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Author Details

Florian Martin
2006
91
29
Dexter Pratt (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
33220401Comparison of the biological impact of aerosol of e-vapor device with MESH® technology and cigarette smoke on human bronchial and alveolar cultures.Toxicol Lett2021
33706515<i>In Vivo</i> Profiling of a Natural Alkaloid, Anatabine, in Rodents: Pharmacokinetics and Anti-Inflammatory Efficacy.J Nat Prod2021
35295134Discriminating Spontaneous From Cigarette Smoke and THS 2.2 Aerosol Exposure-Related Proliferative Lung Lesions in A/J Mice by Using Gene Expression and Mutation Spectrum Data.Front Toxicol2021
34211495Systems Toxicology Approach for Assessing Developmental Neurotoxicity in Larval Zebrafish.Front Genet2021
32272900Lung transcriptomic clock predicts premature aging in cigarette smoke-exposed mice.BMC Genomics2020
32053266Anthropometry-based generation of personalized and population-specific human airway models.Int J Numer Method Biomed Eng2020
31975625A 6-month systems toxicology inhalation study in ApoE<sup>-/-</sup> mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke.Am J Physiol Heart Circ Physiol2020
31705857Structural, functional, and molecular impact on the cardiovascular system in ApoE<sup>-/-</sup> mice exposed to aerosol from candidate modified risk tobacco products, Carbon Heated Tobacco Product 1.2 and Tobacco Heating System 2.2, compared with cigarette smoke.Chem Biol Interact2020
33189821Ceramide ratios are affected by cigarette smoke but not heat-not-burn or e-vapor aerosols across four independent mouse studies.Life Sci2020
32638588Systems Toxicology Approach for Testing Chemical Cardiotoxicity in Larval Zebrafish.Chem Res Toxicol2020
32995294Comparing the preclinical risk profile of inhalable candidate and potential candidate modified risk tobacco products: A bridging use case.Toxicol Rep2020
33014713A meta-analysis of microRNAs expressed in human aerodigestive epithelial cultures and their role as potential biomarkers of exposure response to nicotine-containing products.Toxicol Rep2020
32780831Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice.Toxicol Sci2020
32419906Multi-omics systems toxicology study of mouse lung assessing the effects of aerosols from two heat-not-burn tobacco products and cigarette smoke.Comput Struct Biotechnol J2020
30686568Corrigendum to "The biological effects of long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product" published in Toxicology in Vitro, Volume 50, August 2018, Pages 95-108.Toxicol In Vitro2019
31903848Bridging inhaled aerosol dosimetry to physiologically based pharmacokinetic modeling for toxicological assessment: nicotine delivery systems and beyond.Crit Rev Toxicol2019
31886136Systems toxicology assessment of a representative e-liquid formulation using human primary bronchial epithelial cells.Toxicol Rep2019
31494692Application of a multi-layer systems toxicology framework for in vitro assessment of the biological effects of Classic Tobacco e-liquid and its corresponding aerosol using an e-cigarette device with MESHâ¿¢ technology.Arch Toxicol2019
31481014NPA: an R package for computing network perturbation amplitudes using gene expression data and two-layer networks.BMC Bioinformatics2019
30835057A lower impact of an acute exposure to electronic cigarette aerosols than to cigarette smoke in human organotypic buccal and small airway cultures was demonstrated using systems toxicology assessment.Intern Emerg Med2019
30828347Construction of a Suite of Computable Biological Network Models Focused on Mucociliary Clearance in the Respiratory Tract.Front Genet2019
30971916A Meta-Analysis of the Performance of a Blood-Based Exposure Response Gene Signature Across Clinical Studies on the Tobacco Heating System 2.2 (THS 2.2).Front Pharmacol2019
30763686A six-month systems toxicology inhalation/cessation study in ApoE<sup>-/-</sup> mice to investigate cardiovascular and respiratory exposure effects of modified risk tobacco products, CHTP 1.2 and THS 2.2, compared with conventional cigarettes.Food Chem Toxicol2019
30753736How complex should an in vitro model be? Evaluation of complex 3D alveolar model with transcriptomic data and computational biological network models.ALTEX2019
30873538GladiaTOX: GLobal Assessment of Dose-IndicAtor in TOXicology.Bioinformatics2019
30414959Tobacco Heating System 2.2 has a limited impact on DNA methylation of candidate enhancers in mouse lung compared with cigarette smoke.Food Chem Toxicol2019
30610935Assessment of a 72-hour repeated exposure to Swedish snus extract and total particulate matter from 3R4F cigarette smoke on gingival organotypic cultures.Food Chem Toxicol2019
29258927Quantifying the risk-reduction potential of new Modified Risk Tobacco Products.Regul Toxicol Pharmacol2018
30221212The sbv IMPROVER Systems Toxicology Computational Challenge: Identification of Human and Species-Independent Blood Response Markers as Predictors of Smoking Exposure and Cessation Status.Comput Toxicol2018
