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Author Details

Moutih Rafei
Universite de Montreal
2007
50
19
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37776054Intratumoral administration of unconjugated Accumâ¿¢ impairs the growth of pre-established solid lymphoma tumors.Cancer Sci2023
35203247Humoral Immunity to Allogeneic Immunoproteasome-Expressing Mesenchymal Stromal Cells Requires Efferocytosis by Endogenous Phagocytes.Cells2022
35795568Recent Advances in Cancer Drug Discovery Through the Use of Phenotypic Reporter Systems, Connectivity Mapping, and Pooled CRISPR Screening.Front Pharmacol2022
35492876Promoting antigen escape from dendritic cell endosomes potentiates anti-tumoral immunity.Cell Rep Med2022
35744930Accumâ¿¢ Technology: A Novel Conjugable Primer for Onco-Immunotherapy.Molecules2022
35681511LSD1 Inhibition Enhances the Immunogenicity of Mesenchymal Stromal Cells by Eliciting a dsRNA Stress Response.Cells2022
35848838Teasing Out the Interplay Between Natural Killer Cells and Nociceptor Neurons.J Vis Exp2022
36437872The <i>CIt</i> protocol: A blueprint to potentiate the immunogenicity of immunoproteasome-reprogrammed mesenchymal stromal cells.iScience2022
35892560CD146 Defines a Mesenchymal Stromal Cell Subpopulation with Enhanced Suppressive Properties.Cells2022
36323780Nociceptor neurons affect cancer immunosurveillance.Nature2022
35012668UM171A-induced ROS promote antigen cross-presentation of immunogenic peptides by bone marrow-derived mesenchymal stromal cells.Stem Cell Res Ther2022
34980045Bone marrow aspirate concentrate versus platelet-rich plasma for treating knee osteoarthritis: a one-year non-randomized retrospective comparative study.BMC Musculoskelet Disord2022
33453289FcεR1-expressing nociceptors trigger allergic airway inflammation.J Allergy Clin Immunol2021
33542714Thymoproteasome-Expressing Mesenchymal Stromal Cells Confer Protective Anti-Tumor Immunity <i>via</i> Cross-Priming of Endogenous Dendritic Cells.Front Immunol2021
33816523Autologous BMAC Therapy Improves Spinal Degenerative Joint Disease in Lower Back Pain Patients.Front Med (Lausanne)2021
34881261Cell Therapy: Types, Regulation, and Clinical Benefits.Front Med (Lausanne)2021
35028603Engineering immunoproteasome-expressing mesenchymal stromal cells: A potent cellular vaccine for lymphoma and melanoma in mice.Cell Rep Med2021
33087510TACIMA-218: A Novel Pro-Oxidant Agent Exhibiting Selective Antitumoral Activity.Mol Cancer Ther2021
32133358Mesenchymal Stem Cells Beyond Regenerative Medicine.Front Cell Dev Biol2020
33103068Integrative Transcriptome Analyses Empower the Anti-COVID-19 Drug Arsenal.iScience2020
32231565A Novel Sulfonyl-Based Small Molecule Exhibiting Anti-cancer Properties.Front Pharmacol2020
31108430Restoring thymic function: Then and now.Cytokine2019
31552057Cardiotrophin-Like Cytokine Factor 1 Exhibits a Myeloid-Biased Hematopoietic-Stimulating Function.Front Immunol2019
31196146Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation.J Exp Clin Cancer Res2019
28615039Interleukin-21 promotes thymopoiesis recovery following hematopoietic stem cell transplantation.J Hematol Oncol2017
28362377A Fluorescence-based Lymphocyte Assay Suitable for High-throughput Screening of Small Molecules.J Vis Exp2017
26762709Interleukin-21 administration to aged mice rejuvenates their peripheral T-cell pool by triggering de novo thymopoiesis.Aging Cell2016
26748727Therapeutic utility of the newly discovered properties of interleukin-21.Cytokine2016
25015277Ex vivo generation of murine IL-10-producing B cells by fusokines.Methods Mol Biol2014
25312642Inflammatory monocytes promote progression of Duchenne muscular dystrophy and can be therapeutically targeted via CCR2.EMBO Mol Med2014
23043071Differential effects of γc cytokines on postselection differentiation of CD8 thymocytes.Blood2013
24023776Interleukin-21 accelerates thymic recovery from glucocorticoïd-induced atrophy.PLoS One2013
22760541Inducible IL10(+) suppressor B cells inhibit CNS inflammation and T helper 17 polarization.Mol Ther2012
21943176A MCP1 fusokine with CCR2-specific tumoricidal activity.Mol Cancer2011
21844388Development and function of innate polyclonal TCRalphabeta+ CD8+ thymocytes.J Immunol2011
20389285A fusion of GMCSF and IL-21 initiates hypersignaling through the IL-21Ralpha chain with immune activating and tumoricidal effects in vivo.Mol Ther2010
21083526A CCL2-based fusokine as a novel biopharmaceutical for the treatment of CCR2-driven autoimmune diseases.Crit Rev Immunol2010
