Author details

Full Name

Suthesh Sivapalaratnam

Affiliation

ORCID

Career Start Year

2010

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37292725	Increased bleeding and thrombosis in myeloproliferative neoplasms mediated through altered expression of inherited platelet disorder genes.		2023
38066923	Diagnosis and laboratory monitoring of hemophilia A.		2023
34970735	Vaccine-induced immune thrombocytopenia and thrombosis: The decline in anti-platelet factor 4 antibodies is assay-dependent.	British Journal of Haematology	2022
32736772	An overview of thrombotic complications of old and new anticancer drugs.	Thrombosis Research	2020
32369280	Lupus Anticoagulant and Abnormal Coagulation Tests in Patients with Covid-19.	New England Journal of Medicine	2020
32693407	Novel manifestations of immune dysregulation and granule defects in gray platelet syndrome.	Blood	2020
31441040	A novel variant causing Î±2 antiplasmin deficiency: case report and experience in a UK centre.	British Journal of Haematology	2019
30545925	High-throughput elucidation of thrombus formation reveals sources of platelet function variability.	Haematologica	2019
31217188	Germline mutations in the transcription factor IKZF5 cause thrombocytopenia.	Blood	2019
30729496	Artificial intelligence and machine learning in haematology.	British Journal of Haematology	2019
31160809	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2019
31064749	Diagnostic high-throughput sequencing of 2396 patients with bleeding, thrombotic, and platelet disorders.	Blood	2019
31368112	Treatment of post-transfusion hyperhaemolysis syndrome in Sickle Cell Disease with the anti-IL6R humanised monoclonal antibody Tocilizumab.	British Journal of Haematology	2019
31307835	Coagulation and anticoagulation in the intraoperative setting.	Transfusion and Apheresis Science	2019
29273807	Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
29999440	Disseminated intravascular coagulation: an update on pathogenesis and diagnosis.	Expert Review of Hematology	2018
29549330	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
29549329	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
28146470	Rare and low-frequency coding variants alter human adult height.	Nature	2017
28770004	Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals.	BioData Min	2017
28612396	Diagnosis of inherited bleeding disorders in the genomic era.	British Journal of Haematology	2017
29083408	Exome-wide association study of plasma lipids in >300,000 individuals.	Nat Genet	2017
28064200	Rare variants in GP1BB are responsible for autosomal dominant macrothrombocytopenia.	Blood	2017
27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Cell	2016
25898923	A rare variant in MCF2L identified using exclusion linkage in a pedigree with premature atherosclerosis.	Eur J Hum Genet	2016
27045730	A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol lowering.	Pharmacogenomics	2016
27084890	A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders.	Blood	2016
25979724	Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis.	Int J Epidemiol	2016
27684604	Genetic analysis of emerging risk factors in coronary artery disease.	Atherosclerosis	2016
24474739	Mendelian randomization of blood lipids for coronary heart disease.	Eur Heart J	2015
25537442	Hemostatic abnormalities in critically ill patients.		2015
25487149	Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction.	Nature	2015
24780546	Abnormal hemostatic parameters in patients with myocardial infarction but angiographically normal coronary arteries.	International Journal of Cardiology	2014
24457431	Breast cancer genetics: the past, present and future.		2014
24219970	Common genetic variants do not associate with CAD in familial hypercholesterolemia.	Eur J Hum Genet	2014
24509480	Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.	Nat Genet	2014
24879339	Mutation in KERA identified by linkage analysis and targeted resequencing in a pedigree with premature atherosclerosis.	PLoS One	2014
23243195	The impact of partial and complete loss-of-function mutations in endothelial lipase on high-density lipoprotein levels and functionality in humans.	Circ Cardiovasc Genet	2013
22968135	Low-density lipoprotein receptor mutations generate synthetic genome-wide associations.	Eur J Hum Genet	2013
24072694	Exome sequencing and directed clinical phenotyping diagnose cholesterol ester storage disease presenting as autosomal recessive hypercholesterolemia.	Arterioscler Thromb Vasc Biol	2013
23739627	Monocyte gene expression and coronary artery disease.		2013
23236364	Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations.	PLoS One	2012
22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Nat Genet	2012
22421169	Asymptomatic individuals with a positive family history for premature coronary artery disease and elevated coronary calcium scores benefit from statin treatment: a post hoc analysis from the St. Francis Heart Study.	JACC: Cardiovascular Imaging	2012
22363809	Monocyte gene expression signature of patients with early onset coronary artery disease.	PLoS One	2012
23063622	Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.	Am J Hum Genet	2012
21738486	Maps of open chromatin guide the functional follow-up of genome-wide association signals: application to hematological traits.	PLoS Genet	2011
21378990	Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.	Nat Genet	2011
21369780	Genome-wide association studies in atherosclerosis.	Current Atherosclerosis Reports	2011
22022480	Platelets in patients with premature coronary artery disease exhibit upregulation of miRNA340* and miRNA624*.	PLoS ONE	2011