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Author Details
Full Name
Edgar Hartsuiker
Affiliation
North West Cancer Research Institute, Bangor University
ORCID
Career Start Year
1994
Papers
28
H Index
16
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37446144
Selective Killing of BRCA2-Deficient Ovarian Cancer Cells via MRE11 Blockade.
Int J Mol Sci
2023
32523988
Mre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication.
Sci Adv
2020
31872000
Data presenting the synthesis of three novel stimuli responsive hyperbranched polymers synthesised via RAFT polymerisation and the bio conjugation of folic acid.
Data Brief
2019
28733404
High-Throughput Quantitative Genetic Interaction Mapping in the Fission Yeast <i>Schizosaccharomyces pombe</i>.
Cold Spring Harb Protoc
2018
28733416
Genetic Interaction Screens in <i>Schizosaccharomyces pombe</i> Using the Pombe Epistasis Mapper (PEM) System and a Manual Colony Replicator.
Cold Spring Harb Protoc
2018
28733406
Genetic Interaction Score (S-Score) Calculation, Clustering, and Visualization of Genetic Interaction Profiles for Yeast.
Cold Spring Harb Protoc
2018
28441348
Deoxynucleoside Salvage in Fission Yeast Allows Rescue of Ribonucleotide Reductase Deficiency but Not Spd1-Mediated Inhibition of Replication.
Genes (Basel)
2017
26150418
UV induced ubiquitination of the yeast Rad4-Rad23 complex promotes survival by regulating cellular dNTP pools.
Nucleic Acids Res
2015
26201080
The DNA-Binding Domain of S. pombe Mrc1 (Claspin) Acts to Enhance Stalling at Replication Barriers.
PLoS One
2015
21660689
Detection of covalent DNA-bound Spo11 and topoisomerase complexes.
Methods Mol Biol
2011
20107609
Collaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repair.
PLoS Genet
2010
20526281
Topoisomerase I regulates open chromatin and controls gene expression in vivo.
EMBO J
2010
19264558
Screening a genome-wide S. pombe deletion library identifies novel genes and pathways involved in genome stability maintenance.
DNA Repair (Amst)
2009
19804756
A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage.
Cell
2009
19150433
Distinct requirements for the Rad32(Mre11) nuclease and Ctp1(CtIP) in the removal of covalently bound topoisomerase I and II from DNA.
Mol Cell
2009
19139281
Ctp1CtIP and Rad32Mre11 nuclease activity are required for Rec12Spo11 removal, but Rec12Spo11 removal is dispensable for other MRN-dependent meiotic functions.
Mol Cell Biol
2009
17600775
TDP1 facilitates repair of ionizing radiation-induced DNA single-strand breaks.
DNA Repair (Amst)
2007
17072889
Double-strand break repair and homologous recombination in Schizosaccharomyces pombe.
Yeast
2006
15489526
The meiotic recombination hot spot ura4A in Schizosaccharomyces pombe.
Genetics
2005
14988732
Roles of histone acetylation and chromatin remodeling factor in a meiotic recombination hotspot.
EMBO J
2004
12568722
A simple Cre-loxP method for chromosomal N-terminal tagging of essential and non-essential Schizosaccharomyces pombe genes.
Gene
2003
12032307
A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway.
Proc Natl Acad Sci U S A
2002
12019258
A 160-bp palindrome is a Rad50.Rad32-dependent mitotic recombination hotspot in Schizosaccharomyces pombe.
Genetics
2002
11726502
Fission yeast Rad50 stimulates sister chromatid recombination and links cohesion with repair.
EMBO J
2001
11226171
Novel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe.
EMBO J
2001
9858548
The msh2 gene of Schizosaccharomyces pombe is involved in mismatch repair, mating-type switching, and meiotic chromosome organization.
Mol Cell Biol
1999
9763441
The role of topoisomerase II in meiotic chromosome condensation and segregation in Schizosaccharomyces pombe.
Mol Biol Cell
1998
8032412
Immunocytochemical techniques applied to meiotic chromosomes.
Methods Mol Biol
1994
1 - 28 of 28
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row(s) 1 - 30 of 30
Collaborators
Isabelle Colson
North West Cancer Research Institute, Bangor University
Co-authored papers
2
Colm J Ryan
University College Dublin
Co-authored papers
2
Assen Roguev
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers
2
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers
2
Ulrika Axelsson
KTH - Royal Institute of Technology
Co-authored papers
1
Stephen P Jackson
Mission Therapeutics Ltd. Glenn Berge Building
Co-authored papers
1
Jacqueline Hayles
The Francis Crick Institute
Co-authored papers
1
Jiewei Xu
Quantitative Biosciences Institute (QBI), University of California san francisco
Co-authored papers
1
J??rg B??hler
University College London
Co-authored papers
1
Dong Uk Kim
Biomedical Research Institute, Pusan National University Hospital
Co-authored papers
1
Yves Pommier
Center for Cancer Research, National Cancer Institute
Co-authored papers
1
Kwang-Lae Hoe
Chungnam National University
Co-authored papers
1
Han-Oh Park
Seoul National University
Co-authored papers
1
Karl Ekwall
Karolinska Institute
Co-authored papers
1
1 - 14