|
| 36729903 | Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency. | MAbs | 2023 |
| 36411391 | A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins. | Nat Chem Biol | 2023 |
| 37605043 | Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization. | Nat Struct Mol Biol | 2023 |
| 37345226 | Improved pharmacokinetics of HIV-neutralizing VRC01-class antibodies achieved by reduction of net positive charge on variable domain. | | 2023 |
| 36555641 | Antiviral Activity and Crystal Structures of HIV-1 gp120 Antagonists. | | 2022 |
| 35677079 | Potent and pan-neutralization of SARS-CoV-2 variants of concern by DARPins. | bioRxiv | 2022 |
| 35413243 | Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. | Structure | 2022 |
| 34328065 | A matrix of structure-based designs yields improved VRC01-class antibodies for HIV-1 therapy and prevention. | mAbs | 2021 |
| 34200826 | Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography. | Antibodies (Basel) | 2021 |
| 33827946 | Rational Engraftment of Quaternary-Interactive Acidic Loops for Anti-HIV-1 Antibody Improvement. | Journal of Virology | 2021 |
| 32561362 | The covalent SNAP tag for protein display quantification and low-pH protein engineering. | J Biotechnol | 2020 |
| 32348769 | HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies. | Cell Rep | 2020 |
| 31348886 | Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. | Cell | 2019 |
| 30876875 | Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual. | Immunity | 2019 |
| 31473167 | Safety and pharmacokinetics of broadly neutralising human monoclonal antibody VRC07-523LS in healthy adults: a phase 1 dose-escalation clinical trial. | Lancet HIV,The | 2019 |
| 29444432 | Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody. | Cell Rep | 2018 |
| 29867235 | Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1. | Nat Med | 2018 |
| 29860061 | Structure-based lead optimization to improve antiviral potency and ADMET properties of phenyl-1H-pyrrole-carboxamide entry inhibitors targeted to HIV-1 gp120. | European Journal of Medicinal Chemistry | 2018 |
| 28266845 | Synthesis, Antiviral Potency, in Vitro ADMET, and X-ray Structure of Potent CD4 Mimics as Entry Inhibitors That Target the Phe43 Cavity of HIV-1 gp120. | Journal of Medicinal Chemistry | 2017 |
| 28445724 | Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation. | Cell Rep | 2017 |
| 28931639 | Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques. | Science | 2017 |
| 28517931 | Correction to Synthesis, Antiviral Potency, in Vitro ADMET, and X-ray Structure of Potent CD4 Mimics as Entry Inhibitors That Target the Phe43 Cavity of HIV-1 gp120. | Journal of Medicinal Chemistry | 2017 |
| 29212041 | Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains. | Cell Reports | 2017 |
| 26949186 | Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody. | Cell | 2016 |
| 27114034 | Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G. | Cell | 2016 |
| 27053554 | Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design. | J Virol | 2016 |
| 26301736 | Structure-Based Design of a Small Molecule CD4-Antagonist with Broad Spectrum Anti-HIV-1 Activity. | Journal of Medicinal Chemistry | 2015 |
| 25800131 | Eliminating antibody polyreactivity through addition of N-linked glycosylation. | Protein Science | 2015 |
| 25865483 | Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. | Cell | 2015 |
| 26098315 | Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env. | Nat Struct Mol Biol | 2015 |
| 25001301 | Binding mode characterization of NBD series CD4-mimetic HIV-1 entry inhibitors by X-ray structure and resistance study. | Antimicrobial Agents and Chemotherapy | 2014 |
| 24489681 | Crystal structures of HIV-1 gp120 envelope glycoprotein in complex with NBD analogues that target the CD4-binding site. | PLoS ONE | 2014 |
| 25142607 | Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo. | J Virol | 2014 |
| 25165110 | Structural definition of an antibody-dependent cellular cytotoxicity response implicated in reduced risk for HIV-1 infection. | Journal of Virology | 2014 |
| 23707685 | Structural basis for highly effective HIV-1 neutralization by CD4-mimetic miniproteins revealed by 1.5 ÿ cocrystal structure of gp120 and M48U1. | Structure | 2013 |
| 23911655 | Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies. | Immunity | 2013 |
| 23843642 | Residue-level prediction of HIV-1 antibody epitopes based on neutralization of diverse viral strains. | Journal of Virology | 2013 |
| 23661761 | Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization. | Science | 2013 |
| 22142236 | Discovery and characterization of novel microRNAs during endothelial differentiation of human embryonic stem cells. | | 2012 |
| 22497421 | Structure-based design, synthesis, and characterization of dual hotspot small-molecule HIV-1 entry inhibitors. | Journal of Medicinal Chemistry | 2012 |
| 22524483 | Design, synthesis, and antiviral activity of entry inhibitors that target the CD4-binding site of HIV-1. | Journal of Medicinal Chemistry | 2012 |
| 22451932 | Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops. | Proc Natl Acad Sci U S A | 2012 |
| 23107345 | Effects of corticosteroid on the expressions of neuropeptide and cytokine mRNA and on tenocyte viability in lateral epicondylitis. | Journal of Inflammation | 2012 |
| 22113616 | Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. | Nature | 2011 |
| 21169023 | Design, synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screening. | Bioorganic and Medicinal Chemistry | 2011 |
| 20690185 | Interleukin-1β induces angiogenesis and innervation in human intervertebral disc degeneration. | Journal of Orthopaedic Research | 2011 |
| 20471426 | Conformational characterization of aberrant disulfide-linked HIV-1 gp120 dimers secreted from overexpressing cells. | Journal of Virological Methods | 2010 |
| 20624166 | Prognostic significance of Notch 3 gene expression in ovarian serous carcinoma. | Cancer Sci | 2010 |
| 20616231 | Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01. | Science | 2010 |
| 20080564 | Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility. | Proceedings of the National Academy of Sciences of the United States of America | 2010 |