Author details

Full Name

Peter N Devreotes

Affiliation

ORCID

Career Start Year

1975

Papers

239

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37220748	Actuation of single downstream nodes in growth factor network steers immune cell migration.		2023
37664034	The effects of statins in patients with advanced-stage cancers -Â a systematic review and meta-analysis.		2023
37693515	Ras-mediated homeostatic control of front-back signaling dictates cell polarity.		2023
36712016	A dynamic partitioning mechanism polarizes membrane protein distribution.		2023
37492221	Optogenetic modulation of guanine nucleotide exchange factors of Ras superfamily proteins directly controls cell shape and movement.		2023
35318938	Cortical waves mediate the cellular response to electric fields.	eLife	2022
36202973	Spatiotemporal dynamics of membrane surface charge regulates cell polarity and migration.	Nature Cell Biology	2022
34898015	Coupling traction force patterns and actomyosin wave dynamics reveals mechanics of cell motion.	Molecular Systems Biology	2021
34127068	Electric signals counterbalanced posterior vs anterior PTEN signaling in directed migration of Dictyostelium.	Cell and Bioscience	2021
34289909	Correction to: Electric signals counterbalanced posterior vs anterior PTEN signaling in directed migration of Dictyostelium.	Cell and Bioscience	2021
33586225	Reverse fountain flow of phosphatidylinositol-3,4-bisphosphate polarizes migrating cells.	EMBO Journal	2021
34260581	Three-dimensional stochastic simulation of chemoattractant-mediated excitability in cells.	PLoS Computational Biology	2021
33657369	Hedgehog signaling and Tre1 regulate actin dynamics through PI(4,5)P to direct migration of Drosophila embryonic germ cells.	Cell Reports	2021
34676215	Using Live-Cell Imaging and Synthetic Biology to Probe Directed Migration in .	Frontiers in Cell and Developmental Biology	2021
32877650	An Excitable Ras/PI3K/ERK Signaling Network Controls Migration and Oncogenic Transformation in Epithelial Cells.	Developmental Cell	2020
31836289	Excitable networks controlling cell migration during development and disease.	Seminars in Cell and Developmental Biology	2020
32051246	Statin-induced GGPP depletion blocks macropinocytosis and starves cells with oncogenic defects.	Proceedings of the National Academy of Sciences of the United States of America	2020
32821814	Traveling and standing waves mediate pattern formation in cellular protrusions.	Science advances	2020
30858181	Wave patterns organize cellular protrusions and control cortical dynamics.	Molecular Systems Biology	2019
31847757	A minimal computational model for three-dimensional cell migration.	J R Soc Interface	2019
31840779	The excitable signal transduction networks: movers and shapers of eukaryotic cell migration.		2019
31671039	Moving toward molecular mechanisms for chemotaxis in eukaryotic cells.	Molecular Biology of the Cell	2019
31221628	Cell migration directionality and speed are independently regulated by RasG and GÎ² in cells in electrotaxis.	Biology Open	2019
29634937	Coordination of Receptor Tyrosine Kinase Signaling and Interfacial Tension Dynamics Drives Radial Intercalation and Tube Elongation.	Dev Cell	2018
30454895	Chemoattractant receptors activate, recruit and capture G proteins for wide range chemotaxis.	Biochemical and Biophysical Research Communications	2018
30194235	Mutually inhibitory Ras-PI(3,4)P feedback loops mediate cell migration.	Proceedings of the National Academy of Sciences of the United States of America	2018
29602807	Insight from the maximal activation of the signal transduction excitable network in .	Proceedings of the National Academy of Sciences of the United States of America	2018
29155792	Assessment of Dictyostelium discoideum Response to Acute Mechanical Stimulation.	Journal of Visualized Experiments	2017
28346441	Altering the threshold of an excitable signal transduction network changes cell migratory modes.	Nature Cell Biology	2017
28679472	NKCC1 Regulates Migration Ability of Glioblastoma Cells by Modulation of Actin Dynamics and Interacting with Cofilin.	eBioMedicine	2017
28847951	Shear force-based genetic screen reveals negative regulators of cell adhesion and protrusive activity.	Proceedings of the National Academy of Sciences of the United States of America	2017
28793794	Excitable Signal Transduction Networks in Directed Cell Migration.	Annual Review of Cell and Developmental Biology	2017
28475870	A Tunable Brake for HECT Ubiquitin Ligases.	Mol Cell	2017
27821730	Chemical and mechanical stimuli act on common signal transduction and cytoskeletal networks.	Proceedings of the National Academy of Sciences of the United States of America	2016
26890004	GÎ² Regulates Coupling between Actin Oscillators for Cell Polarity and Directional Migration.	PLoS Biology	2016
26144553	The GATA transcription factor GtaC regulates early developmental gene expression dynamics in Dictyostelium.	Nature Communications	2015
25448479	Engineering PTEN function: membrane association and activity.	Methods	2015
25263454	A new class of cancer-associated PTEN mutations defined by membrane translocation defects.	Oncogene	2015
26012633	A large-scale screen reveals genes that mediate electrotaxis in Dictyostelium discoideum.	Science Signaling	2015
26216063	Opening the conformation is a master switch for the dual localization and phosphatase activity of PTEN.	Scientific Reports	2015
26130809	Novel protein Callipygian defines the back of migrating cells.	Proceedings of the National Academy of Sciences of the United States of America	2015
26238352	Signaling networks that regulate cell migration.	Cold Spring Harb Perspect Biol	2015
24653039	Nucleocytoplasmic shuttling of a GATA transcription factor functions as a development timer.	Science	2014
25437564	The directional response of chemotactic cells depends on a balance between cytoskeletal architecture and the external gradient.	Cell Reports	2014
25346418	Evolutionarily conserved coupling of adaptive and excitable networks mediates eukaryotic chemotaxis.	Nature Communications	2014
24292679	Mechanism of human PTEN localization revealed by heterologous expression in Dictyostelium.	Oncogene	2014
24985344	A unified nomenclature and amino acid numbering for human PTEN.	Sci Signal	2014
24979808	Engineering ePTEN, an enhanced PTEN with increased tumor suppressor activities.	Proc Natl Acad Sci U S A	2014
24846395	Moving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytes.	Cellular and Molecular Life Sciences	2014
23370390	Hippo on the move: tumor suppressor regulates adhesion and migration.	Cell Cycle	2013