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Author Details

Youngchang Kim
Argonne National Laboratory
1993
110
42
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36201627Crystal structure of Campylobacter jejuni lipoprotein Cj1090c.Proteins2023
37747257A high-throughput structural system biology approach to increase structure representation of proteins from <i>Clostridioides difficile</i>.Microbiol Resour Announc2023
37548665Structure and enzymatic characterization of CelD endoglucanase from the anaerobic fungus Piromyces finnis.Appl Microbiol Biotechnol2023
36989297Identification of a broadly conserved family of enzymes that hydrolyze (p)ppApp.Proc Natl Acad Sci U S A2023
35195438Functional and Structural Characterization of Diverse NfsB Chloramphenicol Reductase Enzymes from Human Pathogens.Microbiol Spectr2022
35435721A Genomic Island of Vibrio cholerae Encodes a Three-Component Cytotoxin with Monomer and Protomer Forms Structurally Similar to Alpha-Pore-Forming Toxins.J Bacteriol2022
36450742Time-resolved β-lactam cleavage by L1 metallo-β-lactamase.Nat Commun2022
36073872Fixed-target serial crystallography at the Structural Biology Center.J Synchrotron Radiat2022
36036513Dual Targeting Factors Are Required for LXG Toxin Export by the Bacterial Type VIIb Secretion System.mBio2022
35916224Data collection from crystals grown in microfluidic droplets.Acta Crystallogr D Struct Biol2022
35876256The first crystal structure of a xylobiose-bound xylobiohydrolase with high functional specificity from the bacterial glycoside hydrolase family 30, subfamily 10.FEBS Lett2022
33238147Structure of the Extracellular Region of the Bacterial Type VIIb Secretion System Subunit EsaA.Structure2021
33564093Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2.Commun Biol2021
33531496Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors.Nat Commun2021
34590817The Enzymatic Activity of Inosine 5'-Monophosphate Dehydrogenase May Not Be a Vulnerable Target for <i>Staphylococcus aureus</i> Infections.ACS Infect Dis2021
34776222An efficient chemical screening method for structure-based inhibitors to nucleic acid enzymes targeting the DNA repair-replication interface and SARS CoV-2.Methods Enzymol2021
34561912Target highlights in CASP14: Analysis of models by structure providers.Proteins2021
34197805Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication.Biophys J2021
339724102'-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography.Proc Natl Acad Sci U S A2021
32511376The crystal structure of nsp10-nsp16 heterodimer from SARS-CoV-2 in complex with S-adenosylmethionine.bioRxiv2020
31846104Structural and biochemical analysis of the metallo-β-lactamase L1 from emerging pathogen Stenotrophomonas maltophilia revealed the subtle but distinct di-metal scaffold for catalytic activity.Protein Sci2020
31762145Structural and functional characterization of three Type B and C chloramphenicol acetyltransferases from Vibrio species.Protein Sci2020
32939273Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes.IUCrJ2020
30536925Periplasmic protein EipA determines envelope stress resistance and virulence in Brucella abortus.Mol Microbiol2019
30804532Bidirectional modulation of HIF-2 activity through chemical ligands.Nat Chem Biol2019
30936371<i>Brucella</i> Periplasmic Protein EipB Is a Molecular Determinant of Cell Envelope Integrity and Virulence.J Bacteriol2019
30746940Oxanosine Monophosphate Is a Covalent Inhibitor of Inosine 5'-Monophosphate Dehydrogenase.Chem Res Toxicol2019
29567835Molecular control of gene expression by <i>Brucella</i> BaaR, an IclR-type transcriptional repressor.J Biol Chem2018
30241610Structural Basis of Smoothened Activation in Hedgehog Signaling.Cell2018
29804838Structural Basis of Smoothened Activation in Hedgehog Signaling.Cell2018
30168204Crystal structure of the ligand-binding domain of a LysR-type transcriptional regulator: transcriptional activation via a rotary switch.Mol Microbiol2018
27994018Conserved ABC Transport System Regulated by the General Stress Response Pathways of Alpha- and Gammaproteobacteria.J Bacteriol2017
29021580The quaternary architecture of RARβ-RXRα heterodimer facilitates domain-domain signal transmission.Nat Commun2017
