HPRT mutations in paroxysmal nocturnal haemoglobinuria reflect T cell clonal expansion, not genomic instability.Br J Haematol2004
15167913Is there a direct effect of antithymocyte globulin on hematopoiesis?Hematol J2004
12543108CD34+ cells from paroxysmal nocturnal hemoglobinuria (PNH) patients are deficient in surface expression of cellular prion protein (PrPc).Exp Hematol2003
12070025Oligoclonal and polyclonal CD4 and CD8 lymphocytes in aplastic anemia and paroxysmal nocturnal hemoglobinuria measured by V beta CDR3 spectratyping and flow cytometry.Blood2002
12135676Superior growth of glycophosphatidy linositol-anchored protein-deficient progenitor cells in vitro is due to the higher apoptotic rate of progenitors with normal phenotype in vivo.Exp Hematol2002
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Collaborators

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Co-authored papers 16
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Co-authored papers 13
Johns Hopkins University School of Medicine
Co-authored papers 9
and Blood Institute, National Institutes of Health
Co-authored papers 8
Center for Biologics Evaluation and Research
Co-authored papers 7
Heidelberg University
Co-authored papers 4
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University of California San Diego
Co-authored papers 4
Sidney Kimmel Cancer Center, Johns Hopkins University
Co-authored papers 3
Center for Pathogen Research, University of Maryland School of Medicine
Co-authored papers 2
National Institute of Allergy and Infectious Diseases
Co-authored papers 2
National Human Genome Research Institute, National Institutes of Health
Co-authored papers 2
Sidney Kimmel Cancer Center, Johns Hopkins University
Co-authored papers 1
Stanford University
Co-authored papers 1
National Cancer Institute, National Institutes of Health
Co-authored papers 1
National Institute on Aging
Co-authored papers 1
Livestrong Cancer Institutes, Dell Medical School, University of Texas at Austin
Co-authored papers 1
University of Fukui
Co-authored papers 1
The Johns Hopkins University School of Medicine
Co-authored papers 1
University of Macau
Co-authored papers 1
Yale School of Medicine
Co-authored papers 1
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 1
Memorial Sloan Kettering Cancer Center
Co-authored papers 1
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 1
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Amherst College
Co-authored papers 1
Co-authored papers 1
Shenzhen Alpha-biotechnology Inc. Shenzhen
Co-authored papers 1
University of California irvine
Co-authored papers 1