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Author Details
Full Name
Howard Y Chang
Affiliation
Center for Personal Dynamic Regulomes, Stanford University
ORCID
Career Start Year
1992
Papers
340
H Index
127
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
35978134
Author Correction: Engineering circular RNA for enhanced protein production.
Nat Biotechnol
2023
37587197
Whole genome deconvolution unveils Alzheimer's resilient epigenetic signature.
Nat Commun
2023
37503111
Coordinated inheritance of extrachromosomal DNA species in human cancer cells.
bioRxiv
2023
35851375
Engineering circular RNA for enhanced protein production.
Nat Biotechnol
2023
36993359
Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells.
bioRxiv
2023
37155869
Circular RNA vaccine induces potent T cell responses.
Proc Natl Acad Sci U S A
2023
37117181
The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner.
Nat Commun
2023
37046089
Extrachromosomal DNA in the cancerous transformation of Barrett's oesophagus.
Nature
2023
37142849
Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells.
Nat Genet
2023
37162993
Transcriptional immune suppression and upregulation of double stranded DNA damage and repair repertoires in ecDNA-containing tumors.
bioRxiv
2023
36736311
Reversing the Central Dogma: RNA-guided control of DNA in epigenetics and genome editing.
Mol Cell
2023
36865202
LINE-associated cryptic splicing induces dsRNA-mediated interferon response and tumor immunity.
bioRxiv
2023
36596869
Long non-coding RNAs: definitions, functions, challenges and recommendations.
Nat Rev Mol Cell Biol
2023
36658223
A guide to naming eukaryotic circular RNAs.
Nat Cell Biol
2023
34752712
Extrachromosomal DNA: An Emerging Hallmark in Human Cancer.
Annu Rev Pathol
2022
35410381
BRD2 compartmentalizes the accessible genome.
Nat Genet
2022
35398879
Oncogene Convergence in Extrachromosomal DNA Hubs.
Cancer Discov
2022
35695839
RNA-binding proteins direct myogenic cell fate decisions.
Elife
2022
35358469
Circular RNA migration in agarose gel electrophoresis.
Mol Cell
2022
35483375
Enhanced safety and efficacy of protease-regulated CAR-T cell receptors.
Cell
2022
35482398
A Genetic Bottleneck of Mitochondrial DNA During Human Lymphocyte Development.
Mol Biol Evol
2022
36516854
Engineered cell entry links receptor biology with single-cell genomics.
Cell
2022
36579891
Inducible lncRNA transgenic mice reveal continual role of <i>HOTAIR</i> in promoting breast cancer metastasis.
Elife
2022
36575212
The autism risk factor CHD8 is a chromatin activator in human neurons and functionally dependent on the ERK-MAPK pathway effector ELK1.
Sci Rep
2022
36277849
Single-cell multiome of the human retina and deep learning nominate causal variants in complex eye diseases.
Cell Genom
2022
35999210
KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress.
Nat Commun
2022
36270275
Multiomic analysis reveals conservation of cancer-associated fibroblast phenotypes across species and tissue of origin.
Cancer Cell
2022
36356142
Enhanced T cell effector activity by targeting the Mediator kinase module.
Science
2022
36123406
The evolutionary dynamics of extrachromosomal DNA in human cancers.
Nat Genet
2022
35948767
Gene regulation on extrachromosomal DNA.
Nat Struct Mol Biol
2022
35093191
Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility.
Neuron
2022
34971569
GPC2-CAR TÂ cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity.
Cancer Cell
2022
33442682
B cell-specific XIST complex enforces X-inactivation and restrains atypical B cells.
bioRxiv
2021
33827925
BABEL enables cross-modality translation between multiomic profiles at single-cell resolution.
Proc Natl Acad Sci U S A
2021
33795428
Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling.
Science
2021
33790476
Author Correction: ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis.
Nat Genet
2021
33735607
B cell-specific XIST complex enforces X-inactivation and restrains atypical B cells.
Cell
2021
33838111
Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing.
Cell
2021
33633365
ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis.
Nat Genet
2021
33833111
Recruiting T cells in cancer immunotherapy.
Science
2021
34859208
PEPATAC: an optimized pipeline for ATAC-seq data analysis with serial alignments.
NAR Genom Bioinform
2021
34906313
Toward a better understanding of TÂ cells in cancer.
Cancer Cell
2021
34791665
Noncoding RNAs: biology and applications-a Keystone Symposia report.
Ann N Y Acad Sci
2021
34437836
Structured elements drive extensive circular RNA translation.
Mol Cell
2021
34516825
JUN promotes hypertrophic skin scarring via CD36 in preclinical in vitro and in vivo models.
Sci Transl Med
2021
34485935
fSHAPE, fSHAPE-eCLIP, and SHAPE-eCLIP probe transcript regions that interact with specific proteins.
STAR Protoc
2021
34778803
NOT-Gated CD93 CAR T Cells Effectively Target AML with Minimized Endothelial Cross-Reactivity.
Blood Cancer Discov
2021
34390642
Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution.
Cell
2021
34620713
Integrated spatial multiomics reveals fibroblast fate during tissue repair.
Proc Natl Acad Sci U S A
2021
34593797
Chromatin accessibility associates with protein-RNA correlation in human cancer.
Nat Commun
2021
1 - 50 of 340
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