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Author Details

Mohammad A Mandegar
Gladstone Institute of Cardiovascular Disease
2006
24
16
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35857625Phenotypic screening with deep learning identifies HDAC6 inhibitors as cardioprotective in a BAG3 mouse model of dilated cardiomyopathy.Sci Transl Med2022
34338636Deep learning detects cardiotoxicity in a high-content screen with induced pluripotent stem cell-derived cardiomyocytes.Elife2021
32497296Advancing physiological maturation in human induced pluripotent stem cell-derived cardiac muscle by gene editing an inducible adult troponin isoform switch.Stem Cells2020
32629158Quantifying drug-induced structural toxicity in hepatocytes and cardiomyocytes derived from hiPSCs using a deep learning method.J Pharmacol Toxicol Methods2020
30389344MESP1 knock-down in human iPSC attenuates early vascular progenitor cell differentiation after completed primitive streak specification.Dev Biol2019
30298816Spatiotemporal mosaic self-patterning of pluripotent stem cells using CRISPR interference.Elife2018
30244869Esophageal Organoids from Human Pluripotent Stem Cells Delineate Sox2 Functions during Esophageal Specification.Cell Stem Cell2018
31015724Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload.Nat Biomed Eng2018
27869805Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system.Nat Med2017
28400398Multi-Imaging Method to Assay the Contractile Mechanical Output of Micropatterned Human iPSC-Derived Cardiac Myocytes.Circ Res2017
28724793A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress.JCI Insight2017
27980086CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells.Science2017
26724721Efficient CRISPR/Cas9-Based Genome Engineering in Human Pluripotent Stem Cells.Curr Protoc Hum Genet2016
27095412Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses.Sci Rep2016
26971820CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs.Cell Stem Cell2016
25333967Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales.Tissue Eng Part C Methods2015
25748532Human iPSC-based cardiac microphysiological system for drug screening applications.Sci Rep2015
25801505A non-invasive platform for functional characterization of stem-cell-derived cardiomyocytes with applications in cardiotoxicity testing.Stem Cell Reports2015
21159002Haploids adapt faster than diploids across a range of environments.J Evol Biol2011
21593218Functional human artificial chromosomes are generated and stably maintained in human embryonic stem cells.Hum Mol Genet2011
21188651An improved technique for chromosomal analysis of human ES and iPS cells.Stem Cell Rev Rep2011
19684026The interval between Ins2 and Ascl2 is dispensable for imprinting centre function in the murine Beckwith-Wiedemann region.Hum Mol Genet2009
17360283Mitotic recombination counteracts the benefits of genetic segregation.Proc Biol Sci2007
16817534A model of the evolution of dichogamy incorporating sex-ratio selection, anther-stigma interference, and inbreeding depression.Evolution2006
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Collaborators

Bruce R Conklin
Gladstone Institutes
Co-authored papers 13
Nathaniel Huebsch
Washington University in St. Louis
Co-authored papers 6
Po-Lin So
Gladstone Institutes
Co-authored papers 5
Deepak Srivastava
Gladstone Institutes San Francisco
Co-authored papers 4
Luke M Judge
Gladstone Institutes
Co-authored papers 4
Jennie Yoo
University of California San Francisco Department of Psychiatry
Co-authored papers 3
Annie Truong
Gladstone Institutes
Co-authored papers 3
Christopher Ian Spencer
Gladstone Institute of Cardiovascular Disease
Co-authored papers 3
Max A Horlbeck
Broad Institute of MIT and Harvard
Co-authored papers 2
Jonathan S Weissman
Whitehead Institute for Biomedical Research
Co-authored papers 2
Beth L Pruitt
University of California santa barbara
Co-authored papers 2
Alexandre J S Ribeiro
Center for Drug Evaluation and Research
Co-authored papers 2
Daniela Moralli
Co-authored papers 2
Tilde V Eskildsen
Odense University Hospital, University of Southern Denmark
Co-authored papers 2
Jacqueline E Villalta
University of California san francisco
Co-authored papers 2
S??ren P Sheikh
Odense University Hospital
Co-authored papers 2
Michael P Olvera
University of California san francisco
Co-authored papers 2
Farshad Farshidfar
Cumming School of Medicine, University of Calgary
Co-authored papers 2
Yuichiro Miyaoka
Tokyo Metropolitan Institute of Medical Science, Japan Gladstone Institutes
Co-authored papers 2
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 2
Luke A Gilbert
Arc Institute
Co-authored papers 2
Jonathon M Muncie
Gladstone Institutes
Co-authored papers 1
Valerie M Weaver
University of California san francisco
Co-authored papers 1
Kristin Holmes
Gladstone Institute of Cardiovascular Disease
Co-authored papers 1
Robyn M Kaake
J. David Gladstone Institutes
Co-authored papers 1
Jeremy A Squire
University of Sao Paulo
Co-authored papers 1
Edward C Shin
University of California san francisco
Co-authored papers 1
Tejal A Desai
University of California San Francisco
Co-authored papers 1
Howard Y Chang
Center for Personal Dynamic Regulomes, Stanford University
Co-authored papers 1
Aaron M Zorn
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