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Author Details

Thomas H Hampton
Geisel School of Medicine, Dartmouth College
2007
68
28
PMIDPaper TitleJournal TitlePublished Year
36661299Community composition shapes microbial-specific phenotypes in a cystic fibrosis polymicrobial model system.Elife2023
37491532Comparative effects of CFTR modulators on phagocytic, metabolic and inflammatory profiles of CF and nonCF macrophages.Sci Rep2023
37662412Analysis of <i>Pseudomonas aeruginosa</i> transcription in an <i>ex vivo</i> cystic fibrosis sputum model identifies metal restriction as a gene expression stimulus.bioRxiv2023
37577487An In Vitro Medium for Modeling Gut Dysbiosis Associated with Cystic Fibrosis.bioRxiv2023
37975659Rocket-miR, a translational launchpad for miRNA-based antimicrobial drug development.mSystems2023
37256658An rRNA fragment in extracellular vesicles secreted by human airway epithelial cells increases the fluoroquinolone sensitivity of <i>P. aeruginosa</i>.Am J Physiol Lung Cell Mol Physiol2023
37287312PlmCas12e (CasX2) cleavage of CCR5: impact of guide RNA spacer length and PAM sequence on cleavage activity.RNA Biol2023
37404016Development of the intestinal microbiome in cystic fibrosis in early life.mSphere2023
36711562CAS12e (CASX2) CLEAVAGE OF CCR5: IMPACT OF GUIDE RNA LENGTH AND PAM SEQUENCE ON CLEAVAGE ACTIVITY.bioRxiv2023
36183834Tryptophan mutations in G3BP1 tune the stability of a cellular signaling hub by weakening transient interactions with Caprin1 and USP10.J Biol Chem2022
35710652CF-Seq, an accessible web application for rapid re-analysis of cystic fibrosis pathogen RNA sequencing studies.Sci Data2022
36259735ESKAPE Act Plus: Pathway Activation Analysis for Bacterial Pathogens.mSystems2022
33471607CF monocyte-derived macrophages have an attenuated response to extracellular vesicles secreted by airway epithelial cells.Am J Physiol Lung Cell Mol Physiol2021
33795318Healthy versus inflamed lung environments differentially affect mesenchymal stromal cells.Eur Respir J2021
33758032GAUGE-Annotated Microbial Transcriptomic Data Facilitate Parallel Mining and High-Throughput Reanalysis To Form Data-Driven Hypotheses.mSystems2021
33727344One versus Many: Polymicrobial Communities and the Cystic Fibrosis Airway.mBio2021
34579569The Burkholderia cenocepacia Type VI Secretion System Effector TecA Is a Virulence Factor in Mouse Models of Lung Infection.mBio2021
34544277Model Systems to Study the Chronic, Polymicrobial Infections in Cystic Fibrosis: Current Approaches and Exploring Future Directions.mBio2021
34260396Let-7b-5p in vesicles secreted by human airway cells reduces biofilm formation and increases antibiotic sensitivity of <i>P. aeruginosa</i>.Proc Natl Acad Sci U S A2021
34232099Mild Cystic Fibrosis Lung Disease Is Associated with Bacterial Community Stability.Microbiol Spectr2021
32289118Specificity in PDZ-peptide interaction networks: Computational analysis and review.J Struct Biol X2020
31685535Availability of Zinc Impacts Interactions between Streptococcus sanguinis and Pseudomonas aeruginosa in Coculture.J Bacteriol2020
31980538<i>Pseudomonas aeruginosa lasR</i> mutant fitness in microoxia is supported by an Anr-regulated oxygen-binding hemerythrin.Proc Natl Acad Sci U S A2020
32901521Differential effects of the cystic fibrosis lung inflammatory environment on mesenchymal stromal cells.Am J Physiol Lung Cell Mol Physiol2020
32616918Altered iron metabolism in cystic fibrosis macrophages: the impact of CFTR modulators and implications for Pseudomonas aeruginosa survival.Sci Rep2020
32668165SARS-CoV-2 (COVID-19) and cystic fibrosis.Am J Physiol Lung Cell Mol Physiol2020
32521165Selection of reference genes for quantitative PCR: identifying reference genes for airway epithelial cells exposed to <i>Pseudomonas aeruginosa</i>.Am J Physiol Lung Cell Mol Physiol2020
32238195Lung function and microbiota diversity in cystic fibrosis.Microbiome2020
32514536Single-cell RNA-seq Analysis Reveals That Prenatal Arsenic Exposure Results in Long-term, Adverse Effects on Immune Gene Expression in Response to Influenza A Infection.Toxicol Sci2020
30476744Profiling microRNA expression in Atlantic killifish (Fundulus heteroclitus) gill and responses to arsenic and hyperosmotic stress.Aquat Toxicol2019
