Author details

Full Name

Chunxu Qu

Affiliation

ORCID

Career Start Year

1992

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37453060	Stromal-induced epithelial-mesenchymal transition induces targetable drug resistance in acute lymphoblastic leukemia.	Cell Rep	2023
37986997	Biologic and clinical features of childhood gamma delta T-ALL: identification of STAG2/LMO2 Î³Î´ T-ALL as an extremely high risk leukemia in the very young.	medRxiv	2023
34662891	VpreB surrogate light chain expression in B-lineage ALL: a report from the Children's Oncology Group.	Blood Adv	2022
35590059	Acute lymphoblastic leukemia displays a distinct highly methylated genome.	Nat Cancer	2022
35513723	CCL22 mutations drive natural killer cell lymphoproliferative disease by deregulating microenvironmental crosstalk.	Nat Genet	2022
36034595	Rare disease-based scientific annotation knowledge graph.	Frontiers in Artificial Intelligence	2022
36050548	The genomic landscape of pediatric acute lymphoblastic leukemia.	Nat Genet	2022
34991158	G3BP2-KIT drives leukemia amenable to kinase inhibition in Ph-like ALL.	Blood Adv	2022
35247902	ZNF384 Fusion Oncoproteins Drive Lineage Aberrancy in Acute Leukemia.	Blood Cancer Discov	2022
34903620	Phase Separation Mediates NUP98 Fusion Oncoprotein Leukemic Transformation.	Cancer Discov	2022
34907175	Interleukin-7 receptor Î± mutational activation can initiate precursor B-cell acute lymphoblastic leukemia.	Nat Commun	2021
33593877	Venetoclax and Navitoclax in Combination with Chemotherapy in Patients with Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma.	Cancer Discov	2021
33895809	Molecular classification improves risk assessment in adult BCR-ABL1-negative B-ALL.	Blood	2021
34110416	Degradation of Janus kinases in CRLF2-rearranged acute lymphoblastic leukemia.	Blood	2021
34103329	Enhancer Hijacking Drives Oncogenic <i>BCL11B</i> Expression in Lineage-Ambiguous Stem Cell Leukemia.	Cancer Discov	2021
33512458	Modeling and targeting of erythroleukemia by hematopoietic genome editing.	Blood	2021
34250504	Clinical significance of novel subtypes of acute lymphoblastic leukemia in the context of minimal residual disease-directed therapy.	Blood Cancer Discov	2021
32881995	Tumor-intrinsic and -extrinsic determinants of response to blinatumomab in adults with B-ALL.	Blood	2021
32470390	Extensive Remodeling of the Immune Microenvironment in B Cell Acute Lymphoblastic Leukemia.	Cancer Cell	2020
30804683	PTPN9 induces cell apoptosis by mitigating the activation of Stat3 and acts as a tumor suppressor in colorectal cancer.	Cancer Management and Research	2019
30595505	Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression.	Cancer Cell	2019
30643249	PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia.	Nat Genet	2019
30926971	Genomic subtyping and therapeutic targeting of acute erythroleukemia.	Nat Genet	2019
29681510	Germline Genetic IKZF1 Variation and Predisposition to Childhood Acute Lymphoblastic Leukemia.	Cancer Cell	2018
29855693	Targeting ALK in pediatric RMS does not induce antitumor activity in vivo.	Cancer Chemother Pharmacol	2018
27815386	PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation.	Cancer Res	2017
28684529	Targeting Histone Demethylases in MYC-Driven Neuroblastomas with Ciclopirox.	Cancer Res	2017
27622269	c-Fos Repression by Piwi Regulates Drosophila Ovarian Germline Formation and Tissue Morphogenesis.	PLoS Genetics	2016
27105116	SHREC Silences Heterochromatin via Distinct Remodeling and Deacetylation Modules.	Molecular Cell	2016
27798625	The genomic landscape of core-binding factor acute myeloid leukemias.	Nat Genet	2016
27776115	Deregulation of DUX4 and ERG in acute lymphoblastic leukemia.	Nat Genet	2016
25987655	Genome-wide analysis links NFATC2 with asparaginase hypersensitivity.	Blood	2015
25925418	The role of histone demethylase KDM4B in Myc signaling in neuroblastoma.	J Natl Cancer Inst	2015
25863122	Development and characterization of a human orthotopic neuroblastoma xenograft.	Dev Biol	2015
25855603	PAX5 is a tumor suppressor in mouse mutagenesis models of acute lymphoblastic leukemia.	Blood	2015
26321221	Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia.	Cancer Cell	2015
26140606	Quantification of Retinogenesis in 3D Cultures Reveals Epigenetic Memory and Higher Efficiency in iPSCs Derived from Rod Photoreceptors.	Cell Stem Cell	2015
26598706	Estrogen receptor-Î± directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer.	Proc Natl Acad Sci U S A	2015
25249627	Genome-wide and single-cell analyses reveal a context dependent relationship between CBP recruitment and gene expression.	Nucleic Acids Research	2014
24705251	The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma.	Nat Genet	2014
24703847	Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma.	Cell Rep	2014
24332040	Targeting oxidative stress in embryonal rhabdomyosarcoma.	Cancer Cell	2013
23970477	Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas.	Cancer Res	2013
22286216	Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas.	Nat Genet	2012
22542874	Long-lasting transcriptional refractoriness triggered by a single exposure to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine.	Neuroscience	2012
22470460	Methylphenidate exposure induces dopamine neuron loss and activation of microglia in the basal ganglia of mice.	PLoS ONE	2012
22340591	A mouse model of the most aggressive subgroup of human medulloblastoma.	Cancer Cell	2012
21931021	Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma.	J Clin Oncol	2011
21397855	Cooperativity within and among Pten, p53, and Rb pathways induces high-grade astrocytoma in adult brain.	Cancer Cell	2011
20516124	Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells.	Cancer Res	2010