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Author Details

John J P Kastelein
1985
896
140
PMIDPaper TitleJournal TitlePublished Year
38065715Lipoprotein(a) levels and carotid intima-media thickness in children: A 20-year follow-up study.J Clin Lipidol2024
37487514Lipoprotein(a) and carotid intima-media thickness in children with familial hypercholesterolaemia in the Netherlands: a 20-year follow-up study.Lancet Diabetes Endocrinol2023
36307922Comparison of low-density lipoprotein cholesterol equations in patients with dyslipidaemia receiving cholesterol ester transfer protein inhibition.European Heart Journal - Cardiovascular Pharmacotherapy2023
37855448Evolocumab in paediatric heterozygous familial hypercholesterolaemia: cognitive function during 80 weeks of open-label extension treatment.2023
37850379Efficacy, Safety, and Tolerability of Inclisiran in Patients With Homozygous Familial Hypercholesterolemia: Results From the ORION-5 Randomized Clinical Trial.2023
37840587Intima-media thickness at the near or far wall of the common carotid artery in cardiovascular risk assessment.Eur Heart J Open2023
37898443The evolving role of cholesteryl ester transfer protein inhibition beyond cardiovascular disease.2023
37277261Obicetrapib plus ezetimibe as an adjunct to high-intensity statin therapy: A randomized phase 2 trial.J Clin Lipidol2023
37398493CETP and SGLT2 inhibitor combination therapy improves glycemic control.2023
36697324Adherence to statin treatment in patients with familial hypercholesterolemia: A dynamic prediction model.2023
37355760The FGF21 analog pegozafermin in severe hypertriglyceridemia: a randomized phase 2 trial.Nat Med2023
37354546Bempedoic Acid for Primary Prevention of Cardiovascular Events in Statin-Intolerant Patients.2023
34636884Combination lipid-lowering therapy as first-line strategy in very high-risk patients.Eur Heart J2022
36047306Pharmacotherapy for children with elevated levels of lipoprotein(a): future directions.Expert Opinion on Pharmacotherapy2022
35648418Macular Degeneration and CETP Inhibition.JAMA Cardiology2022
35953719Lipid lowering effects of the CETP inhibitor obicetrapib in combination with high-intensity statins: a randomized phase 2 trial.Nature Medicine2022
35441656The effect of CETP inhibitors on new-onset diabetes: a systematic review and meta-analysis.Eur Heart J Cardiovasc Pharmacother2022
35757719Clinical Significance of Serum Albumin and Implications of FcRn Inhibitor Treatment in IgG-Mediated Autoimmune Disorders.Frontiers in Immunology2022
36345867Can we revive CETP-inhibitors for the prevention of cardiovascular disease?Current Opinion in Lipidology2022
36012684Cholesteryl Ester Transfer Protein Inhibition Reduces Major Adverse Cardiovascular Events by Lowering Apolipoprotein B Levels.International Journal of Molecular Sciences2022
35379578Homozygous familial hypercholesterolemia in China: Genetic and clinical characteristics from a real-world, multi-center, cohort study.Journal of Clinical Lipidology2022
36210291Cognitive function with evolocumab in pediatric heterozygous familial hypercholesterolemia.Journal of Clinical Lipidology2022
36075246Paediatric patients with heterozygous familial hypercholesterolaemia treated with evolocumab for 80 weeks (HAUSER-OLE): a single-arm, multicentre, open-label extension of HAUSER-RCT.Lancet Diabetes and Endocrinology,The2022
35361488Lipoprotein(a) levels from childhood to adulthood: Data in nearly 3,000 children who visited a pediatric lipid clinic.Atherosclerosis2022
36443827Personalized management of dyslipidemias in patients with diabetes-it is time for a new approach (2022).Cardiovasc Diabetol2022
36252994Lipoprotein(a) levels in a global population with established atherosclerotic cardiovascular disease.Open Heart2022