28884166Crystal Structure of Thioesterase SgcE10 Supporting Common Polyene Intermediates in 9- and 10-Membered Enediyne Core Biosynthesis.ACS Omega2017
28614901X-ray crystal structures of the pheromone-binding domains of two quorum-hindered transcription factors, YenR of Yersinia enterocolitica and CepR2 of Burkholderia cenocepacia.Proteins2017
26858101WrpA Is an Atypical Flavodoxin Family Protein under Regulatory Control of the Brucella abortus General Stress Response System.J Bacteriol2016
27782878NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors.Elife2016
27536006A microbial sensor for organophosphate hydrolysis exploiting an engineered specificity switch in a transcription factor.Nucleic Acids Res2016
27406907Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027.J Antibiot (Tokyo)2016
27545348Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling.Cell2016
27129205How Aromatic Compounds Block DNA Binding of HcaR Catabolite Regulator.J Biol Chem2016
25562780Kinetic gating mechanism of DNA damage recognition by Rad4/XPC.Nat Commun2015
26440283Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds.PLoS One2015
26438537A novel transcriptional regulator of L-arabinose utilization in human gut bacteria.Nucleic Acids Res2015
26245371Structural integration in hypoxia-inducible factors.Nature2015
26420866Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.Proc Natl Acad Sci U S A2015
26061967Structural characterization of AtmS13, a putative sugar aminotransferase involved in indolocarbazole AT2433 aminopentose biosynthesis.Proteins2015
25945705Structure of Cryptosporidium IMP dehydrogenase bound to an inhibitor with in vivo antiparasitic activity.Acta Crystallogr F Struct Biol Commun2015
25572472A novel cofactor-binding mode in bacterial IMP dehydrogenases explains inhibitor selectivity.J Biol Chem2015
24590711Protein production for structural genomics using E. coli expression.Methods Mol Biol2014
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Collaborators

Andrzej Joachimiak
Center for Structural Biology of Infectious Diseases, University of Chicago
Co-authored papers 66
Gyorgy Babnigg
Argonne National Laboratory
Co-authored papers 18
Min Zhou
College of Materials Science and Engineering, Hunan University
Co-authored papers 9
Ruiying Wu
Argonne National Laboratory
Co-authored papers 9
Lucy Stols
Midwest Center for Structural Genomics, Argonne National Laboratory
Co-authored papers 8
Aled M Edwards
University of Toronto
Co-authored papers 8
Alexei Savchenko
University of Toronto
Co-authored papers 8
Cheryl H Arrowsmith
University of Toronto
Co-authored papers 7
Irina Dementieva
Northwestern University, Feinberg School of Medicine
Co-authored papers 6
William H Eschenfeldt
Midwest Center for Structural Genomics, Argonne National Laboratory
Co-authored papers 6
Sean Crosson
Co-authored papers 5
Mark I Donnelly
Midwest Center for Structural Genomics, Argonne National Laboratory
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George N Phillips
Rice University
Co-authored papers 4
Frank R Collart
Argonne National Laboratory
Co-authored papers 4
Piotr Gornicki
University of Chicago
Co-authored papers 3
Wladek Minor
University of Virginia
Co-authored papers 3
Lukasz Jaroszewski
University of California Riverside School of Medicine
Co-authored papers 2
Johan Weigelt
Karolinska Institutet
Co-authored papers 2
Susanne Gr??slund
Karolinska Institutet
Co-authored papers 2
Jeffrey D Rudolf
University of Florida
Co-authored papers 2
Adam Godzik
University of California Riverside
Co-authored papers 2
Adelinda Yee
University of Toronto
Co-authored papers 2
Raymond Hui
University of Toronto
Co-authored papers 2
Andrew C Kruse
Blavatnik Institute, Harvard Medical School
Co-authored papers 2
Robert Haselkorn
University of Chicago
Co-authored papers 2
P??r Nordlund
Karolinska Institutet, BioClinicum J6
Co-authored papers 2
Sirano Dhe-Paganon
Dana-Farber Cancer Institute
Co-authored papers 2
Maksymilian Chruszcz
University of South Carolina, Michigan State University
Co-authored papers 2
John A Tainer
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Hee-Won Park
Kangwon National University College of Medicine
Co-authored papers 2
Release 1.2