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Author Details

Marvin L Dirain
University of Florida College of Medicine
2006
30
15
PMIDPaper TitleJournal TitlePublished Year
35324554Sex differences associate with late microbiome alterations after murine surgical sepsis.J Trauma Acute Care Surg2022
35819783Evaluation of a Multivalent Transcriptomic Metric for Diagnosing Surgical Sepsis and Estimating Mortality Among Critically Ill Patients.JAMA Netw Open2022
33021571Single-Cell RNA-seq of Human Myeloid-Derived Suppressor Cells in Late Sepsis Reveals Multiple Subsets With Unique Transcriptional Responses: A Pilot Study.Shock2021
34956225Overlapping but Disparate Inflammatory and Immunosuppressive Responses to SARS-CoV-2 and Bacterial Sepsis: An Immunological Time Course Analysis.Front Immunol2021
34484194A Novel Single Cell RNA-seq Analysis of Non-Myeloid Circulating Cells in Late Sepsis.Front Immunol2021
33140449Transcriptomic responses from improved murine sepsis models can better mimic human surgical sepsis.FASEB J2021
32826817Septic Stability? Gut Microbiota in Young Adult Mice Maintains Overall Stability After Sepsis Compared to Old Adult Mice.Shock2021
31389840Old Mice Demonstrate Organ Dysfunction as well as Prolonged Inflammation, Immunosuppression, and Weight Loss in a Modified Surgical Sepsis Model.Crit Care Med2019
31722736Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis.Crit Care2019
28885387Evidence for Persistent Immune Suppression in Patients Who Develop Chronic Critical Illness After Sepsis.Shock2018
30300408Sepsis is associated with reduced spontaneous neutrophil migration velocity in human adults.PLoS One2018
29578343Human β-Defensin 1 and β-Defensin 3 (Mouse Ortholog mBD14) Function as Full Endogenous Agonists at Select Melanocortin Receptors.J Med Chem2018
28002685Effects of blood-flow restriction on biomarkers of myogenesis in response to resistance exercise.Appl Physiol Nutr Metab2017
28453292Discovery of Mixed Pharmacology Melanocortin-3 Agonists and Melanocortin-4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa<sup>1</sup>-Arg-(pI)DPhe-Xaa<sup>4</sup>-NH<sub>2</sub>.J Med Chem2017
27784315Intraoperative hemidiaphragm electrical stimulation reduces oxidative stress and upregulates autophagy in surgery patients undergoing mechanical ventilation: exploratory study.J Transl Med2016
26645732Synthesis and Structure-Activity Relationships of Substituted Urea Derivatives on Mouse Melanocortin Receptors.ACS Chem Neurosci2016
23493365Active muscle regeneration following eccentric contraction-induced injury is similar between healthy young and older adults.J Appl Physiol (1985)2014
253470331,4-disubstituted-[1,2,3]triazolyl-containing analogues of MT-II: design, synthesis, conformational analysis, and biological activity.J Med Chem2014
25141170Synthesis, biophysical, and pharmacological evaluation of the melanocortin agonist AST3-88: modifications of peptide backbone at Trp 7 position lead to a potent, selective, and stable ligand of the melanocortin 4 receptor (MC4R).ACS Chem Neurosci2014
24517312Identification of tetrapeptides from a mixture based positional scanning library that can restore nM full agonist function of the L106P, I69T, I102S, A219V, C271Y, and C271R human melanocortin-4 polymorphic receptors (hMC4Rs).J Med Chem2014
23432160Structure-activity relationships of peptides incorporating a bioactive reverse-turn heterocycle at the melanocortin receptors: identification of a 5800-fold mouse melanocortin-3 receptor (mMC3R) selective antagonist/partial agonist versus the mouse melanocortin-4 receptor (mMC4R).J Med Chem2013
22677927Blood flow restriction enhances post-resistance exercise angiogenic gene expression.Med Sci Sports Exerc2012
21306168Incorporation of a bioactive reverse-turn heterocycle into a peptide template using solid-phase synthesis to probe melanocortin receptor selectivity and ligand conformations by 2D 1H NMR.J Med Chem2011
20056544The effect of backbone cyclization on PK/PD properties of bioactive peptide-peptoid hybrids: the melanocortin agonist paradigm.Bioorg Med Chem2010
20462274Pharmacological characterization of 30 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists, synthetic agonists, and the endogenous agouti-related protein antagonist.Biochemistry2010
19096058The natural feed additive caprylic acid decreases Campylobacter jejuni colonization in market-aged broiler chickens.Poult Sci2009
19635667Semi-rigid tripeptide agonists of melanocortin receptors.Bioorg Med Chem Lett2009
18340004Caprylic acid supplemented in feed reduces enteric Campylobacter jejuni colonization in ten-day-old broiler chickens.Poult Sci2008
18502935Therapeutic supplementation of caprylic acid in feed reduces Campylobacter jejuni colonization in broiler chicks.Appl Environ Microbiol2008
17032837Effect of oral administration of bismuth compounds on Campylobacter colonization in broilers.Poult Sci2006
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Collaborators

University of Florida College of Medicine
Co-authored papers 11
University of Florida Health
Co-authored papers 11
University of Florida College of Medicine.
Co-authored papers 11
Harborview Medical Center, The University of Washington
Co-authored papers 10
University of Florida
Co-authored papers 9
Forensic and Scientific Services
Co-authored papers 9
University of Florida.
Co-authored papers 8
Institute on Aging, University of Florida
Co-authored papers 7
University of Florida
Co-authored papers 6
University of Florida, Univerzitet u Sarajevu Medicinski Fakultet
Co-authored papers 6
University of Florida College of Medicine
Co-authored papers 5
University of Florida Health
Co-authored papers 4
The Affiliated Hospital of Xuzhou Medical University
Co-authored papers 4
University of Florida
Co-authored papers 4
University of Florida College of Medicine
Co-authored papers 4
University of Florida
Co-authored papers 3
University of Florida
Co-authored papers 3
University of Alabama at Birmingham
Co-authored papers 3
Co-authored papers 3
University of Florida College of Public Health and Health Professions
Co-authored papers 3
Institute on Aging, University of Florida
Co-authored papers 3
Institute on Aging, University of Florida
Co-authored papers 3
University of Florida
Co-authored papers 3
University of Florida College of Medicine
Co-authored papers 3
College of Medicine, University of Florida
Co-authored papers 2
Loma Linda University
Co-authored papers 2
University of Florida
Co-authored papers 2
College of Medicine, University of Florida
Co-authored papers 2
University of Florida
Co-authored papers 2
University of Florida College of Medicine
Co-authored papers 2