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Author Details

Thomas G P Gr??newald
German Cancer Research Center
2006
128
42
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37916971Translational Aspects of Epithelioid Sarcoma: Current Consensus.Clin Cancer Res2024
36915100Hypoxia and HIFs in Ewing sarcoma: new perspectives on a multi-facetted relationship.Mol Cancer2023
37286428A century of retroperitoneal soft-tissue sarcoma research: From single center experience to precision oncology? A bibliometric analysis of past, present, and future perspectives.Eur J Surg Oncol2023
36787739Targeted long-read sequencing of the Ewing sarcoma 6p25.1 susceptibility locus identifies germline-somatic interactions with EWSR1-FLI1 binding.Am J Hum Genet2023
35228525Eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) expression in glioblastoma is driven by ETS1- and MYBL2-dependent transcriptional activation.Cell Death Discov2022
35585241PHGDH heterogeneity potentiates cancer cell dissemination and metastasis.Nature2022
35550257Oncogenic chimeric transcription factors drive tumor-specific transcription, processing, and translation of silent genomic regions.Mol Cell2022
35839307Functional genomic analysis of epithelioid sarcoma reveals distinct proximal and distal subtype biology.Clin Transl Med2022
35379801EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma.Cell Death Discov2022
35459264Fusion protein-driven IGF-IR/PI3K/AKT signals deregulate Hippo pathway promoting oncogenic cooperation of YAP1 and FUS-DDIT3 in myxoid liposarcoma.Oncogenesis2022
36149602ABCA6 affects the malignancy of Ewing sarcoma cells via cholesterol-guided inhibition of the IGF1R/AKT/MDM2 axis.Cell Oncol (Dordr)2022
36070798Novel antigen-presenting cell imparts T<sub>reg</sub>-dependent tolerance to gut microbiota.Nature2022
36042336Author Correction: PHGDH heterogeneity potentiates cancer cell dissemination and metastasis.Nature2022
36202860Small round cell sarcomas.Nat Rev Dis Primers2022
35955799Endoglin and MMP14 Contribute to Ewing Sarcoma Spreading by Modulation of Cell-Matrix Interactions.Int J Mol Sci2022
36352194Correction to: ABCA6 affects the malignancy of Ewing sarcoma cells via cholesterol-guided inhibition of the IGF1R/AKT/MDM2 axis.Cell Oncol (Dordr)2022
36115869An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma.NPJ Precis Oncol2022
33908607MondoA drives malignancy in B-ALL through enhanced adaptation to metabolic stress.Blood2022
34980141Integrative gene network and functional analyses identify a prognostically relevant key regulator of metastasis in Ewing sarcoma.Mol Cancer2022
33479225Sarcoma classification by DNA methylation profiling.Nat Commun2021
33767450Single-cell transcriptomic analyses provide insights into the developmental origins of neuroblastoma.Nat Genet2021
33919988Ewing Sarcoma-Diagnosis, Treatment, Clinical Challenges and Future Perspectives.J Clin Med2021
33687947Fat Induces Glucose Metabolism in Nontransformed Liver Cells and Promotes Liver Tumorigenesis.Cancer Res2021
35121888Super enhancers define regulatory subtypes and cell identity in neuroblastoma.Nat Cancer2021
34830820The Transcription Factor <i>FEZF1</i>, a Direct Target of <i>EWSR1-FLI1</i> in Ewing Sarcoma Cells, Regulates the Expression of Neural-Specific Genes.Cancers (Basel)2021
34531368Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer.Nat Commun2021
34341072Unraveling Ewing Sarcoma Tumorigenesis Originating from Patient-Derived Mesenchymal Stem Cells.Cancer Res2021
34315482Translational evidence for RRM2 as a prognostic biomarker and therapeutic target in Ewing sarcoma.Mol Cancer2021
33340488In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition.Mol Cell2021
33326093(Immuno)histological Analysis of Ewing Sarcoma.Methods Mol Biol2021
33326091Tissue Preservation and FFPE Samples: Optimized Nucleic Acids Isolation in Ewing Sarcoma.Methods Mol Biol2021
33326089Germline Variation and Somatic Alterations in Ewing Sarcoma.Methods Mol Biol2021
