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Author Details

Edgar Hartsuiker
North West Cancer Research Institute, Bangor University
1994
28
16
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37446144Selective Killing of BRCA2-Deficient Ovarian Cancer Cells via MRE11 Blockade.Int J Mol Sci2023
32523988Mre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication.Sci Adv2020
31872000Data presenting the synthesis of three novel stimuli responsive hyperbranched polymers synthesised via RAFT polymerisation and the bio conjugation of folic acid.Data Brief2019
28733404High-Throughput Quantitative Genetic Interaction Mapping in the Fission Yeast <i>Schizosaccharomyces pombe</i>.Cold Spring Harb Protoc2018
28733416Genetic Interaction Screens in <i>Schizosaccharomyces pombe</i> Using the Pombe Epistasis Mapper (PEM) System and a Manual Colony Replicator.Cold Spring Harb Protoc2018
28733406Genetic Interaction Score (S-Score) Calculation, Clustering, and Visualization of Genetic Interaction Profiles for Yeast.Cold Spring Harb Protoc2018
28441348Deoxynucleoside Salvage in Fission Yeast Allows Rescue of Ribonucleotide Reductase Deficiency but Not Spd1-Mediated Inhibition of Replication.Genes (Basel)2017
26150418UV induced ubiquitination of the yeast Rad4-Rad23 complex promotes survival by regulating cellular dNTP pools.Nucleic Acids Res2015
26201080The DNA-Binding Domain of S. pombe Mrc1 (Claspin) Acts to Enhance Stalling at Replication Barriers.PLoS One2015
21660689Detection of covalent DNA-bound Spo11 and topoisomerase complexes.Methods Mol Biol2011
20107609Collaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repair.PLoS Genet2010
20526281Topoisomerase I regulates open chromatin and controls gene expression in vivo.EMBO J2010
19264558Screening a genome-wide S. pombe deletion library identifies novel genes and pathways involved in genome stability maintenance.DNA Repair (Amst)2009
19804756A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage.Cell2009
19150433Distinct requirements for the Rad32(Mre11) nuclease and Ctp1(CtIP) in the removal of covalently bound topoisomerase I and II from DNA.Mol Cell2009
19139281Ctp1CtIP and Rad32Mre11 nuclease activity are required for Rec12Spo11 removal, but Rec12Spo11 removal is dispensable for other MRN-dependent meiotic functions.Mol Cell Biol2009
17600775TDP1 facilitates repair of ionizing radiation-induced DNA single-strand breaks.DNA Repair (Amst)2007
17072889Double-strand break repair and homologous recombination in Schizosaccharomyces pombe.Yeast2006
15489526The meiotic recombination hot spot ura4A in Schizosaccharomyces pombe.Genetics2005
14988732Roles of histone acetylation and chromatin remodeling factor in a meiotic recombination hotspot.EMBO J2004
12568722A simple Cre-loxP method for chromosomal N-terminal tagging of essential and non-essential Schizosaccharomyces pombe genes.Gene2003
12032307A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway.Proc Natl Acad Sci U S A2002
12019258A 160-bp palindrome is a Rad50.Rad32-dependent mitotic recombination hotspot in Schizosaccharomyces pombe.Genetics2002
11726502Fission yeast Rad50 stimulates sister chromatid recombination and links cohesion with repair.EMBO J2001
11226171Novel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe.EMBO J2001
9858548The msh2 gene of Schizosaccharomyces pombe is involved in mismatch repair, mating-type switching, and meiotic chromosome organization.Mol Cell Biol1999
9763441The role of topoisomerase II in meiotic chromosome condensation and segregation in Schizosaccharomyces pombe.Mol Biol Cell1998
8032412Immunocytochemical techniques applied to meiotic chromosomes.Methods Mol Biol1994
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Collaborators

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Co-authored papers 2
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Center for Cancer Research, National Cancer Institute
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Chungnam National University
Co-authored papers 1
Seoul National University
Co-authored papers 1
Karolinska Institute
Co-authored papers 1