31270372Functional and metabolic impairment in cigarette smoke-exposed macrophages is tied to oxidative stress.Sci Rep2019
29146575Lumacaftor (VX-809) restores the ability of CF macrophages to phagocytose and kill Pseudomonas aeruginosa.Am J Physiol Lung Cell Mol Physiol2018
29979584Arsenic Reduces Gene Expression Response to Changing Salinity in Killifish.Environ Sci Technol2018
28982736An epoxide hydrolase secreted by Pseudomonas aeruginosa decreases mucociliary transport and hinders bacterial clearance from the lung.Am J Physiol Lung Cell Mol Physiol2018
27942839Immune modulation associated with vascular endothelial growth factor (VEGF) blockade in patients with glioblastoma.Cancer Immunol Immunother2017
28201664The landscape of extreme genomic variation in the highly adaptable Atlantic killifish.Genome Biol Evol2017
29036513ScanGEO: parallel mining of high-throughput gene expression data.Bioinformatics2017
28719869Effectiveness of table top water pitcher filters to remove arsenic from drinking water.Environ Res2017
27980032Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators.Proc Natl Acad Sci U S A2017
26974965The mitogen-activated protein kinase pathway plays a critical role in regulating immunological properties of BRAF mutant cutaneous melanoma cells.Melanoma Res2016
27481238Use of a Multiplex Transcript Method for Analysis of Pseudomonas aeruginosa Gene Expression Profiles in the Cystic Fibrosis Lung.Infect Immun2016
27295279A Novel Mechanism of Host-Pathogen Interaction through sRNA in Bacterial Outer Membrane Vesicles.PLoS Pathog2016
26943329Analysis of Lung Microbiota in Bronchoalveolar Lavage, Protected Brush and Sputum Samples from Subjects with Mild-To-Moderate Cystic Fibrosis Lung Disease.PLoS One2016
25618892Regulatory T cells are not a strong predictor of survival for patients with glioblastoma.Neuro Oncol2015
24332997Iron supplementation does not worsen respiratory health or alter the sputum microbiome in cystic fibrosis.J Cyst Fibros2014
25408892Characterization and quantification of the fungal microbiome in serial samples from individuals with cystic fibrosis.Microbiome2014
25068658The microbiota regulates susceptibility to Fas-mediated acute hepatic injury.Lab Invest2014
25071935The microbiome in pediatric cystic fibrosis patients: the role of shared environment suggests a window of intervention.Microbiome2014
25097758Letter to the editor.J Immunother Cancer2014
25158801Natural selection canalizes expression variation of environmentally induced plasticity-enabling genes.Mol Biol Evol2014
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Collaborators

Dartmouth College
Co-authored papers 30
Geisel School of Medicine at Dartmouth
Co-authored papers 18
Geisel School of Medicine at Dartmouth
Co-authored papers 16
Co-authored papers 8
University of Virginia Health System
Co-authored papers 8
Geisel School of Medicine at Dartmouth
Co-authored papers 5
University of Birmingham
Co-authored papers 4
Dartmouth Health and the Dartmouth Cancer Center, USA Geisel School of Medicine
Co-authored papers 3
Massachusetts Institute of Technology
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
North Carolina State University
Co-authored papers 2
University of Pennsylvania
Co-authored papers 2
University of California san francisco
Co-authored papers 2
Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth
Co-authored papers 2
Dartmouth College Geisel School of Medicine, Princeton University, University of Colorado Anschutz Medical Campus, University of Pennsylvania Perelman School of Medicine
Co-authored papers 2
Geisel School of Medicine at Dartmouth
Co-authored papers 2
Cardiovascular Research Institute, University of California san francisco
Co-authored papers 2
Oregon State University
Co-authored papers 2
Geisel School of Medicine at Dartmouth
Co-authored papers 1
Indiana University
Co-authored papers 1
Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center
Co-authored papers 1
Dartmouth Hitchcock Medical Center
Co-authored papers 1
University of Idaho
Co-authored papers 1
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
Geisel School of Medicine at Dartmouth
Co-authored papers 1
Co-authored papers 1
Dartmouth College
Co-authored papers 1
Woods Hole Oceanographic Institution
Co-authored papers 1
Geisel School of Medicine at Dartmouth
Co-authored papers 1