32222780A comparative view on the expression patterns of PD-L1 and PD-1 in soft tissue sarcomas.Cancer Immunol Immunother2020
31732966Integrative clinical transcriptome analysis reveals TMPRSS2-ERG dependency of prognostic biomarkers in prostate adenocarcinoma.Int J Cancer2020
32049009Transcriptional Programs Define Intratumoral Heterogeneity of Ewing Sarcoma at Single-Cell Resolution.Cell Rep2020
31768620DNA methylation-based profiling of uterine neoplasms: a novel tool to improve gynecologic cancer diagnostics.J Cancer Res Clin Oncol2020
31880317Hippo pathway effectors YAP1/TAZ induce an EWS-FLI1-opposing gene signature and associate with disease progression in Ewing sarcoma.J Pathol2020
33051146Expression of the EWSR1-FLI1 fusion oncogene in pancreas cells drives pancreatic atrophy and lipomatosis.Pancreatology2020
33047515Sarcoma treatment in the era of molecular medicine.EMBO Mol Med2020
33230121Publisher Correction: Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma.Nat Commun2020
32579932mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.Cell Rep2020
32944640SOX6: a double-edged sword for Ewing sarcoma.Mol Cell Oncol2020
32938628Leukemia escape in immune desert: intraocular relapse of pediatric pro-B-ALL during systemic control by CD19-CAR T cells.J Immunother Cancer2020
32881892Low-frequency variation near common germline susceptibility loci are associated with risk of Ewing sarcoma.PLoS One2020
32610710MHC Class I-Restricted TCR-Transgenic CD4<sup>+</sup> T Cells Against STEAP1 Mediate Local Tumor Control of Ewing Sarcoma In Vivo.Cells2020
32415069Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma.Nat Commun2020
32235444Pan-Cancer Analysis of Mitochondria Chaperone-Client Co-Expression Reveals Chaperone Functional Partitioning.Cancers (Basel)2020
32164354High Specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG Positive Ewing Sarcoma.Cancers (Basel)2020
32483603Endogenous TCR promotes in vivo persistence of CD19-CAR-T cells compared to a CRISPR/Cas9-mediated TCR knockout CAR.Blood2020
30267407Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma.Int J Cancer2019
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Collaborators

Technische Universitat Munchen
Co-authored papers 26
Hopp-Children's Cancer Center (KiTZ)
Co-authored papers 23
University Hospital Essen, West German Cancer Center
Co-authored papers 21
PSL Research University, Institut Curie Research Center, INSERM U, Institut Curie
Co-authored papers 20
Children's Cancer Research Center
Co-authored papers 16
Balgrist University Hospital, University of Zurich (UZH)
Co-authored papers 14
Servicio de Anatomia Patologica. Hospital Universitario Virgen del Rocio.
Co-authored papers 12
Cancer Center of Lyon
Co-authored papers 9
Co-authored papers 8
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 7
Ben-Gurion University of the Negev
Co-authored papers 6
Institut Curie Hospital
Co-authored papers 6
St. Anna Children's Cancer Research Institute (CCRI), Medical University Vienna
Co-authored papers 6
Institute of Neuropathology, Heinrich-Heine University Dusseldorf
Co-authored papers 6
British Columbia Cancer Research Centre
Co-authored papers 6
University Hospital Erlangen
Co-authored papers 6
Children's Hospital of Los Angeles
Co-authored papers 5
Co-authored papers 5
National Cancer Institute
Co-authored papers 5
Institut Curie
Co-authored papers 5
Memorial Sloan Kettering Cancer Center
Co-authored papers 4
German Research Center for Environmental Health, Institute of Genetic Epidemiology
Co-authored papers 4
Co-authored papers 4
Institute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham
Co-authored papers 4
Centre Leon Berard & Universite Claude Bernard
Co-authored papers 4
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 4
National Cancer Institute, National Institutes of Health
Co-authored papers 4
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 4
Co-authored papers 4
INSERM UMR 3, Imagine Institute
Co-authored papers 3