30906071Pressure-driven collective growth mechanism of planar cell colonies.J Phys D Appl Phys2018
30849254Biological changes in C57BL/6 mice following 3 weeks of inhalation exposure to cigarette smoke or e-vapor aerosols.Inhal Toxicol2018
29501877Comparative biological impacts of an aerosol from carbon-heated tobacco and smoke from cigarettes on human respiratory epithelial cultures: A systems toxicology assessment.Food Chem Toxicol2018
29524472The biological effects of long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product.Toxicol In Vitro2018
29545142A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. II. Systems toxicology assessment.Food Chem Toxicol2018
29654848A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. I. Inhalation exposure, clinical pathology and histopathology.Food Chem Toxicol2018
29505817Assessment of the impact of aerosol from a potential modified risk tobacco product compared with cigarette smoke on human organotypic oral epithelial cultures under different exposure regimens.Food Chem Toxicol2018
273886763-D nasal cultures: Systems toxicological assessment of a candidate modified-risk tobacco product.ALTEX2017
30090554Comparative effects of a candidate modified-risk tobacco product Aerosol and cigarette smoke on human organotypic small airway cultures: a systems toxicology approach.Toxicol Res (Camb)2017
30090531Systems toxicology meta-analysis of <i>in vitro</i> assessment studies: biological impact of a candidate modified-risk tobacco product aerosol compared with cigarette smoke on human organotypic cultures of the aerodigestive tract.Toxicol Res (Camb)2017
28111298Aerosol from Tobacco Heating System 2.2 has reduced impact on mouse heart gene expression compared with cigarette smoke.Food Chem Toxicol2017
28085253Crowd-Sourced Verification of Computational Methods and Data in Systems Toxicology: A Case Study with a Heat-Not-Burn Candidate Modified Risk Tobacco Product.Chem Res Toxicol2017
28882640Toxicity of the main electronic cigarette components, propylene glycol, glycerin, and nicotine, in Sprague-Dawley rats in a 90-day OECD inhalation study complemented by molecular endpoints.Food Chem Toxicol2017
28620266Mechanistic Evaluation of the Impact of Smoking and Chronic Obstructive Pulmonary Disease on the Nasal Epithelium.Clin Med Insights Circ Respir Pulm Med2017
28025120Comparative systems toxicology analysis of cigarette smoke and aerosol from a candidate modified risk tobacco product in organotypic human gingival epithelial cultures: A 3-day repeated exposure study.Food Chem Toxicol2017
27846345Systems biology for organotypic cell cultures.ALTEX2017
27865774A systems toxicology approach for comparative assessment: Biological impact of an aerosol from a candidate modified-risk tobacco product and cigarette smoke on human organotypic bronchial epithelial cultures.Toxicol In Vitro2017
27027324Effects of cigarette smoke, cessation and switching to a candidate modified risk tobacco product on the liver in Apoe -/- mice--a systems toxicology analysis.Inhal Toxicol2016
26651182In Vitro Systems Toxicology Assessment of a Candidate Modified Risk Tobacco Product Shows Reduced Toxicity Compared to That of a Conventional Cigarette.Chem Res Toxicol2016
26582801Effects of Cigarette Smoke, Cessation, and Switching to Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in C57BL/6 and Apoe-/- Mice-An Integrative Systems Toxicology Analysis.Toxicol Sci2016
26609137An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe-/- Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes.Toxicol Sci2016
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Collaborators

Philip Morris International Research Laboratories Pte. Ltd
Co-authored papers 82
Vectura Fertin Pharma
Co-authored papers 81
Universitat Basel
Co-authored papers 35
university of california los angeles
Co-authored papers 29
Johns Hopkins Bayview Medical Center
Co-authored papers 18
Philip Morris International Research Laboratories Pte. Ltd
Co-authored papers 17
FOG Pharmaceuticals Inc.
Co-authored papers 4
UC San Diego
Co-authored papers 2
Harvard Medical School
Co-authored papers 2
Co-authored papers 2
IBM T.J. Watson Research Center
Co-authored papers 1
University of Pittsburgh
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Philip Morris Research Laboratories GmbH
Co-authored papers 1
National Institute of Environmental Health Sciences
Co-authored papers 1
University of California berkeley
Co-authored papers 1
Syntimmune Inc.
Co-authored papers 1
IBM T.J. Watson Research Center
Co-authored papers 1
Co-authored papers 1
University of Trento
Co-authored papers 1
Co-authored papers 1
Institut fur Mathematik und Informatik, Universitat Greifswald
Co-authored papers 1
Friedrich Miescher Institute for Biomedical Research
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
ProtATonce Ltd, National Technical University of Athens
Co-authored papers 1
Iowa State University
Co-authored papers 1
Universite du Luxembourg
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