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Author Details
Full Name
Florian Beck
Affiliation
Max Planck Institute of Biochemistry
ORCID
Career Start Year
2005
Papers
48
H Index
29
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37613825
Towards the Visual Proteomics of C. reinhardtii using High-throughput Collaborative in situ Cryo-ET.
Microsc Microanal
2023
36122245
In situ structural analysis reveals membrane shape transitions during autophagosome formation.
Proc Natl Acad Sci U S A
2022
35346811
A feature-guided, focused 3D signal permutation method for subtomogram averaging.
J Struct Biol
2022
35811088
A transformation clustering algorithm and its application in polyribosomes structural profiling.
Nucleic Acids Res
2022
36042418
Volumetric macromolecule identification in cryo-electron tomograms using capsule networks.
BMC Bioinformatics
2022
33039147
High-resolution structure and biophysical characterization of the nucleocapsid phosphoprotein dimerization domain from the Covid-19 severe acute respiratory syndrome coronavirus 2.
Biochem Biophys Res Commun
2021
34403403
In Response.
Anesth Analg
2021
34508074
In situ cryo-electron tomography reveals gradient organization of ribosome biogenesis in intact nucleoli.
Nat Commun
2021
34089875
Cryo-EM structure of the cetacean morbillivirus nucleoprotein-RNA complex.
J Struct Biol
2021
32647264
Impaired iloprost-induced platelet inhibition and phosphoproteome changes in patients with confirmed pseudohypoparathyroidism type Ia, linked to genetic mutations in GNAS.
Sci Rep
2020
31882451
Direct visualization of degradation microcompartments at the ER membrane.
Proc Natl Acad Sci U S A
2020
30559193
Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle.
Proc Natl Acad Sci U S A
2019
31230946
The Architecture of Traveling Actin Waves Revealed by Cryo-Electron Tomography.
Structure
2019
30962530
Biogenic regions of cyanobacterial thylakoids form contact sites with the plasma membrane.
Nat Plants
2019
29398115
In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Cell
2018
30067984
Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating.
Cell Rep
2018
30301811
Combined inhibition of receptor tyrosine and p21-activated kinases as a therapeutic strategy in childhood ALL.
Blood Adv
2018
28060719
Temporal quantitative phosphoproteomics of ADP stimulation reveals novel central nodes in platelet activation and inhibition.
Blood
2017
28292943
Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome.
Mol Cell Proteomics
2017
28396430
In situ structural studies of tripeptidyl peptidase II (TPPII) reveal spatial association with proteasomes.
Proc Natl Acad Sci U S A
2017
28115689
Structural insights into the functional cycle of the ATPase module of the 26S proteasome.
Proc Natl Acad Sci U S A
2017
29229809
Proteasomes tether to two distinct sites at the nuclear pore complex.
Proc Natl Acad Sci U S A
2017
26849035
Nucleotide-dependent conformational changes of the AAA+ ATPase p97 revisited.
FEBS Lett
2016
27342858
Structure of the human 26S proteasome at a resolution of 3.9 ÿ.
Proc Natl Acad Sci U S A
2016
25613890
Proteasomes. A molecular census of 26S proteasomes in intact neurons.
Science
2015
26130806
Structural characterization of the interaction of Ubp6 with the 26S proteasome.
Proc Natl Acad Sci U S A
2015
24324209
Time-resolved characterization of cAMP/PKA-dependent signaling reveals that platelet inhibition is a concerted process involving multiple signaling pathways.
Blood
2014
24706844
Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome.
Proc Natl Acad Sci U S A
2014
23322602
Deciphering of ADP-induced, phosphotyrosine-dependent signaling networks in human platelets by Src-homology 2 region (SH2)-profiling.
Proteomics
2013
23643786
Localization of the regulatory particle subunit Sem1 in the 26S proteasome.
Biochem Biophys Res Commun
2013
23589842
Structure of the 26S proteasome with ATP-γS bound provides insights into the mechanism of nucleotide-dependent substrate translocation.
Proc Natl Acad Sci U S A
2013
23201114
Developmental changes of the protein repertoire in the rat auditory brainstem: a comparative proteomics approach in the superior olivary complex and the inferior colliculus with DIGE and iTRAQ.
J Proteomics
2013
23307401
D-score: a search engine independent MD-score.
Proteomics
2013
22215586
Localization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopy.
Proc Natl Acad Sci U S A
2012
22927375
Near-atomic resolution structural model of the yeast 26S proteasome.
Proc Natl Acad Sci U S A
2012
22665297
Robust workflow for iTRAQ-based peptide and protein quantification.
Methods Mol Biol
2012
22307589
Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach.
Proc Natl Acad Sci U S A
2012
20719249
Maximum likelihood based classification of electron tomographic data.
J Struct Biol
2011
21704708
Computer controlled cryo-electron microscopy--TOM² a software package for high-throughput applications.
J Struct Biol
2011
21298789
The good, the bad, the ugly: validating the mass spectrometric analysis of modified peptides.
Proteomics
2011
21098295
Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution.
Proc Natl Acad Sci U S A
2010
19581588
Insights into the molecular architecture of the 26S proteasome.
Proc Natl Acad Sci U S A
2009
19653995
An atomic model AAA-ATPase/20S core particle sub-complex of the 26S proteasome.
Biochem Biophys Res Commun
2009
17151018
Proteomics analysis of Thermoplasma acidophilum with a focus on protein complexes.
Mol Cell Proteomics
2007
17531228
Automated cryoelectron microscopy of "single particles" applied to the 26S proteasome.
FEBS Lett
2007
17884579
Correlative microscopy: bridging the gap between fluorescence light microscopy and cryo-electron tomography.
J Struct Biol
2007
17173858
Structural analysis of the 26S proteasome by cryoelectron tomography.
Biochem Biophys Res Commun
2007
15721576
TOM software toolbox: acquisition and analysis for electron tomography.
J Struct Biol
2005
1 - 48 of 48
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row(s) 1 - 30 of 30
Collaborators
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Max Planck Institute of Biochemistry
Co-authored papers
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Max Planck Institute of Biochemistry
Co-authored papers
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Friedrich F??rster
Utrecht University
Co-authored papers
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Max Planck Institute of Biochemistry
Co-authored papers
11
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Institute of Biochemistry, HUN-REN Biological Research Centre
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Stefan Bohn
Technical University Darmstadt
Co-authored papers
7
Andreas Schweitzer
Max Planck Institute of Biochemistry
Co-authored papers
7
Jörg Geiger
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University of California San Francisco
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Oana Mihalache
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Max-Planck Institute of Biochemistry
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McMaster University
Co-authored papers
4
Ruedi Aebersold
Institute of Molecular Systems Biology, ETH Zurich
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The Scripps Research Institute
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3
Lennart Martens
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2
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National Centre for Biotechnology (CNB CSIC), Campus Universidad Autonoma de Madrid
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2
Elizabeth Villa
University of California San Diego, USA Howard Hughes Medical Institute
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2
Thomas Walzthoeni
Institute for Computational Biology
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2
Na Sun
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