21076067A dendritic cell population generated by a fusion of GM-CSF and IL-21 induces tumor-antigen-specific immunity.J Immunol2010
20188040[A chimeric cytokine to help autoimmune diseases].Med Sci (Paris)2010
19234156Selective inhibition of CCR2 expressing lymphomyeloid cells in experimental autoimmune encephalomyelitis by a GM-CSF-MCP1 fusokine.J Immunol2009
20635907GIFT15 fusokine to foil immunity's follies.Immunotherapy2009
19592643An engineered GM-CSF-CCL2 fusokine is a potent inhibitor of CCR2-driven inflammation as demonstrated in a murine model of inflammatory arthritis.J Immunol2009
19587377Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome.Blood2009
19602999Allogeneic mesenchymal stem cells for treatment of experimental autoimmune encephalomyelitis.Mol Ther2009
19668193A granulocyte-macrophage colony-stimulating factor and interleukin-15 fusokine induces a regulatory B cell population with immune suppressive properties.Nat Med2009
19367255Autologous bone marrow stromal cells genetically engineered to secrete an igf-I receptor decoy prevent the growth of liver metastases.Mol Ther2009
19414750Mesenchymal stromal cells ameliorate experimental autoimmune encephalomyelitis by inhibiting CD4 Th17 T cells in a CC chemokine ligand 2-dependent manner.J Immunol2009
19088705Mesenchymal stromal cells engineered to express erythropoietin induce anti-erythropoietin antibodies and anemia in allorecipients.Mol Ther2009
18812467Mesenchymal stromal cell-derived CCL2 suppresses plasma cell immunoglobulin production via STAT3 inactivation and PAX5 induction.Blood2008
17082320A GMCSF and IL-15 fusokine leads to paradoxical immunosuppression in vivo via asymmetrical JAK/STAT signaling through the IL-15 receptor complex.Blood2007
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Collaborators

Nehme El-Hachem
Centre Hospitalier Universitaire Sainte-Justine Research Centre
Co-authored papers 11
Alexandre Rouette
Charles-Bruneau Cancer Center, Centre Hospitalier Universitaire (CHU) Sainte-Justine
Co-authored papers 2
Annie Beaudry
Sainte-Justine University Hospital Research Center
Co-authored papers 2
No??l J-M Raynal
Sainte-Justine University Hospital Research Center
Co-authored papers 2
Lawrence H Boise
Winship Cancer Institute, Emory University
Co-authored papers 1
Michael Downey
Ottawa Institute of Systems Biology, University of Ottawa
Co-authored papers 1
Kolja Eppert
McGill University
Co-authored papers 1
Ema Flores-D??az
Institute of Research in Immunology and Cancer, Universite de Montreal
Co-authored papers 1
Chantal Richer
CHU Sainte-Justine Research Center
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Gabrielle McInnes
Departement de pharmacologie et physiologie, Universite de Montreal
Co-authored papers 1
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 1
Daniel Sinnett
Sainte-Justine University Hospital Research Center
Co-authored papers 1
Gregory Armaos
Departement de pharmacologie et physiologie, Universite de Montreal
Co-authored papers 1
Ronny Drapkin
University of Pennsylvania School of Medicine
Co-authored papers 1
Michel L Tremblay
Co-authored papers 1
Maxime Caron
Centre Hospitalier Universitaire Sainte-Justine
Co-authored papers 1
Karen M Doody
Co-authored papers 1
Trang Hoang
Department of Biomedical Science and Center for Bio-Nanomaterials, Daegu University
Co-authored papers 1
Elodie M Da Costa
Departement de pharmacologie et physiologie, Universite de Montreal
Co-authored papers 1
Benjamin Haibe-Kains
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Christian Beaus??jour
CHU Sainte-Justine Research Center
Co-authored papers 1
Serge McGraw
Centre Hospitalier Universitaire Sainte-Justine Research Center
Co-authored papers 1
Andr?? Haman
Universite de Montreal, Institute for Research in Immunology and Cancer
Co-authored papers 1
Ga??l Moquin-Beaudry
Universite de Montreal
Co-authored papers 1
Pascal St-Onge
CHU Sainte-Justine Research Center
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Yuka Sai
Department of Cellular and Molecular Medicine and Ottawa Institute of Systems Biology
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Meaghan Boileau
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Mukut Sharma
Midwest Veterans' Biomedical Research Foundation, KCVA Medical Center
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Virginie Bertrand-Lehouillier
Sainte-Justine University Hospital Research Center (7.17.)
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Release 1.2