Author details

Full Name

Bryan Paul Wordsworth

Affiliation

ORCID

Career Start Year

1980

Papers

306

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37388915	Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis.	Cell Genom	2023
36760998	Chromosome conformation capture approaches to investigate 3D genome architecture in Ankylosing Spondylitis.	Front Genet	2023
35069677	Disruption of c-MYC Binding and Chromosomal Looping Involving Genetic Variants Associated With Ankylosing Spondylitis Upstream of the <i>RUNX3</i> Promoter.	Front Genet	2022
34782440	Variable skeletal phenotypes associated with biallelic variants in <i>PRKG2</i>.	J Med Genet	2022
34825999	The Musculoskeletal Manifestations of Marfan Syndrome: Diagnosis, Impact, and Management.	Current Rheumatology Reports	2021
33746951	Perspectives on the Genetic Associations of Ankylosing Spondylitis.	Frontiers in Immunology	2021
34161253	Polygenic Risk Scores have high diagnostic capacity in ankylosing spondylitis.	Ann Rheum Dis	2021
34216293	MicroRNAs in Axial Spondylarthritis: an Overview of the Recent Progresses in the Field with a Focus on Ankylosing Spondylitis and Psoriatic Arthritis.	Current Rheumatology Reports	2021
33369221	Functional Genomic Analysis of a RUNX3 Polymorphism Associated With Ankylosing Spondylitis.	Arthritis Rheumatol	2021
35047859	Novel pathogenic variants and quantitative phenotypic analyses of Robinow syndrome: WNT signaling perturbation and phenotypic variability.	HGG Adv	2021
33574815	The IL-17/IL-23 Axis and Its Genetic Contribution to Psoriatic Arthritis.	Frontiers in Immunology	2020
32366894	Differences in intracellular localisation of ANKH mutants that relate to mechanisms of calcium pyrophosphate deposition disease and craniometaphyseal dysplasia.	Scientific Reports	2020
32123118	Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism.	Proc Natl Acad Sci U S A	2020
32492107	Genomewide Association Study of Acute Anterior Uveitis Identifies New Susceptibility Loci.	Invest Ophthalmol Vis Sci	2020
30989250	Melorheostosis and Osteopoikilosis: A Review of Clinical Features and Pathogenesis.	Calcified Tissue International	2019
31650700	The influence of genetics in musculoskeletal diseases: A personal review of progress over 40 years.	International Journal of Rheumatic Diseases	2019
29535371	The severity of ankylosing spondylitis and responses to anti-tumour necrosis factor biologics are not influenced by the tumour necrosis factor receptor polymorphism incriminated in multiple sclerosis.	Genes and Immunity	2019
29369795	Cardiovascular magnetic resonance characterization of myocardial and vascular function in rheumatoid arthritis patients.	Hellenic J Cardiol	2019
30687330	RUNX3 and T-Bet in Immunopathogenesis of Ankylosing Spondylitis-Novel Targets for Therapy?	Front Immunol	2019
31313512	PAPSS2-related brachyolmia: Clinical and radiological phenotype in 18 new cases.	Am J Med Genet A	2019
29702496	Quantifying the genetic risk for the development of axial spondyloarthropathy: could this become a diagnostic tool?	Current Opinion in Rheumatology	2018
30017519	Anti-TNF modulation reduces myocardial inflammation and improves cardiovascular function in systemic rheumatic diseases.	Int J Cardiol	2018
29531791	Evidence for a second ankylosing spondylitis-associated <i>RUNX3</i> regulatory polymorphism.	RMD Open	2018
28223525	Reply to Reeves et al.: No evidence for rare haplotypes and haplotype combinations in ankylosing spondylitis.	Proceedings of the National Academy of Sciences of the United States of America	2017
28381868	Investigation of a possible extended risk haplotype in the IL23R region associated with ankylosing spondylitis.	Genes Immun	2017
30509439	Genetics in ankylosing spondylitis - Current state of the art and translation into clinical outcomes.	Best Practice and Research in Clinical Rheumatology	2017
28049827	ERAP1 association with ankylosing spondylitis is attributable to common genotypes rather than rare haplotype combinations.	Proceedings of the National Academy of Sciences of the United States of America	2017
27825362	The RUDY study platform - a novel approach to patient driven research in rare musculoskeletal diseases.	Orphanet J Rare Dis	2016
29263810	Exome-wide study of ankylosing spondylitis demonstrates additional shared genetic background with inflammatory bowel disease.	NPJ Genom Med	2016
26916345	An ankylosing spondylitis-associated genetic variant in the IL23R-IL12RB2 intergenic region modulates enhancer activity and is associated with increased Th1-cell differentiation.	Ann Rheum Dis	2016
26610302	The genetic associations of acute anterior uveitis and their overlap with the genetics of ankylosing spondylitis.	Genes Immun	2016
26439405	Genetics of ankylosing spondylitis--insights into pathogenesis.	Nat Rev Rheumatol	2016
26248638	Long-term effects of secukinumab on MRI findings in relation to clinical efficacy in subjects with active ankylosing spondylitis: an observational study.	Annals of the Rheumatic Diseases	2016
26452539	The genetic association of RUNX3 with ankylosing spondylitis can be explained by allele-specific effects on IRF4 recruitment that alter gene expression.	Ann Rheum Dis	2016
27894323	Health-related quality of life and a cost-utility simulation of adults in the UK with osteogenesis imperfecta, X-linked hypophosphatemia and fibrous dysplasia.	Orphanet J Rare Dis	2016
24651623	Association study of genes related to bone formation and resorption and the extent of radiographic change in ankylosing spondylitis.	Ann Rheum Dis	2015
25917849	ERAP2 is associated with ankylosing spondylitis in HLA-B27-positive and HLA-B27-negative patients.	Ann Rheum Dis	2015
25890584	Diffuse Myocardial Fibrosis and Inflammation in Rheumatoid Arthritis: Insights From CMR T1 Mapping.	JACC Cardiovasc Imaging	2015
26561226	Chiari malformation, syringomyelia and bulbar palsy in X linked hypophosphataemia.	BMJ Case Reports	2015
26261308	CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses.	Proc Natl Acad Sci U S A	2015
25994336	Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1.	Nat Commun	2015
25200001	Genetic dissection of acute anterior uveitis reveals similarities and differences in associations observed with ankylosing spondylitis.	Arthritis Rheumatol	2015
25007883	A new acro-osteolysis syndrome caused by duplications including PTHLH.	J Hum Genet	2014
24449572	Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.	Arthritis and Rheumatology	2014
24593856	Subclinical myocardial inflammation and diffuse fibrosis are common in systemic sclerosis--a clinical study using myocardial T1-mapping and extracellular volume quantification.	J Cardiovasc Magn Reson	2014
25169729	Ankylosing spondylitis is associated with the anthrax toxin receptor 2 gene (ANTXR2).	Ann Rheum Dis	2014
24619796	Ankylosing spondylitis is associated with an increased risk of vertebral and nonvertebral clinical fractures: a population-based cohort study.	J Bone Miner Res	2014
25060790	Reciprocal effects of systemic inflammation and brain natriuretic peptide on adiponectin biosynthesis in adipose tissue of patients with ischemic heart disease.	Arteriosclerosis, Thrombosis, and Vascular Biology	2014
23452840	ERAP1 and ankylosing spondylitis.		2013
22527137	A CCR6 variant strongly associated with rheumatoid arthritis in two populations is not associated with ankylosing spondylitis.	Rheumatology International	2013