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Author Details

Holger Heyn
Barcelona Institute of Science and Technology, Spain Universitat Pompeu Fabra
1988
102
48
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37337297The effect of background noise and its removal on the analysis of single-cell expression data.Genome Biol2023
37563469Metabolic rewiring induced by ranolazine improves melanoma responses to targeted therapy and immunotherapy.Nat Metab2023
37291218Targeting lymphoid-derived IL-17 signaling to delay skin aging.Nat Aging2023
37149862Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin.Cell Rep2023
35172160Modeling iPSC-derived human neurofibroma-like tumors in mice uncovers the heterogeneity of Schwann cells within plexiform neurofibromas.Cell Rep2022
35773527Mex3a marks drug-tolerant persister colorectal cancer cells that mediate relapse after chemotherapy.Nat Cancer2022
35672297ATM germline variants in a young adult with chronic lymphocytic leukemia: 8â¿¿years of genomic evolution.Blood Cancer J2022
35603814Controlled X-chromosome dynamics defines meiotic potential of female mouse in vitro germ cells.EMBO J2022
35365635Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses.Nat Commun2022
35821254Author Correction to: SARS-CoV-2 interaction with Siglec-1 mediates trans-infection by dendritic cells.Cell Mol Immunol2022
35859028The emerging landscape of spatial profiling technologies.Nat Rev Genet2022
36470887Correction: ATM germline variants in a young adult with chronic lymphocytic leukemia: 8 years of genomic evolution.Blood Cancer J2022
36202974The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A.Nat Cell Biol2022
35896525Cohesin couples transcriptional bursting probabilities of inducible enhancers and promoters.Nat Commun2022
35953718Detection of early seeding of Richter transformation in chronic lymphocytic leukemia.Nat Med2022
36352230Metastatic recurrence in colorectal cancer arises from residual EMP1<sup>+</sup> cells.Nature2022
33397934The order and logic of CD4 versus CD8 lineage choice and differentiation in mouse thymus.Nat Commun2021
33686071Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment.Nat Commun2021
33908703Single human oocyte transcriptome analysis reveals distinct maturation stage-dependent pathways impacted by age.Aging Cell2021
33544846SPOTlight: seeded NMF regression to deconvolute spatial transcriptomics spots with single-cell transcriptomes.Nucleic Acids Res2021
34759321Dietary palmitic acid promotes a prometastatic memory via Schwann cells.Nature2021
34782760SARS-CoV-2 interaction with Siglec-1 mediates trans-infection by dendritic cells.Cell Mol Immunol2021
34010627Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development.Cell Stem Cell2021
32396863Zonation of Ribosomal DNA Transcription Defines a Stem Cell Hierarchy in Colorectal Cancer.Cell Stem Cell2020
32051003Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data.Genome Biol2020
32821835The Polycomb-associated factor PHF19 controls hematopoietic stem cell state and differentiation.Sci Adv2020
32670419Use of patient derived orthotopic xenograft models for real-time therapy guidance in a pediatric sporadic malignant peripheral nerve sheath tumor.Ther Adv Med Oncol2020
32393363Sampling time-dependent artifacts in single-cell genomics studies.Genome Biol2020
32518403Benchmarking single-cell RNA-sequencing protocols for cell atlas projects.Nat Biotechnol2020
30860479Single cell RNA-seq identifies the origins of heterogeneity in efficient cell transdifferentiation and reprogramming.Elife2019
31291573Three-Dimensional Genomic Structure and Cohesin Occupancy Correlate with Transcriptional Activity during Spermatogenesis.Cell Rep2019
31402335GATA2 Promotes Hematopoietic Development and Represses Cardiac Differentiation of Human Mesoderm.Stem Cell Reports2019
31159854Single-cell transcriptomics unveils gene regulatory network plasticity.Genome Biol2019
29736028PM20D1 is a quantitative trait locus associated with Alzheimer's disease.Nat Med2018
