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Author Details

Pei Tang
Sichuan University
1989
155
33
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36821490Structural Elucidation of Ivermectin Binding to α7nAChR and the Induced Channel Desensitization.ACS Chem Neurosci2023
37278098Adenophorone, An Unprecedented Sesquiterpene from Eupatorium adenophorum: Structural Elucidation, Bioinspired Total Synthesis and Neuroprotective Activity Evaluation.Angew Chem Int Ed Engl2023
36632044Multi-conformers caused by conformational change of A-ring in the C<sub>18</sub>- and C<sub>19</sub>-<i>N</i>-dealkyl diterpenoid alkaloids.J Asian Nat Prod Res2023
34994369The total synthesis of <b>(-)</b>-strempeliopine <i>via</i> palladium-catalyzed decarboxylative asymmetric allylic alkylation.Chem Commun (Camb)2022
35485419Asymmetric total synthesis of prostaglandin C<sub>2</sub> TBS ether.Chem Commun (Camb)2022
36074791Catalytic asymmetric total synthesis of diazabicyclooctane β-lactamase inhibitors avibactam and relebactam.Chem Commun (Camb)2022
35312322Stereoselective Total Syntheses of C18-Oxo Eburnamine-Vincamine Alkaloids.Org Lett2022
35145092Structures of highly flexible intracellular domain of human α7 nicotinic acetylcholine receptor.Nat Commun2022
34260401Regulation and drug modulation of a voltage-gated sodium channel: Pivotal role of the S4-S5 linker in activation and slow inactivation.Proc Natl Acad Sci U S A2021
33544844Nasal Delivery of AntagomiR-741 Protects Against the Radiation-Induced Brain Injury in Mice.Radiat Res2021
34672312Stereoselective total synthesis of (±)-vindeburnol and (±)-16-<i>epi</i>-vindeburnol.Chem Commun (Camb)2021
34377422A unified strategy to prostaglandins: chemoenzymatic total synthesis of cloprostenol, bimatoprost, PGF<sub>2α</sub>, fluprostenol, and travoprost guided by biocatalytic retrosynthesis.Chem Sci2021
34076443Total Synthesis of (-)-Canadine, (-)-Rotundine, (-)-Sinactine, and (-)-Xylopinine Using a Last-Step Enantioselective Ir-Catalyzed Hydrogenation.J Org Chem2021
32191433A Thermal Place Preference Test for Discovery of Neuropathic Pain Drugs.ACS Chem Neurosci2020
31951367Functional Tolerance to Cysteine Mutations in Human α7 Nicotinic Acetylcholine Receptors.ACS Chem Neurosci2020
31880445Enantioselective Syntheses of 4<i>H</i>-3,1-Benzoxazines via Catalytic Asymmetric Chlorocyclization of <i>o</i>-Vinylanilides.J Org Chem2020
32632293Allosteric interactions in the parathyroid hormone GPCR-arrestin complex formation.Nat Chem Biol2020
32761674Enantioselective Alkynylation of Isatins: A Combination of Metal Catalysis and Organocatalysis.Chemistry2020
32978453Presence of the apolipoprotein E-ε4 allele is associated with an increased risk of sepsis progression.Sci Rep2020
32500532Enantioselective Total Syntheses of (-)-20-epi-Vincamine and (-)-20-epi-Eburnamonine by Ir-Catalyzed Asymmetric Imine Hydrogenation/Lactamization Cascade.Chemistry2020
30358011mDia1 and Cdc42 Regulate Activin B-Induced Migration of Bone Marrow-Derived Mesenchymal Stromal Cells.Stem Cells2019
31707205Intranasal Administration of miR-146a Agomir Rescued the Pathological Process and Cognitive Impairment in an AD Mouse Model.Mol Ther Nucleic Acids2019
31387910A Functional Polymorphism-Mediated Disruption of EGR1/ADAM10 Pathway Confers the Risk of Sepsis Progression.mBio2019
31214610Rs2015 Polymorphism in miRNA Target Site of Sirtuin2 Gene Is Associated with the Risk of Parkinson's Disease in Chinese Han Population.Biomed Res Int2019
31525026<sup>19</sup>F Paramagnetic Relaxation-Based NMR for Quaternary Structural Restraints of Ion Channels.ACS Chem Biol2019
31447838IL-36β Promotes CD8<sup>+</sup> T Cell Activation and Antitumor Immune Responses by Activating mTORC1.Front Immunol2019
31150831The molecular determinants of neurosteroid binding in the GABA(A) receptor.J Steroid Biochem Mol Biol2019
30938934Nanotechnology-Mediated Drug Delivery for the Treatment of Obesity and Its Related Comorbidities.Adv Healthc Mater2019
30781441Activin B Stimulates Mouse Vibrissae Growth and Regulates Cell Proliferation and Cell Cycle Progression of Hair Matrix Cells through ERK Signaling.Int J Mol Sci2019
30511419GRK5 influences the phosphorylation of tau via GSK3β and contributes to Alzheimer's disease.J Cell Physiol2019
