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Author Details

Mario L Suv??
Broad Institute of MIT and Harvard
2004
88
48
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37258682Hallmarks of transcriptional intratumour heterogeneity across a thousand tumours.Nature2023
37609137Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerability.bioRxiv2023
37853118Clinical trial links oncolytic immunoactivation to survival in glioblastoma.Nature2023
37914930Glioma synapses recruit mechanisms of adaptive plasticity.Nature2023
37961527Programs, Origins, and Niches of Immunomodulatory Myeloid Cells in Gliomas.bioRxiv2023
37961514DrugMap: A quantitative pan-cancer analysis of cysteine ligandability.bioRxiv2023
37258682Hallmarks of transcriptional intratumour heterogeneity across a thousand tumours.Nature2023
37914930Glioma synapses recruit mechanisms of adaptive plasticity.Nature2023
37961527Programs, Origins, and Niches of Immunomodulatory Myeloid Cells in Gliomas.bioRxiv2023
37961514DrugMap: A quantitative pan-cancer analysis of cysteine ligandability.bioRxiv2023
37853118Clinical trial links oncolytic immunoactivation to survival in glioblastoma.Nature2023
37609137Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerability.bioRxiv2023
36322658Single-cell multiomics identifies clinically relevant mesenchymal stem-like cells and key regulators for MPNST malignancy.Sci Adv2022
36305736BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma.Cancer Discov2022
36173860Oncometabolite d-2HG alters T cell metabolism to impair CD8<sup>+</sup> T cell function.Science2022
35706413Microenvironmental Landscape of Human Melanoma Brain Metastases in Response to Immune Checkpoint Inhibition.Cancer Immunol Res2022
36224665Correction: Elucidating the diversity of malignant mesenchymal states in glioblastoma by integrative analysis.Genome Med2022
36123598Elucidating the diversity of malignant mesenchymal states in glioblastoma by integrative analysis.Genome Med2022
35982179Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma.Nat Cancer2022
36322658Single-cell multiomics identifies clinically relevant mesenchymal stem-like cells and key regulators for MPNST malignancy.Sci Adv2022
36471067The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location.Nat Genet2022
35706413Microenvironmental Landscape of Human Melanoma Brain Metastases in Response to Immune Checkpoint Inhibition.Cancer Immunol Res2022
36471067The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location.Nat Genet2022
36173860Oncometabolite d-2HG alters T cell metabolism to impair CD8<sup>+</sup> T cell function.Science2022
36305736BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma.Cancer Discov2022
36224665Correction: Elucidating the diversity of malignant mesenchymal states in glioblastoma by integrative analysis.Genome Med2022
36123598Elucidating the diversity of malignant mesenchymal states in glioblastoma by integrative analysis.Genome Med2022
35982179Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma.Nat Cancer2022
33249504GLI3 Is Associated With Neuronal Differentiation in SHH-Activated and WNT-Activated Medulloblastoma.J Neuropathol Exp Neurol2021
33862619Re-evaluating Biopsy for Recurrent Glioblastoma: A Position Statement by the Christopher Davidson Forum Investigators.Neurosurgery2021
33811126Decoding Cancer Biology One Cell at a Time.Cancer Discov2021
33592174Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis.Cell2021
33681822Pathway-based classification of glioblastoma uncovers a mitochondrial subtype with therapeutic vulnerabilities.Nat Cancer2021
34215585A live single-cell reporter assay links intratumor heterogeneity to metastatic proclivity in Ewing sarcoma.Sci Adv2021
33720339Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles.Blood Adv2021
34087162Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma.Cancer Cell2021
33495604Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma.Nat Med2021
33249504GLI3 Is Associated With Neuronal Differentiation in SHH-Activated and WNT-Activated Medulloblastoma.J Neuropathol Exp Neurol2021
34594037Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states.Nat Genet2021
33720339Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles.Blood Adv2021
33681822Pathway-based classification of glioblastoma uncovers a mitochondrial subtype with therapeutic vulnerabilities.Nat Cancer2021
33592174Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis.Cell2021
33862619Re-evaluating Biopsy for Recurrent Glioblastoma: A Position Statement by the Christopher Davidson Forum Investigators.Neurosurgery2021
33811126Decoding Cancer Biology One Cell at a Time.Cancer Discov2021
33495604Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma.Nat Med2021
34594037Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states.Nat Genet2021
34215585A live single-cell reporter assay links intratumor heterogeneity to metastatic proclivity in Ewing sarcoma.Sci Adv2021
34087162Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma.Cancer Cell2021
32396858The Glioma Stem Cell Model in the Era of Single-Cell Genomics.Cancer Cell2020
32142659Tackling the Many Facets of Glioblastoma Heterogeneity.Cell Stem Cell2020
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Collaborators

Itay Tirosh
Weizmann Institute of Medical Sciences
Co-authored papers 20
Aviv Regev
Broad Institute of MIT and Harvard
Co-authored papers 15
Mariella G Filbin
Co-authored papers 13
Bradley E Bernstein
Broad Institute of MIT and Harvard
Co-authored papers 13
Orit Rozenblatt-Rosen
Co-authored papers 12
Michelle Monje
Co-authored papers 11
David N Louis
Co-authored papers 9
Keith L Ligon
Co-authored papers 9
McKenzie L Shaw
Co-authored papers 8
Matthew P Frosch
Massachusetts General Hospital and Harvard Medical School
Co-authored papers 6
Brian V Nahed
Harvard Medical School
Co-authored papers 5
Gaylor Boulay
Massachusetts General Hospital and Harvard Medical School
Co-authored papers 5
Esther Rheinbay
Co-authored papers 5
Todd R Golub
Broad Institute of MIT and Harvard
Co-authored papers 5
Gad Getz
Broad Institute of the Massachusetts Institute of Technology and Harvard
Co-authored papers 5
Thomas Czech
Co-authored papers 4
Johannes Gojo
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Sowmya Iyer
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Kristine Pelton
Co-authored papers 4
Angel M Carcaboso
Co-authored papers 4
Tracy T Batchelor
Brigham and Women's Hospital
Co-authored papers 4
Irene Slavc
Co-authored papers 4
Christine Haberler
Co-authored papers 4
Jaume Mora
Pediatric Cancer Center Barcelona, Hospital Sant Joan de Deu
Co-authored papers 4
Priscilla K Brastianos
Co-authored papers 4
Alex K Shalek
Institute for Medical Engineering & Science, Massachusetts Institute of Technology
Co-authored papers 4
Patrick Y Wen
Co-authored papers 3
René Geyeregger
Co-authored papers 3
Lisa Mayr
Co-authored papers 3
Liliana C Goumnerova
Co-authored papers 3
Release 1.2