34922870Determinants of Plaque Progression Despite Very Low Low-Density Lipoprotein-Cholesterol Levels With the PCSK9 Inhibitor, Evolocumab.JACC: Cardiovascular Imaging2022
34915054A structurally engineered fatty acid, icosabutate, suppresses liver inflammation and fibrosis in NASH.Journal of Hepatology2022
35232215A Head-to-Head Comparison of a Free Fatty Acid Formulation of Omega-3 Pentaenoic Acids Versus Icosapent Ethyl in Adults With Hypertriglyceridemia: The ENHANCE-IT Study.J Am Heart Assoc2022
34849601Cholesteryl ester transfer protein inhibitors: from high-density lipoprotein cholesterol to low-density lipoprotein cholesterol lowering agents?Cardiovascular Research2022
35331419Resmetirom (MGL-3196) in Patients With Heterozygous Familial Hypercholesterolemia.Journal of the American College of Cardiology2022
34696496Longitudinal Assessment of Lipoprotein(a) Levels in Perinatally HIV-Infected Children and Adolescents.Viruses2021
32243492Effect of inclisiran, the small-interfering RNA against proprotein convertase subtilisin/kexin type 9, on platelets, immune cells, and immunological biomarkers: a pre-specified analysis from ORION-1.Cardiovasc Res2021
33901739A meta-analysis of medications directed against PCSK9 in familial hypercholesterolemia.Atherosclerosis2021
33470195Rationale and design of the CLEAR-outcomes trial: Evaluating the effect of bempedoic acid on cardiovascular events in patients with statin intolerance.American Heart Journal2021
33993205Association Between Achieved Ï¿-3 Fatty Acid Levels and Major Adverse Cardiovascular Outcomes in Patients With High Cardiovascular Risk: A Secondary Analysis of the STRENGTH Trial.JAMA Cardiol2021
33668055Comment on: Proprotein convertase subtilisin/kexin type 9 in the dyslipidaemia of patients with axial spondyloarthritis is related to disease activity.Rheumatology2021
34263698Beyond the Usual Suspects: Expanding on Mutations and Detection for Familial Hypercholesterolemia.Expert Review of Molecular Diagnostics2021
33663735Pooled Patient-Level Analysis of Inclisiran Trials in Patients With Familial Hypercholesterolemia or Atherosclerosis.J Am Coll Cardiol2021
33766264New and Emerging Therapies for Reduction of LDL-Cholesterol and Apolipoprotein B: JACC Focus Seminar 1/4.J Am Coll Cardiol2021
33497862LDL-cholesterol lowering and clinical outcomes in hypercholesterolemic subjects with and without a familial hypercholesterolemia phenotype: Analysis from the secondary prevention 4S trial.Atherosclerosis2021
33496768Update on Lipids and Lipoproteins-Reply.JAMA - Journal of the American Medical Association2021
33065120Rationale and design of ApoA-I Event Reducing in Ischemic Syndromes II (AEGIS-II): A phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to investigate the efficacy and safety of CSL112 in subjects after acute myocardial infarction.Am Heart J2021
34374706Erratum to "C-Reactive Protein Levels and Plaque Regression with Evolocumab: Insights From GLAGOV" [American Journal of Preventive Cardiology 3C (2020) 100091].Am J Prev Cardiol2021
32717042Lipids and Lipoproteins in 2020.JAMA - Journal of the American Medical Association2020
32187462Two Phase 3 Trials of Inclisiran in Patients with Elevated LDL Cholesterol.N Engl J Med2020
31630870Effects of Renal Impairment on the Pharmacokinetics, Efficacy, and Safety of Inclisiran: An Analysis of the ORION-7 and ORION-1 Studies.Mayo Clin Proc2020
32439006Familial Hypercholesterolemia: The Most Common Monogenic Disorder in Humans.Journal of the American College of Cardiology2020
34327467C-reactive protein levels and plaque regression with evolocumab: Insights from GLAGOV.Am J Prev Cardiol2020
32766688Inclisiran for the treatment of hypercholesterolaemia: implications and unanswered questions from the ORION trials.Cardiovascular Research2020
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