30415840Identity Noise and Adipogenic Traits Characterize Dermal Fibroblast Aging.Cell2018
30446749Tutorial: guidelines for the experimental design of single-cell RNA sequencing studies.Nat Protoc2018
29724792bigSCale: an analytical framework for big-scale single-cell data.Genome Res2018
29625051Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation.Cell2018
27923837The NCI-60 Methylome and Its Integration into CellMiner.Cancer Res2017
28105729Whole genome grey and white matter DNA methylation profiles in dorsolateral prefrontal cortex.Synapse2017
28249587Single-cell transcriptome conservation in cryopreserved cells and tissues.Genome Biol2017
28212749Comparative Analysis of Single-Cell RNA Sequencing Methods.Mol Cell2017
28288143DNMT3A mutations mediate the epigenetic reactivation of the leukemogenic factor MEIS1 in acute myeloid leukemia.Oncogene2017
28344317Epigenetic loss of the RNA decapping enzyme NUDT16 mediates C-MYC activation in T-cell acute lymphoblastic leukemia.Leukemia2017
28285904Mex3a Marks a Slowly Dividing Subpopulation of Lgr5+ Intestinal Stem Cells.Cell Stem Cell2017
28961841Dual MET and ERBB inhibition overcomes intratumor plasticity in osimertinib-resistant-advanced non-small-cell lung cancer (NSCLC).Ann Oncol2017
29198826TRIM28 and Interacting KRAB-ZNFs Control Self-Renewal of Human Pluripotent Stem Cells through Epigenetic Repression of Pro-differentiation Genes.Stem Cell Reports2017
28883545Copy number rather than epigenetic alterations are the major dictator of imprinted methylation in tumors.Nat Commun2017
28538178Wolf-Hirschhorn Syndrome Candidate 1 Is Necessary for Correct Hematopoietic and B Cell Development.Cell Rep2017
28581523A DNA methylation map of human cancer at single base-pair resolution.Oncogene2017
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Collaborators

Ivo Gut
Spain Universitat de Barcelona (UB)
Co-authored papers 9
Marta Gut
Universitat de Barcelona (UB)
Co-authored papers 8
Ultan McDermott
Wellcome Sanger Institute
Co-authored papers 4
Elias Campo
Institute for Biomedical Research August Pi I Sunyer
Co-authored papers 4
Oliver Stegle
Wellcome Sanger Institute
Co-authored papers 3
Joaqu??n Dopazo
Andalusian Public Foundation Progress and Health-FPS
Co-authored papers 3
Tomas Marques-Bonet
University of California san francisco
Co-authored papers 3
Xose S Puente
University of Oviedo
Co-authored papers 3
Nuria Lopez-Bigas
Universitat Pompeu Fabra
Co-authored papers 3
Simon Heath
Barcelona Institute of Science and Technology (BIST)
Co-authored papers 2
Sudhir Varma
Center for Cancer Research, National Cancer Institute
Co-authored papers 2
David Torrents
Institucio Catalana de Recerca i Estudis Avancats (ICREA)
Co-authored papers 2
Juan Pablo Albar
National Center for Biotechnology
Co-authored papers 2
Benjamin Trinité
Co-authored papers 2
Christoph Bock
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 2
J??lia Vergara-Alert
Campus de la Universitat Autonoma de Barcelona (UAB)
Co-authored papers 2
Julio Saez-Rodriguez
Institute of Computational Biomedicine, Heidelberg University
Co-authored papers 2
Yassen Assenov
German Cancer Research Center (DKFZ)
Co-authored papers 2
Matthew D Schultz
Co-authored papers 2
Nuria Izquierdo-Useros
IrsiCaixa AIDS Research Institute, Hospital Universitari Germans Trias i Pujol
Co-authored papers 2
Jordi Rodon
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Yves Pommier
Center for Cancer Research, National Cancer Institute
Co-authored papers 2
Matthew B Boxer
Co-authored papers 2
Roger Paredes
Hospital Germans Trias i Pujol
Co-authored papers 2
Joseph R Ecker
The Salk Institute for Biological Studies
Co-authored papers 2
William C Reinhold
Center for Cancer Research, National Cancer Institute
Co-authored papers 2
Maciej Wiznerowicz
Co-authored papers 2
Liewei Wang
Mayo Clinic
Co-authored papers 2
Amalio Telenti
Vir Biotechnology Inc.
Co-authored papers 2
Bonaventura Clotet
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