29684584Deletion of epithelial cell-specific Cdc42 leads to enamel hypermaturation in a conditional knockout mouse model.Biochim Biophys Acta Mol Basis Dis2018
30018039Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites.J Gen Physiol2018
30091930Enantioselective Synthesis of ABCF Tetracyclic Framework of Daphniphyllum Alkaloid Calyciphylline N.Org Lett2018
29896429Invasion of Peripheral Immune Cells into Brain Parenchyma after Cardiac Arrest and Resuscitation.Aging Dis2018
29869798iKA-CRISPR hESCs for inducible and multiplex orthogonal gene knockout and activation.FEBS Lett2018
30266951Structural basis of neurosteroid anesthetic action on GABA<sub>A</sub> receptors.Nat Commun2018
30562735miR-486-3p Influences the Neurotoxicity of a-Synuclein by Targeting the SIRT2 Gene and the Polymorphisms at Target Sites Contributing to Parkinson's Disease.Cell Physiol Biochem2018
29673534Solution NMR Studies of Anesthetic Interactions with Ion Channels.Methods Enzymol2018
29673527X-Ray Crystallographic Studies for Revealing Binding Sites of General Anesthetics in Pentameric Ligand-Gated Ion Channels.Methods Enzymol2018
29445451Recent progress on the molecular pharmacology of propofol.F1000Res2018
27916519Structural Basis of Alcohol Inhibition of the Pentameric Ligand-Gated Ion Channel ELIC.Structure2017
28338268Chiral Amino Alcohol Accelerated and Stereocontrolled Allylboration of Iminoisatins: Highly Efficient Construction of Adjacent Quaternary Stereogenic Centers.Angew Chem Int Ed Engl2017
28295910Analysis of Nitroxide-Based Distance Measurements in Cell Extracts and in Cells by Pulsed ESR Spectroscopy.Chemphyschem2017
28793215Ketamine Inhibition of the Pentameric Ligand-Gated Ion Channel GLIC.Biophys J2017
27693126RhoA regulates Activin B-induced stress fiber formation and migration of bone marrow-derived mesenchymal stromal cell through distinct signaling.Biochim Biophys Acta Gen Subj2017
26809892Graphene Oxide Catalyzed C-H Bond Activation: The Importance of Oxygen Functional Groups for Biaryl Construction.Angew Chem Int Ed Engl2016
26650028Formal Synthesis of Anticoagulant Drug Fondaparinux Sodium.J Org Chem2016
27628686Effects of Propofol General Anesthesia on Olfactory Relearning.Sci Rep2016
27856739Fluorine-19 NMR and computational quantification of isoflurane binding to the voltage-gated sodium channel NaChBac.Proc Natl Acad Sci U S A2016
27385587Functional Human α7 Nicotinic Acetylcholine Receptor (nAChR) Generated from Escherichia coli.J Biol Chem2016
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Collaborators

Nanjing Drum Tower Hospital
Co-authored papers 94
University of Pennsylvania, Perelman School of Medicine
Co-authored papers 9
Co-authored papers 2
Jiangnan University
Co-authored papers 2
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University of California San Francisco
Co-authored papers 1
University of Illinois
Co-authored papers 1
and Center for Structural Biology, Vanderbilt University
Co-authored papers 1
Technische Universitat Munchen (TUM)
Co-authored papers 1
University of Bristol
Co-authored papers 1
The University of Manchester
Co-authored papers 1
Rutgers University
Co-authored papers 1
Center for Integrated Protein Science, Technische Universitat Munchen
Co-authored papers 1
Leicester Institute of Structural and Chemical Biology, University of Leicester
Co-authored papers 1
University of Texas Southwestern Medical Center
Co-authored papers 1
The University of Sheffield
Co-authored papers 1
Institute of Systems, The University of Liverpool
Co-authored papers 1
Institute of Integrative Biology, University of Liverpool
Co-authored papers 1
Columbia University
Co-authored papers 1
National Institutes of Health
Co-authored papers 1
Zernike Institute for Advanced Materials, University of Groningen
Co-authored papers 1
Co-authored papers 1
University of Oxford
Co-authored papers 1
Co-authored papers 1
The Medical Research Council Biomedical NMR Centre, The Francis Crick Institute
Co-authored papers 1
University of Cambridge
Co-authored papers 1
Carnegie Mellon University
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Imperial College London
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Carnegie Mellon University
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Institute for Protein Research, Osaka University
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