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Author Details

Eytan Ruppin
National Cancer Institute
1971
316
68
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
38048593Transcriptional control of leukemogenesis by the chromatin reader SGF29.Blood2024
36631162Preclinical optimization of a GPC2-targeting CAR T-cell therapy for neuroblastoma.J Immunother Cancer2023
37859800Elevated A-to-I RNA editing in COVID-19 infected individuals.NAR Genom Bioinform2023
38076973Charting the transcriptomic landscape of primary and metastatic cancers in relation to their origin and target normal tissues.bioRxiv2023
37486616A comprehensive analysis of adverse events in the first 30 days of phase 1 pediatric CAR T-cell trials.Blood Adv2023
37852738Increased interleukin-6/C-reactive protein levels are associated with the upregulation of the adenosine pathway and serve as potential markers of therapeutic resistance to immune checkpoint inhibitor-based therapies in non-small cell lung cancer.J Immunother Cancer2023
37845222Expanding PROTACtable genome universe of E3 ligases.Nat Commun2023
37790315Prediction of cancer treatment response from histopathology images through imputed transcriptomics.Res Sq2023
37886558Deactivation of ligand-receptor interactions enhancing lymphocyte infiltration drives melanoma resistance to Immune Checkpoint Blockade.bioRxiv2023
37835579Pan-Cancer Analysis of Patient Tumor Single-Cell Transcriptomes Identifies Promising Selective and Safe Chimeric Antigen Receptor Targets in Head and Neck Cancer.Cancers (Basel)2023
37726418Biomarkers for immunotherapy of hepatocellular carcinoma.Nat Rev Clin Oncol2023
37090544Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency and Long-Term Risk of Immune-Related diseases.medRxiv2023
37459578Immune Resistance Mechanisms and the Road to Personalized Immunotherapy.Am Soc Clin Oncol Educ Book2023
37316351Single-cell methylation sequencing data reveal succinct metastatic migration histories and tumor progression models.Genome Res2023
37282346Glucose-6-Phosphate Dehydrogenase Deficiency and Coronavirus Disease 2019.Clin Infect Dis2023
37078793Ubiquitin Ligases Siah1a/2 Control Alveolar Macrophage Functions to Limit Carcinogen-Induced Lung Adenocarcinoma.Cancer Res2023
37380628A landscape of response to drug combinations in non-small cell lung cancer.Nat Commun2023
37308665The GPCR-Gα<sub>s</sub>-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure.Nat Immunol2023
37406115Melanoma-intrinsic NR2F6 activity regulates antitumor immunity.Sci Adv2023
37270587Optimizing cancer immunotherapy response prediction by tumor aneuploidy score and fraction of copy number alterations.NPJ Precis Oncol2023
37295398Medication effects on the gut microbiome in allo-HCT.Cell2023
36789444Decoupling the correlation between cytotoxic and exhausted T lymphocyte transcriptomic signatures enhances melanoma immunotherapy response prediction from tumor expression.bioRxiv2023
36789425Predicting tumor immune microenvironment and checkpoint therapy response of head &amp; neck cancer patients from blood immune single-cell transcriptomics.bioRxiv2023
36873924Altered gene expression in excitatory neurons is associated with Alzheimer's disease and its higher incidence in women.Alzheimers Dement (N Y)2023
36513065Clinically oriented prediction of patient response to targeted and immunotherapies from the tumor transcriptome.Med2023
36773602Genomic and transcriptomic analyses identify a prognostic gene signature and predict response to therapy in pleural and peritoneal mesothelioma.Cell Rep Med2023
34340996The tumour microenvironment shapes innate lymphoid cells in patients with hepatocellular carcinoma.Gut2022
35474866MPA<sub>PASS</sub> software enables stitched multiplex, multidimensional EV repertoire analysis and a standard framework for reporting bead-based assays.Cell Rep Methods2022
35610202Predicting cancer prognosis and drug response from the tumor microbiome.Nat Commun2022
35577818Author Correction: A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing.Nat Commun2022
35502318Synthetic lethality-based prediction of anti-SARS-CoV-2 targets.iScience2022
35632392Clinical and Laboratory Features in the Israeli Population with COVID-19 Infection after Pfizer-BioNTech mRNA Booster Vaccination.Vaccines (Basel)2022
35597871Gene-expression profiles of pretreatment biopsies predict complete response of rectal cancer patients to preoperative chemoradiotherapy.Br J Cancer2022
36600603Fibrolamellar carcinoma transcriptomic-based treatment prediction: complete response after nivolumab and ipilimumab.J Immunother Cancer2022
36497367Sex Biases in Cancer and Autoimmune Disease Incidence Are Strongly Positively Correlated with Mitochondrial Gene Expression across Human Tissues.Cancers (Basel)2022
36307411Strain level microbial detection and quantification with applications to single cell metagenomics.Nat Commun2022
36099885Race is a key determinant of the human intratumor microbiome.Cancer Cell2022
36064595Big data in basic and translational cancer research.Nat Rev Cancer2022
35899587Astrocyte immunometabolic regulation of the tumour microenvironment drives glioblastoma pathogenicity.Brain2022
35895872AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer.Cancer Discov2022
35921407Cross-species identification of cancer resistance-associated genes that may mediate human cancer risk.Sci Adv2022
35980743MCP-1/CCR2 axis inhibition sensitizes the brain microenvironment against melanoma brain metastasis progression.JCI Insight2022
36050469NRF2 mediates melanoma addiction to GCDH by modulating apoptotic signalling.Nat Cell Biol2022
34983745Deconvolving Clinically Relevant Cellular Immune Cross-talk from Bulk Gene Expression Using CODEFACS and LIRICS Stratifies Patients with Melanoma to Anti-PD-1 Therapy.Cancer Discov2022
35338126The landscape of receptor-mediated precision cancer combination therapy via a single-cell perspective.Nat Commun2022
35196484Nucleoporin-93 reveals a common feature of aggressive breast cancers: robust nucleocytoplasmic transport of transcription factors.Cell Rep2022
35018390Predicting COVID-19 severity using major risk factors and received vaccines.medRxiv2022
34555175Impact of the methylation classifier and ancillary methods on CNS tumor diagnostics.Neuro Oncol2022
33318707Publisher Correction: Mutation-selection balance and compensatory mechanisms in tumour evolution.Nat Rev Genet2021
33674593Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma.Nat Commun2021
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Collaborators

Tel Aviv University
Co-authored papers 46
Technion-Israel Institute of Technology
Co-authored papers 27
National Cancer Institute, National Institutes of Health
Co-authored papers 19
Center for Computational Biology, University of California berkeley
Co-authored papers 15
Co-authored papers 14
National Cancer Institute
Co-authored papers 12
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 12
Co-authored papers 11
Weizmann Institute of Science
Co-authored papers 8
Tel Aviv University
Co-authored papers 8
National Cancer Institute, National Institutes of Health
Co-authored papers 8
Center for Precision Health, University of Texas Health Science Center at Houston
Co-authored papers 7
University of Pittsburgh
Co-authored papers 6
Center for Cancer Research, National Cancer Institute (NCI)
Co-authored papers 6
Co-authored papers 6
Ellen and Ronald Caplan Cancer Center, The Wistar Institute
Co-authored papers 6
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 6
The Scripps Research Institute
Co-authored papers 5
The Scripps Research Institute
Co-authored papers 5
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 5
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 5
Co-authored papers 5
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 5
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 5
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 4
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 4
National Cancer Institute, National Institutes of Health
Co-authored papers 4
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 4
Argonne National Laboratory
Co-authored papers 4
Co-authored papers 3